ID A0A1B8DGL0_9PEZI Unreviewed; 615 AA.
AC A0A1B8DGL0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=VE04_01307 {ECO:0000313|EMBL:OBT58231.1};
OS Pseudogymnoascus sp. 24MN13.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622150 {ECO:0000313|EMBL:OBT58231.1, ECO:0000313|Proteomes:UP000092157};
RN [1] {ECO:0000313|EMBL:OBT58231.1, ECO:0000313|Proteomes:UP000092157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=24MN13 {ECO:0000313|EMBL:OBT58231.1,
RC ECO:0000313|Proteomes:UP000092157};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=24MN13 {ECO:0000313|Proteomes:UP000092157};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR EMBL; KV456004; OBT58231.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8DGL0; -.
DR STRING; 1622150.A0A1B8DGL0; -.
DR ESTHER; 9pezi-a0a094glz6; Fungal_carboxylesterase_lipase.
DR Proteomes; UP000092157; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR InterPro; IPR019819; Carboxylesterase_B_CS.
DR PANTHER; PTHR43142; CARBOXYLIC ESTER HYDROLASE; 1.
DR PANTHER; PTHR43142:SF3; PUTATIVE (AFU_ORTHOLOGUE AFUA_3G09070)-RELATED; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000092157};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 19..615
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5008447952"
FT DOMAIN 202..454
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 615 AA; 65046 MW; 5AE3DAF118C44E6F CRC64;
MTFLKASALL SVARLAACAA PNLPALGSDV TILSNNDLYS SHTTRTTGAL LVNTAFCQKD
AAARCTSFGE TLWDPSAEDF NLGLDRSLAY QVYQGNYGKS QLFWVASDRK GCQAIDAKGK
TKLVSCFQKL PALCTQSAPI PNATFTDTSA RFQVAQKVGK QTLTGYRDFY NWRFFGVRFA
PQPERFSYST VYDGEGSAES LESGTECVQA PGVGSEDCLF LNVWTPYLPS QKTAPATKML
KAVMFYMVGG GFVGGSASVD DLGNMASRGD VVVISINYRM ANLGFLALDD GVTNGNYGIQ
DAITALEWVK RNVKAFGGDP SRITVFGSSA GASLVRALLA SPKAKGLFAA GIMQSNPAGA
LANGPYSELQ SIQQVSSTVG AAVLNETSCS EAADKLACLR AYDPIELNNL AAVANYPVVD
GTYLTTPRLE VTGGGYAAHV PVINGGNRDE LAVLGLYLPI TDPTEAILGL GAALGFNTTA
AAAPGIFPLP PGANAAGNIF NITSRILTDV ALRGAEQAMV ASAVKHGVFP KAYAFTFNRT
YQPVGFGGDE CRAPLTTEHP AGDANAEYYK CHAGELQFVF GNILHDGLVD RDRGDVPFAQ
LVVDYWTSCA RSRAS
//
