ID   A0A1B8CQU7_9PEZI        Unreviewed;       974 AA.
AC   A0A1B8CQU7;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=FAD-binding PCMH-type domain-containing protein {ECO:0000259|PROSITE:PS51387};
GN   ORFNames=VE00_00240 {ECO:0000313|EMBL:OBT49171.1};
OS   Pseudogymnoascus sp. WSF 3629.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1622147 {ECO:0000313|EMBL:OBT49171.1, ECO:0000313|Proteomes:UP000091997};
RN   [1] {ECO:0000313|EMBL:OBT49171.1, ECO:0000313|Proteomes:UP000091997}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSF 3629 {ECO:0000313|EMBL:OBT49171.1,
RC   ECO:0000313|Proteomes:UP000091997};
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT   white-nose syndrome of bats.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000091997}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WSF 3629 {ECO:0000313|Proteomes:UP000091997};
RX   PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT   white-nose syndrome of bats.";
RL   Nat. Commun. 9:35-35(2018).
CC   -!- SIMILARITY: Belongs to the oxygen-dependent FAD-linked oxidoreductase
CC       family. {ECO:0000256|ARBA:ARBA00005466}.
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DR   EMBL; KV454566; OBT49171.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1B8CQU7; -.
DR   OrthoDB; 1641938at2759; -.
DR   Proteomes; UP000091997; Unassembled WGS sequence.
DR   GO; GO:0071949; F:FAD binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0031179; P:peptide modification; IEA:InterPro.
DR   CDD; cd04794; euk_LANCL; 1.
DR   Gene3D; 1.50.10.10; -; 1.
DR   Gene3D; 3.30.465.10; -; 2.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR012951; BBE.
DR   InterPro; IPR016166; FAD-bd_PCMH.
DR   InterPro; IPR036318; FAD-bd_PCMH-like_sf.
DR   InterPro; IPR016169; FAD-bd_PCMH_sub2.
DR   InterPro; IPR007822; LANC-like.
DR   InterPro; IPR006094; Oxid_FAD_bind_N.
DR   PANTHER; PTHR13878; GULONOLACTONE OXIDASE; 1.
DR   PANTHER; PTHR13878:SF91; L-GULONOLACTONE OXIDASE 3; 1.
DR   Pfam; PF08031; BBE; 1.
DR   Pfam; PF01565; FAD_binding_4; 1.
DR   Pfam; PF05147; LANC_like; 1.
DR   PRINTS; PR01950; LANCSUPER.
DR   SMART; SM01260; LANC_like; 1.
DR   SUPFAM; SSF56176; FAD-binding/transporter-associated domain-like; 1.
DR   SUPFAM; SSF158745; LanC-like; 1.
DR   PROSITE; PS51387; FAD_PCMH; 1.
PE   3: Inferred from homology;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000091997}.
FT   DOMAIN          522..700
FT                   /note="FAD-binding PCMH-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51387"
SQ   SEQUENCE   974 AA;  106168 MW;  46863116A26E0096 CRC64;
     MEETLCVSND IPAQTLRSSP LELLQSSLEQ ILQTLPPKES YSNEQASGFF MGYTGLAFLL
     FQISALHPGL EILGHDLIYW AKRYMEGKRS GIECFIVDKE QGCGLLNERL CFQALRACLS
     KEHSDVLAFL SDMPAVLGPY STEHGDPYET ELLYGRTGVL YLLRMLRRWV PGSASSLEEP
     IAQLAEKILV TDSDGKGNWE WNGDRRYGPP HGDIGIITQL VLTLPSLAPK LSAKVEELLS
     LQGPDGNWPS SRDTTEVKRG WERVQYCHGA PGFVCALQTL RPFYPELHDR IDQAVARGRD
     TTWSRGLLKK EPNLCHGILG NAFAFPIGSK REHFLALCTP DAIERAKELD PKVFGAAAYG
     MEVMAALQYL PSAAWTWAVC DMPIPPMLMF NDKLFRVAIR VVNLVGAGAF ALTLAPLPAV
     ADFSAFPTVL KAWCRSLPGD DSWPTVSQWK NLNSTVGGRL VKTYPLGSVC HDPAYDAAKC
     ASLQTAWTDA QLHMESSSSV MAPFFVNQSC DPWTSTSRPC TLGNYVSYSV NATSAADIIE
     AVNFAQEHNI RLVIRNTGHD YSGKSIGAGA LAVWTHHLKS TQVLDWKDSY YDGKAIKMGA
     GVQGFEAMAA AKTEGLVSIG GECPTVGVAG GYTQGGGHSA LSTSFGLGAD QTLSFEVVTA
     KGRLVTASRT ENSDLYWALS GGGGGTYGIV VSMTAKAYPD AIVGGATLIF QSSSTTADNF
     YAGVEKFHSL LPAMVDAGSM MVYFFDDTFF QIGPLTAYNK TSTDVKSILG DFVTSLDELQ
     IPYNVSYSQS ATYTEHYNTY FGPLPYGNIK VGIAQYGGRL IPRATIENNN AAFMKMARNI
     TQDGVLFIGV GTDVSAPAEI VSNSVLPAWR NTHVHATLTT PWNFTAPLAD MIALQDKMTD
     SIQPQIEAVT PGSGAYMNEA DFRQPDYKEA FFGSNYPRLL EIKDKWDGDY LFYAIKSVGG
     DHWNIAADGR MCRA
//