ID A0A1B8E329_9PEZI Unreviewed; 585 AA.
AC A0A1B8E329;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=VE03_03274 {ECO:0000313|EMBL:OBT65759.1};
OS Pseudogymnoascus sp. 23342-1-I1.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1524831 {ECO:0000313|EMBL:OBT65759.1, ECO:0000313|Proteomes:UP000091879};
RN [1] {ECO:0000313|EMBL:OBT65759.1, ECO:0000313|Proteomes:UP000091879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=23342-1-I1 {ECO:0000313|EMBL:OBT65759.1,
RC ECO:0000313|Proteomes:UP000091879};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=23342-1-I1 {ECO:0000313|Proteomes:UP000091879};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KV455000; OBT65759.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8E329; -.
DR STRING; 1524831.A0A1B8E329; -.
DR ESTHER; 9pezi-a0a094fhl9; Fungal_carboxylesterase_lipase.
DR OrthoDB; 3085104at2759; -.
DR Proteomes; UP000091879; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF162; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000091879};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..585
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012000563"
FT DOMAIN 65..575
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 585 AA; 63895 MW; D87751A69FBC5B09 CRC64;
MKFLLSLLAL PLVLAIPVED IPQGPAPPVL DAPVEPAPEL QARYPTPTVV IPLPQATIVG
LGGADVEQFP GIPFAQPPVG GLRLKDPQPI TKPLGTYQAT KNQAACPQFF FSDALNDDIP
TSVIGQILNS PFVQKITSQS EDCLYLNVHR PAGISADAKL PVLFWMFGGG FELGWNTMYD
GTPWVKSSIE QGKPMIFITV NYRIGGFGFL PGAEILKDGS ANLGLKDQRL GLQWVADNIA
AFGGDPEKVT IWGESAGAIS VFDHMVINEG DHTYKGKPLF RAAIMNSGSV VPADPVDCPK
GQVVYDTVVE AAGCKGTADT LACLRGLPYQ TYLNAANSVP GLLSHTSVAL SYLPRPDGTF
LTESPDVLVL NGKYARVPFI IGDQEDEGTL FALFTSYIKT PADLVKHLKT VFFHSSTDAQ
MTELVQTYNS ALLDGSPFRT GIFNNWYPEF KRLAAILGDL TFTLSRRVFL LGTSTIAPDV
PSWSYLSSYD YGTPVMGTFH GSDLIQVFFG IYPNYAAASF RAYYLSFVAT MDPNNGTDTK
YRKWPQWKDG KQLLNTYATH SQLITDDFRS KTYDFIVNNI KSLYI
//
