ID A0A1B8EN35_9PEZI Unreviewed; 1087 AA.
AC A0A1B8EN35;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 22-FEB-2023, entry version 21.
DE RecName: Full=FAD-binding FR-type domain-containing protein {ECO:0000259|PROSITE:PS51384};
GN ORFNames=VF21_08137 {ECO:0000313|EMBL:OBT72597.1};
OS Pseudogymnoascus sp. 05NY08.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622149 {ECO:0000313|EMBL:OBT72597.1, ECO:0000313|Proteomes:UP000092096};
RN [1] {ECO:0000313|EMBL:OBT72597.1, ECO:0000313|Proteomes:UP000092096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05NY08 {ECO:0000313|EMBL:OBT72597.1,
RC ECO:0000313|Proteomes:UP000092096};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05NY08 {ECO:0000313|Proteomes:UP000092096};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
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DR EMBL; KV458883; OBT72597.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8EN35; -.
DR STRING; 1622149.A0A1B8EN35; -.
DR OrthoDB; 5488444at2759; -.
DR Proteomes; UP000092096; Unassembled WGS sequence.
DR GO; GO:0016903; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors; IEA:InterPro.
DR CDD; cd06207; CyPoR_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR Gene3D; 3.40.50.80; Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module; 1.
DR Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR Gene3D; 2.40.30.10; Translation factors; 1.
DR InterPro; IPR003097; CysJ-like_FAD-binding.
DR InterPro; IPR017927; FAD-bd_FR_type.
DR InterPro; IPR001709; Flavoprot_Pyr_Nucl_cyt_Rdtase.
DR InterPro; IPR039261; FNR_nucleotide-bd.
DR InterPro; IPR023173; NADPH_Cyt_P450_Rdtase_alpha.
DR InterPro; IPR001433; OxRdtase_FAD/NAD-bd.
DR InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR InterPro; IPR017938; Riboflavin_synthase-like_b-brl.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR PANTHER; PTHR19384; NITRIC OXIDE SYNTHASE-RELATED; 1.
DR PANTHER; PTHR19384:SF109; SULFITE REDUCTASE [NADPH] FLAVOPROTEIN COMPONENT; 1.
DR Pfam; PF00667; FAD_binding_1; 1.
DR Pfam; PF00175; NAD_binding_1; 1.
DR Pfam; PF01558; POR; 1.
DR PRINTS; PR00371; FPNCR.
DR SUPFAM; SSF52343; Ferredoxin reductase-like, C-terminal NADP-linked domain; 1.
DR SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR SUPFAM; SSF63380; Riboflavin synthase domain-like; 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
DR PROSITE; PS51384; FAD_FR; 1.
PE 4: Predicted;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000092096}.
FT DOMAIN 700..937
FT /note="FAD-binding FR-type"
FT /evidence="ECO:0000259|PROSITE:PS51384"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1087 AA; 118871 MW; D0C9A2A753B0C63C CRC64;
MHLQQHQEPF GGPAGDSKWN KEKESPSAAK QFTQKSSALP FGQPINFASV SGPTYVTAQT
LVQQVAYSLS DKLYSYSPET FDLDISAKDW AAAKAKNAHG YPTSISAMQT RAGAGSIALG
YMFSKDFDLS KRHIPQSLLA SAGTLNHLRP ALDQLSLLYS VANPFVAHIT AVDYASGSSS
GLVTDYTSAL AVAEDLGLGL VSSASPYEAQ HISLFATLLA TVLPTIHIYD GIKVGRDTVR
VIDVLDQAGL KGVYTAVSKE IAAISKKADV DSKVQQVLKA FNDELGTAYD LFEYQGHETP
DTVLVVFGTV EAALTSQVAT KLSESGSKVG VINVRVYRPF VEEAFIAALP ASVKTVAVLG
QVQDASEVAD KSVRSALFGD VTAALAFSDK FSPALSIVDS KYAREQSFTP DSIATLFSQL
DTKAVSDAEE VSIQLLAPGK AEQYTFWDLD ESVARSAPAA ISKFLSNDSK TNVFLKQAYD
NFVQGGVVRS DIRNSKKSID TSYPIEEADI AVVGDEKIFK DLDVLASLKS GGKLIVKLPG
LKDEDLEKKL PASVRRELQA KNIQLYVVDP AASAAVGKDA ALETQLLEIA FLRIARPDVL
TNGLDKLVAI SGNAATLAEI TTDLDKALRQ FEVPAAWAEV EIDTKERELP ADVQTSSFTT
FDKAEVEEPA LLKDWQSAAK GLVFKEAYGT VAALRPDLSV KTFTVKVQEN RRLTPQTYDR
NIFHIEFDLG TSGLKYNIGE ALGIHAKNDE QEVQMFMVAY GLNADDVVEV PSREDVSVLE
TRTVYQSLMQ NIDIFGKPPK KFYEALAEFA TDENEKKELL TLAGPEGANE FKRRAEVDTI
TYADILLEFP SAHPSFHDIA QIVSPMKRRE YSIASSQMVN PTTVALMIVV VNWVDPKGRD
RFGQATRYLS QLPVGTDVTV SVKPSVMKLP TKDSAPLIMA GLGTGLAPFR AFVQYRAMQK
AQGIEIGSIL LYMGSRHQRE EYLYGEEWEA YQDAGVITLL GRAFSRDQPE KIYIQDRMRQ
TVDDIITAYI EEEGSFYLCG PTWPVPDVTE VLEEAISKNA KALGKKVDSR KAIDQLKEEQ
RYVLEVY
//
