ID A0A1B8E6C4_9PEZI Unreviewed; 1542 AA.
AC A0A1B8E6C4;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN ORFNames=VE03_04167 {ECO:0000313|EMBL:OBT66910.1};
OS Pseudogymnoascus sp. 23342-1-I1.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1524831 {ECO:0000313|EMBL:OBT66910.1, ECO:0000313|Proteomes:UP000091879};
RN [1] {ECO:0000313|EMBL:OBT66910.1, ECO:0000313|Proteomes:UP000091879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=23342-1-I1 {ECO:0000313|EMBL:OBT66910.1,
RC ECO:0000313|Proteomes:UP000091879};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=23342-1-I1 {ECO:0000313|Proteomes:UP000091879};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
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DR EMBL; KV454991; OBT66910.1; -; Genomic_DNA.
DR STRING; 1524831.A0A1B8E6C4; -.
DR OrthoDB; 5473955at2759; -.
DR Proteomes; UP000091879; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010929; PDR_CDR_ABC.
DR PANTHER; PTHR19241; ATP-BINDING CASSETTE TRANSPORTER; 1.
DR PANTHER; PTHR19241:SF625; ATP-DEPENDENT PERMEASE PDR10-RELATED; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF06422; PDR_CDR; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000091879};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 509..531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 543..565
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 618..639
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 651..670
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 756..777
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1181..1200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1212..1235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1255..1281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1301..1324
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1336..1359
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1452..1473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 147..398
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 844..1086
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 24..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1479..1542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 29..48
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1480..1494
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1512..1526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1542 AA; 171768 MW; E48AB7934BF43FE1 CRC64;
MATQPVPGAF GVLPEAQAVA ANAIGHKAES ERPVTEDTLH DETDTSYSEN NDKQVTDLAR
TFTQASIRNE QGELDNPFTS TDPALHPHSE KFNARAWTKN LVGITSRDPE RYPTRTAGVA
YKNLNVHGFG NPTDYQKTFG NYPLEAMGWI NKLRGKGQHK IQILRDFEGL VRSGEMLVVL
GRPGSGCSTL LKTISGETNG FFIDRESTIN YQGIAAQQMH NDFRGECIYQ AEVDVHFPQL
TVGQTLKFAA LARAPNNRIP GVSREQYAEH MRDVVMAMFG LSHTINTNVG NDFIRGVSGG
ERKRVSIAEC CVGQSPLQCW DNSTRGLDSA TALEFVKTLR LSTNISGATA IVAIYQASQS
IYDVFDKVAV LYEGRQIYFG HKYKAKEFFV NLGFDCPERQ TTADFLTSLT SPLERIVRPG
FEHSTPKTPD EFAAAWHKSA DRAELLREIE EFETQYPIGG AHLEKFKEGR RAQQARGQRI
KSPYTISVPM QVKLCVTRGF QRLRGDMSLL FAGIFGNTVM ALVIASVFFN LQDNTQTLFS
KGALLFFAIL INAFSSALEI LTLFAQRPIV EKHTKYAFYH PFAEAIASMI CDMPNKIGSS
IFFNITLYFM TNLKRTPGAF FTFILFGFSC VMAMSMFFRS IGSMARSLPE ALGPAAVIIL
ALIIYTGFTI PTVDMHPWFR WINYIDPVAY AFESLMVNEF SGRQIPCTQF VPRGGDYDKL
SLANKVCVTT GAEAGSAVLD GDTWLRVNYG YERSHLWRNL GILWALVVFG CAVHLLATEW
ISAKKSKGEV LLFPRGKVPE LASAADDEEG TQDDRINTNT LQAVTTTAAA GEAPPSIQRQ
TAIFHWQGVN YDIKIKKEPR RLLDDVDGWV KPGTLTALMG VSGAGKTTLL DVLASRVTMG
VVTGQMLVDG RQRDSGFQRK TGYVQQQDLH LATSTVREAL TFSALLRQPK ATPHHEKVAY
VDEVIKVLEM ESYAEAVVGV PGEGLNVEQR KRLTIGVELA AKPALLLFLD EPTSGLDSQT
AWSIIALLRK LANNGQAILC TIHQPSAILF QEFDRLLFLA KGGRTVYFGD VGENSSILTD
YFVRNGARPC RIDENPAEWM LEVIGAAPGS TTTVDWPVAW NESDEKAEVR SQLADMRRQL
IEKEVETDST SLDEYAAPIG LQLATVTQRV FQQFWRTPSY LYSKTFLCSS TGLFIGFSFW
DAPTSMAGIQ NQLFSIFMLL TIFGNLVQQM MPHFVTQRSL YEVRERPSKT YSWKIFIMSN
IIVELPWNSL MSVILFATYY YPIGMHRNAR IAGEFHERGG LMFLYVWSFL MFTSTFSTMI
IAGMETAEAG GNIANLLFSL CLIFCGVLAG PTVMPRFWIF MYHLSPFRYL VDGMLSVGIA
NVNVTCQPRE ILHLDPTLGK TCAQFMGEFI GTFGGYLVND DATTNCEYCS VGKSNDLLKA
FSSEYSHRWR NFGILQGYVL FNAAMAVFIY WLARVPKNSG KEEPPTEEEL ALQKSRTRNS
TTAAGGLEKT ATRDSARGKR RTWGSRGENK LSPADEIVVE KQ
//
