ID A0A1B8CVX3_9PEZI Unreviewed; 437 AA.
AC A0A1B8CVX3;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 22-FEB-2023, entry version 19.
DE RecName: Full=CBF1-interacting co-repressor CIR N-terminal domain-containing protein {ECO:0000259|SMART:SM01083};
GN ORFNames=VE04_08340 {ECO:0000313|EMBL:OBT50957.1};
OS Pseudogymnoascus sp. 24MN13.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622150 {ECO:0000313|EMBL:OBT50957.1, ECO:0000313|Proteomes:UP000092157};
RN [1] {ECO:0000313|EMBL:OBT50957.1, ECO:0000313|Proteomes:UP000092157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=24MN13 {ECO:0000313|EMBL:OBT50957.1,
RC ECO:0000313|Proteomes:UP000092157};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=24MN13 {ECO:0000313|Proteomes:UP000092157};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CWC25 family.
CC {ECO:0000256|ARBA:ARBA00006695}.
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DR EMBL; KV456996; OBT50957.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8CVX3; -.
DR STRING; 1622150.A0A1B8CVX3; -.
DR Proteomes; UP000092157; Unassembled WGS sequence.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR019339; CIR_N_dom.
DR InterPro; IPR022209; CWC25.
DR PANTHER; PTHR16196; CELL CYCLE CONTROL PROTEIN CWF25; 1.
DR PANTHER; PTHR16196:SF0; PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG; 1.
DR Pfam; PF10197; Cir_N; 1.
DR Pfam; PF12542; CWC25; 1.
DR SMART; SM01083; Cir_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000092157};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 10..46
FT /note="CBF1-interacting co-repressor CIR N-terminal"
FT /evidence="ECO:0000259|SMART:SM01083"
FT REGION 167..214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 252..274
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 337..356
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 26..58
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 188..212
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 437 AA; 50037 MW; B894854B5403E131 CRC64;
MGGDLNLKKS WHPVLMSNQK KVWEEEKKAL DERKKTELRI KELKEERAKE EIQQKLEAAG
SRKRVDRVDW MYQGPSNGQS GTTEEMEGYL LGKRRIDTLI KGNDHKKLEK QASEDSFMAL
QKANTLKDTA AKVREDPMLA IKRQEQAAYE AMMNDPIKRK QLLAVIGGEP EGKEKTKERK
HRHHHRRHHD DASDDRRHKR RRVDDSERDG RSNPVRLSVG VLEVERSVIQ GTSRLGGGVR
DQCHLEEGGI RDHLPREGDG IHDHQHHLQE EKRDETDVLR HLAEYPYLRV GDLILVNDPD
QRGTLANNLV GIPTETEIHG PMAMQRDETE IDQERATMPG NPQGPHFESV EEREAERQRK
LAAMQEDASA LDQDREKRLA ALAEKEKIVR DADEAARVKS AKYSDKADFV NGMHQKVGSM
GLADRIGRGR QGLQRDD
//
