ID A0A1B8D1A0_9PEZI Unreviewed; 1333 AA.
AC A0A1B8D1A0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
GN ORFNames=VE04_07875 {ECO:0000313|EMBL:OBT52862.1};
OS Pseudogymnoascus sp. 24MN13.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622150 {ECO:0000313|EMBL:OBT52862.1, ECO:0000313|Proteomes:UP000092157};
RN [1] {ECO:0000313|EMBL:OBT52862.1, ECO:0000313|Proteomes:UP000092157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=24MN13 {ECO:0000313|EMBL:OBT52862.1,
RC ECO:0000313|Proteomes:UP000092157};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=24MN13 {ECO:0000313|Proteomes:UP000092157};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KV456511; OBT52862.1; -; Genomic_DNA.
DR STRING; 1622150.A0A1B8D1A0; -.
DR Proteomes; UP000092157; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR Gene3D; 3.40.50.1580; Nucleoside phosphorylase domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR000845; Nucleoside_phosphorylase_d.
DR InterPro; IPR035994; Nucleoside_phosphorylase_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR46082:SF11; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR46082; ATP/GTP-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF12796; Ank_2; 2.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF01048; PNP_UDP_1; 1.
DR SMART; SM00248; ANK; 4.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53167; Purine and uridine phosphorylases; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 4.
DR PROSITE; PS50837; NACHT; 1.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000092157}.
FT DOMAIN 375..526
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT REPEAT 808..840
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 842..874
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 875..907
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 910..942
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 1333 AA; 149035 MW; 50F523497A47D43F CRC64;
MASRDDYAIG WVCALPIEVA AAKATLDRVH DNLPPGQSSN DNNNYILGSL QGHNVVVAYP
NSGVCGKTSL ADVATQLHAS YTSVRFNFMI GIAGGVPDTK EDIRLGDVVV SKSTASWPGI
VQYNVNGERT EDHFLRGRAS DQPIPMLLTA MGKAETAAIF DESKMPRYIS EIAQKDPVTF
APPGPEQDVL FEPNYDHVTI GSEESGCSHC NPDRIRSRQP REVQDPIVHY GLIASTHQLT
RHGTARDKFA HKHGILCFET EATGLKDATQ YLVIRGICDY ADSHRTELWH AYAAAAAAAY
AKEVLSFIPI VFKTIPLATN WYAEAAPVLD ALLLTRPEVD RKSLIALKGR RVDGTCEWLI
QHPHYQEWLA DANRPLLWIS GGPGKGKTML AIYITEVLQP VVDAADNVLL YYFCSNRDKN
RNTALTIMRG ILHQWIDLNP HLAKDIKNSF EGTETTKYTI SSFVTLWRVF VTLLKKSTSR
VVCVLDGLDE CEKESLRQLL DAVGNYLSKS EEKARPRLKL IIFSRPQPAV LESKLGQYQQ
IQLDASDTEI SHDVERYIFA KVAELASEQN LSEEMVAQVQ QTLRAGADGT FLWVGFVANE
LQGRSWSKID EVLRHVPKGL GGIYQRLLQQ ISDKEVLVPI LQWVVLAARP LTLEELTVAA
GIKRAGTLPA KQVTKNRLGF GGLLVKVEGD VVNLVHESAK EFFQSDQVNI KGINMFHMSQ
DTHRTLMQTC LAHVERGYGN PGGISEMSGH DPFLSYASQY WPVHFHHAIH VIDAPSEFSR
PFFQVDSPIR DEWWKVYWEQ EKNGGSPPSF TLLHLAAYFG NVPWAKLLIS KHARLNSQKD
NYGRTPPSWA VNQGHLEMVE LLLGHGARVN FKDRSMLTAL HIAVTGQHRD VVSVLLEHGA
CLEAKAEHGD TDTPLMRAIL ANSREMTQEL LEHGARVDKL PDLLGVASLK GPTDPVDERV
KELLGLQEQV FLARFKRSSR FVILVMKGLG LSLRVPFVLE LMSLYLKFMT LNRYDSLSVL
QELVQENKTD ELREWAKLYH VFFLGLVVAK NTKRLKAMGD LSTQILQKVA PRDLQALMAI
TVFTGMDTKL TAVRHRWREG DTVTAAAISD WAAIACDRDS LEFFHFGIRE FLSDFDGCVR
NGSREENILR TALLMTGHFA MIDKQEPGPI EYFSRVIAEF FQGYIGSSYE VELFSDVNQA
CANELFVISE SRDSARLRLF LTSVFQFARQ AHEEGQDRFL NVPSAACLVL CQENAIAHQW
LIGEAIPEEI GTLIAKEPPG SLQKRACKTF VECQIVGKQY GLTLPRGAPR QRVEQHLQSL
PGVGHLMNRI LSS
//
