ID A0A1B8DHX5_9PEZI Unreviewed; 670 AA.
AC A0A1B8DHX5;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Tyrosine specific protein phosphatases domain-containing protein {ECO:0000259|PROSITE:PS50056};
GN ORFNames=VE04_02160 {ECO:0000313|EMBL:OBT58542.1};
OS Pseudogymnoascus sp. 24MN13.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622150 {ECO:0000313|EMBL:OBT58542.1, ECO:0000313|Proteomes:UP000092157};
RN [1] {ECO:0000313|EMBL:OBT58542.1, ECO:0000313|Proteomes:UP000092157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=24MN13 {ECO:0000313|EMBL:OBT58542.1,
RC ECO:0000313|Proteomes:UP000092157};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=24MN13 {ECO:0000313|Proteomes:UP000092157};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
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DR EMBL; KV455991; OBT58542.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8DHX5; -.
DR STRING; 1622150.A0A1B8DHX5; -.
DR Proteomes; UP000092157; Unassembled WGS sequence.
DR GO; GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
DR GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR CDD; cd14502; RNA_5'-triphosphatase; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR000340; Dual-sp_phosphatase_cat-dom.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR InterPro; IPR016130; Tyr_Pase_AS.
DR InterPro; IPR000387; Tyr_Pase_dom.
DR PANTHER; PTHR10367:SF25; DUAL SPECIFICITY PHOSPHATASE CATALYTIC DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_1G03540); 1.
DR PANTHER; PTHR10367; MRNA-CAPPING ENZYME; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR Pfam; PF00782; DSPc; 1.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00383; TYR_PHOSPHATASE_1; 1.
DR PROSITE; PS50056; TYR_PHOSPHATASE_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000092157}.
FT DOMAIN 577..648
FT /note="Tyrosine specific protein phosphatases"
FT /evidence="ECO:0000259|PROSITE:PS50056"
FT REGION 340..369
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 385..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 670 AA; 74810 MW; F7CF8394A9F6387F CRC64;
MGILQITGLC GAAGALWYIW RLRNNKSIEV PQRRSSVAPP PPQPRELILD AEESDPGLLR
KHSEFKSFTT SRFTYPNVRV FHRKHTQAEK LPKVPAPLPL LVFIHGLGGS AAQFHPLLTS
MVNVSSCIAI DLPGCGRSSF EPRSWDAYKT DALAELLEVI IEEYREKDTK QGVVLIGHSM
GCSLAALLAS KNSPSYNGLS EHVVGFIAIC PKAEPPNEQQ TRLFKRLLWV PGTIFDLFRR
WDRRGGVNSA SVTRFVGEAA GTETRELQLR FNAQSRTPVW RRMASGSLPN YRDGIAEGGL
PGKEIWAGLD CPVFLVAGEA DHVTKAKEIA IIEGFMGTSH PVQNDTDDRS EAINDSAAPF
DSSMSRDDRA SMDATFDDEL GTFADESFED TGSMTPPTPE SPDDIEAIYD DSDAPQKELG
SLPPQPLKPK KVLKTTILPA PANHALLYMP ASVRILAGLV SDFLGSHVTQ RLSLGWQLQF
LSTSGKWDVK NLAKWQAVAP VSAPIAGIFR AMKTLREVDE NHCPEVFARD WSRWVKDVVD
ISHEAPVYDP RGLEKGGIRY HKLPTVSKIP PTSQEVTEFI NFVDRLREEQ KERKLTKGWG
DELYIAVHCH YGFNRTGFFI VCYLIEREGY EVQEALDEFA KRRPKGIRHA HFMDQLFVRY
CKGLKEAPTF
//
