ID A0A1B8DIZ1_9PEZI Unreviewed; 799 AA.
AC A0A1B8DIZ1;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=DNA mismatch repair proteins mutS family domain-containing protein {ECO:0000259|PROSITE:PS00486};
GN ORFNames=VE04_00829 {ECO:0000313|EMBL:OBT58857.1};
OS Pseudogymnoascus sp. 24MN13.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622150 {ECO:0000313|EMBL:OBT58857.1, ECO:0000313|Proteomes:UP000092157};
RN [1] {ECO:0000313|EMBL:OBT58857.1, ECO:0000313|Proteomes:UP000092157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=24MN13 {ECO:0000313|EMBL:OBT58857.1,
RC ECO:0000313|Proteomes:UP000092157};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092157}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=24MN13 {ECO:0000313|Proteomes:UP000092157};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271}.
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DR EMBL; KV455978; OBT58857.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8DIZ1; -.
DR STRING; 1622150.A0A1B8DIZ1; -.
DR Proteomes; UP000092157; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0051321; P:meiotic cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR011184; DNA_mismatch_repair_Msh2.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR PANTHER; PTHR11361:SF21; MUTS PROTEIN HOMOLOG 4; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF005813; MSH2; 1.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Meiosis {ECO:0000256|ARBA:ARBA00023254};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000092157}.
FT DOMAIN 556..572
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT REGION 746..799
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 746..765
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 799 AA; 89864 MW; C314099E4DF88B36 CRC64;
MSQICDNQFY VRTVLKLQVF EPTEILLVST SGPPNQKSKM YSLIEEEVIG SRIVCVDHDV
EAIKVATGGN FYATCCLAAS LRYMEHSLSL TFASHSLRIK YQPSEGSMMI DLSTIQSLEL
IQNITNVKSK DCLFGLLNET LTPMGSRMLR SNILQPSTQE SILKNRYEAV GELASKEEMF
FDTRNGKHVV NTLKPFLDVD KLLTNLIIQP TQPDIQHSEQ SINHILMLKT FVQCVGPVYE
ALSGARSPLL VDIRNVCRPN NITPTLKIIG EVINDDVTFQ RSPLDLRNQR TSAVKSGVNG
LLDVARQTFK EATQDVHKHV SDINDQYEMQ METRYDNARR YYLRIPESNL EGRTMPDILI
NCYRKKGYIE CQTLGLVKLN QRIEDSHQEV VLMSDKTVAQ LIDNVRAEIQ PLFRVSDSIA
MLDMLAAFAQ LVTTSDYVKP EITRCLAIKS GRHPVHEKAH SEKFIPNDVY ADKQQRFQII
TGCNMSGKST YIRSIALMTV MAQIGSFVPA QYASFPIVDQ LFARVSMDDC IEANVSTFAS
EMRETAFILR NIGKNSLVII DELGRGTSTR DGLAIALSIS EALVESQAFV WFTTHFRELG
MLVLLPLRDL KPTSPAQIMN ERAGVVNMHL KVDISQEDKM VMLYKIANGF VKEEHYGLAL
ARVVNLPPLV LEIAEKVSKT LQAQAAAKKK SSKSFAIARK RKLVLSLREV LLQAQESSMQ
GKALMEYLRK VQEEFVKRMD CIENEAEDSG DEGVVGEEEL SENDDGSDEN LGREREFNEA
DDDSDESEMT GTDKTEMLV
//
