ID A0A1B8E6Y5_9PEZI Unreviewed; 505 AA.
AC A0A1B8E6Y5;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=VE03_04435 {ECO:0000313|EMBL:OBT67123.1};
OS Pseudogymnoascus sp. 23342-1-I1.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1524831 {ECO:0000313|EMBL:OBT67123.1, ECO:0000313|Proteomes:UP000091879};
RN [1] {ECO:0000313|EMBL:OBT67123.1, ECO:0000313|Proteomes:UP000091879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=23342-1-I1 {ECO:0000313|EMBL:OBT67123.1,
RC ECO:0000313|Proteomes:UP000091879};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091879}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=23342-1-I1 {ECO:0000313|Proteomes:UP000091879};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR EMBL; KV454990; OBT67123.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8E6Y5; -.
DR STRING; 1524831.A0A1B8E6Y5; -.
DR OrthoDB; 1743223at2759; -.
DR Proteomes; UP000091879; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF423; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000091879};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..20
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 21..505
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5008447998"
FT DOMAIN 26..356
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 505 AA; 54759 MW; 37E9556E1AE8DF7E CRC64;
MKLSDVLFGA ILCISTPVNG KWTAGQEVDT QSGPVFGSAA SKATNVSIYL GIPYAQPPIG
DLRFAAPLPY SGNTVSPVRY QTFSLGSQIP KKKNLSAAGL ATVAQLTRGN NDTSEDCLTI
NVWTKPQTGE KKKAVVIWVN GKGYTTGASS DPVYDGQFIV NEHDIILVTF NYRMNIFGFP
GNYHGTTNIG LLDERLAVEW VRDNIAGFGG DPARITLIGD SAGAGLVDLY SFAFVNDPII
SGMGLLSGTP SLRGWESDSW DKATRDWNSV TCDICRMGTE TDPAEVLACM RNKTTAEITA
AIPINSSPYG TKAFFPNTDG KVVFSEYYEL TRVGNFTKVP LLIGSTDDEM AYHRTMATVF
APSYGYGNTD YEWEDLSYYT CPASDRAERT AALDVPTWRY GYFGDFKDAR LTTAAHGRIH
HGSDVLLIFG TALVPGVTQD ADEIKLAKYA RGALAAFAKN PKTGLKTYGW PLYNPKTRSL
VQLGKDNKVG TFAVTPAAFD KGCDY
//
