ID A0A1B8ELS4_9PEZI Unreviewed; 1205 AA.
AC A0A1B8ELS4;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 08-NOV-2023, entry version 35.
DE RecName: Full=Zn(2)-C6 fungal-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=VF21_08192 {ECO:0000313|EMBL:OBT72248.1};
OS Pseudogymnoascus sp. 05NY08.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622149 {ECO:0000313|EMBL:OBT72248.1, ECO:0000313|Proteomes:UP000092096};
RN [1] {ECO:0000313|EMBL:OBT72248.1, ECO:0000313|Proteomes:UP000092096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05NY08 {ECO:0000313|EMBL:OBT72248.1,
RC ECO:0000313|Proteomes:UP000092096};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05NY08 {ECO:0000313|Proteomes:UP000092096};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
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DR EMBL; KV458892; OBT72248.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8ELS4; -.
DR STRING; 1622149.A0A1B8ELS4; -.
DR OrthoDB; 2785358at2759; -.
DR Proteomes; UP000092096; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR GO; GO:0030544; F:Hsp70 protein binding; IEA:InterPro.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR CDD; cd06257; DnaJ; 1.
DR CDD; cd10747; DnaJ_C; 1.
DR CDD; cd10719; DnaJ_zf; 1.
DR CDD; cd12148; fungal_TF_MHR; 1.
DR CDD; cd00067; GAL4; 1.
DR Gene3D; 1.10.287.110; DnaJ domain; 1.
DR Gene3D; 2.10.230.10; Heat shock protein DnaJ, cysteine-rich domain; 1.
DR Gene3D; 2.60.260.20; Urease metallochaperone UreE, N-terminal domain; 2.
DR Gene3D; 4.10.240.10; Zn(2)-C6 fungal-type DNA-binding domain; 1.
DR InterPro; IPR002939; DnaJ_C.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR018253; DnaJ_domain_CS.
DR InterPro; IPR044713; DNJA1/2-like.
DR InterPro; IPR008971; HSP40/DnaJ_pept-bd.
DR InterPro; IPR001305; HSP_DnaJ_Cys-rich_dom.
DR InterPro; IPR036410; HSP_DnaJ_Cys-rich_dom_sf.
DR InterPro; IPR036869; J_dom_sf.
DR InterPro; IPR007219; Transcription_factor_dom_fun.
DR InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR InterPro; IPR001138; Zn2Cys6_DnaBD.
DR PANTHER; PTHR43888:SF10; DNAJ-LIKE-2, ISOFORM A; 1.
DR PANTHER; PTHR43888; DNAJ-LIKE-2, ISOFORM A-RELATED; 1.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF01556; DnaJ_C; 1.
DR Pfam; PF00684; DnaJ_CXXCXGXG; 1.
DR Pfam; PF04082; Fungal_trans; 1.
DR Pfam; PF00172; Zn_clus; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SMART; SM00906; Fungal_trans; 1.
DR SMART; SM00066; GAL4; 1.
DR SUPFAM; SSF46565; Chaperone J-domain; 1.
DR SUPFAM; SSF57938; DnaJ/Hsp40 cysteine-rich domain; 1.
DR SUPFAM; SSF49493; HSP40/DnaJ peptide-binding domain; 2.
DR SUPFAM; SSF57701; Zn2/Cys6 DNA-binding domain; 1.
DR PROSITE; PS00636; DNAJ_1; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
DR PROSITE; PS51188; ZF_CR; 1.
DR PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|PROSITE-
KW ProRule:PRU00546}; Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000092096};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833, ECO:0000256|PROSITE-ProRule:PRU00546};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00546}.
FT DOMAIN 64..93
FT /note="Zn(2)-C6 fungal-type"
FT /evidence="ECO:0000259|PROSITE:PS50048"
FT DOMAIN 793..858
FT /note="J"
FT /evidence="ECO:0000259|PROSITE:PS50076"
FT DOMAIN 924..1007
FT /note="CR-type"
FT /evidence="ECO:0000259|PROSITE:PS51188"
FT ZN_FING 924..1007
FT /note="CR-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00546"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 121..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1175..1205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 26..43
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..159
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1182..1196
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1205 AA; 133397 MW; FDA62251F392D9C2 CRC64;
MDPYPPWQNG PLDNRLTGPS PADETARLQA PSSSSNSTGG PSLSPVAAAL PEARVRRRNR
MITSCLECRR RKLKCDKSHP CVNCTKGHRD CIFLAPALDQ ASRLKLTEIK DQVGSLESLL
GKGAQQPASD ATLPHIEGNP ADIKGEDLPQ AEDEKDLEPT PLAVVDAVYE DDADDDLLDL
GIQIGRMRIT ERIGGFFRPR LAQELAYSLY DTSKPSLSPD NINTTPSGVQ TYQYLMPSPA
YIAPASGFVF GHAGNGSSLI DYLPTRLAAD RLVKQYFTVV HPVAQLLHYP SFEKEYENFW
EDISLGIEPP TSLQAIVFAA MFSGAVSMSE MVILRDFGVP KDRLIDNFKS GTETALSKSH
FLRTTKVETL QAFVIYLIPL CRAETSRAHS VLVGAAIRMA ECMGLHRDGE TYGLNPIETQ
VRRLIWYQLC FLDIRTCEAQ GPRPSIRRGD FDTRLPINVN DVDLHANGKP VTVVDRWVDA
TFTTMRFEVN EMMRLIWSER PRIESRKSTL TNLLGKIEAF RRHLAEKYDH LIDERVPFQR
FAKMVKNLLL GRLTVMVLHP YHNSVQNMMP PRLRKMLIAA ATNTVENAMW IDNVPDVQPW
AWYGGAFNQY HSAFLLLLDS HFFSHDENLD RIWHCLDYVF ETDPSETREV KARKVLCELQ
EKTTVYQQFR KMRASPAMLK HVGQRPPRRV DRNINSGASS VSAHHGGVVG TEPSLIGKVP
VPDAVFAGVS NGEALWALPN YGSPAGSSDS GGVPCQANPV RMENTKMEYS MPEIDWDAFD
ILFPPNESGE MMQQGYATGV SPTCTEAELK KAYKVGALKH HPDKNAHNPD AADKFKDLSH
AYEILSDPQK RQIYDQYGEE GLEGGGGGGG MNAEDLFSQF FGGGGGVFGG GGGMFGGGMG
QRGPPKARTI HHVHKVSLED IYRGKVSKLA LQKSVICSKC DGRGGKEGAV KKCTGCDGHG
MKTMMRQMGP MIQRFQTVCP DCNGEGEIIR EKDKCKQCNG KKTVVERKVL HVHVDRGVQS
GHKIEFRGEG DQTPGVQPGD VVFEIEQKPH ARFQRKGDDI FYSAEIDLVT ALAGGNIFVE
HLDERWLSVD ILPGEVINPG SVKMVRGQGM PSHRHHDFGN LYIQFDVKFP EKNWTANPAE
FDALKSILPP TVQPILPPAE TMTEAVDLED VDASQQARAA GHGMMDDDDE DGHPAGGERV
QCASQ
//
