ID A0A1B8E165_9PEZI Unreviewed; 1324 AA.
AC A0A1B8E165;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=TauD/TfdA-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=VE03_05266 {ECO:0000313|EMBL:OBT65079.1};
OS Pseudogymnoascus sp. 23342-1-I1.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1524831 {ECO:0000313|EMBL:OBT65079.1, ECO:0000313|Proteomes:UP000091879};
RN [1] {ECO:0000313|EMBL:OBT65079.1, ECO:0000313|Proteomes:UP000091879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=23342-1-I1 {ECO:0000313|EMBL:OBT65079.1,
RC ECO:0000313|Proteomes:UP000091879};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=23342-1-I1 {ECO:0000313|Proteomes:UP000091879};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964}.
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DR EMBL; KV455006; OBT65079.1; -; Genomic_DNA.
DR STRING; 1524831.A0A1B8E165; -.
DR OrthoDB; 1433837at2759; -.
DR Proteomes; UP000091879; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.60.130.10; Clavaminate synthase-like; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR InterPro; IPR042098; TauD-like_sf.
DR InterPro; IPR003819; TauD/TfdA-like.
DR PANTHER; PTHR43142; CARBOXYLIC ESTER HYDROLASE; 1.
DR PANTHER; PTHR43142:SF3; PUTATIVE (AFU_ORTHOLOGUE AFUA_3G09070)-RELATED; 1.
DR Pfam; PF00135; COesterase; 1.
DR Pfam; PF02668; TauD; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000091879};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..1324
FT /note="TauD/TfdA-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008606168"
FT DOMAIN 168..661
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT DOMAIN 1066..1317
FT /note="TauD/TfdA-like"
FT /evidence="ECO:0000259|Pfam:PF02668"
SQ SEQUENCE 1324 AA; 144245 MW; 4E44B28E7698AE1B CRC64;
MLHLALLALV LPSAIAHTLA VSNAETSLTL LYQNNLNGTD DTNHVGFLLL DPSNKRDAAK
ACEAIGESLV SRSQIKAHNS DFVSSLSYVA YAGRAQPPHL YHISDGAVAV DAHEKLIFPA
VPSRSIKLPV LCTQSSQQGQ PGDALATKGN QVTIASTGNN YIGYRNQKSF RFLGIPYADT
PQRFVHSVPY SKTRQTLNAT VYAPQCPQYG SGAESCLFLN VQTPYVPKQG SKKGLRPVLF
WIHGGGFVGG SAADAGTDGG NLASREDIVV VQIQYRLNTL GFLAIPGTDV TGNYGIADQI
NALQWVIKNI ASFGGDPDQI TIGGDSAGAG SVRVLLGSPP ANGKFQGAIA MSNLGGGVTL
GLESTYSTTY SSYLTVAESY ALAGQNVFLA AGCNQTALSE QIACLKNVPA SIVSGLSSMA
RYVVQDGTYV NTQQLDVVNR KGSTAHVPAM FGVAHDDGSS IGSTYPATPV TSELEGIQAA
LGISASYAQS VIDSGLFPLY NTGNITLDSF NVSARVATDS GFRCVDQATM LAGAQSGAFA
ASYYYEMERT IGGYDANLLG GAPETPGYPD GNPNLPYFRF HSGATAPFIF GNVSPIRDSD
DLNAAQLNSG YFAQFVKTGQ PNPSERYLET RKYGETLHAV RQTGQWKQVK DENGPIRLLD
YPSVSSGFVD VPQPDFLFNS PDTISESAST NPSIENPQIC EINARFMFNA FFGAAFTHEA
FQKTGFESFG LKSPVDPSKV FAAFKGMFDI NKPIHLLKSS EVGLDIHLFE YYLRERCGLK
VRFIKPEQLR LVPSTSWGSG ATLWCTISTD KSSSEDKEDS KEWRLISPEG EILEQVYQVG
LELHQLEMES LGQDMLKALA PLCVNDLRTI YLVHDKRMLG IVSQELESLV ERHVLTLDEA
EMLRNGIAQT ILAGSPELKE LVQCTRNGVG VKDNFVLKLI GSGKGNGIIF GEDISTEVWM
EYLVQLSEPQ VTGLNYVIQR VARQPKFDII VPSKSGKPIT ENYYLVGTFM MVDGEHLGIA
GWRSGPGRIC AVSHGGSWIC NLMRDSNVAH ASTMEYEVPR ITAHELNDTQ NVSHVNAIDD
ALQKYGIMAI TLTFPDPDST YLLKLVQSLQ RDHGHGEPLT HSSTRGWFWD VKPTPKSISA
PHHARSETMD DFPWHTDCSY ASEPPRFFGL HVLQADRCGG GTLSVVKLDK VLKFLGREAV
ETLSREEFRI EVPPEFENGT KSVIGPVLKP VRGGQEYTEE MKCRYRADII HPLTENATSA
LEALNKALAQ ARTENSDICL NLSPKMIPNG TVLLMDNGRW LHARNEVKDP ERHSRRIRWD
AREF
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