ID   A0A1B8EQ96_9PEZI        Unreviewed;       298 AA.
AC   A0A1B8EQ96;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   22-FEB-2023, entry version 17.
DE   RecName: Full=NAD-dependent epimerase/dehydratase domain-containing protein {ECO:0000259|Pfam:PF01370};
GN   ORFNames=VF21_07197 {ECO:0000313|EMBL:OBT73546.1};
OS   Pseudogymnoascus sp. 05NY08.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1622149 {ECO:0000313|EMBL:OBT73546.1, ECO:0000313|Proteomes:UP000092096};
RN   [1] {ECO:0000313|EMBL:OBT73546.1, ECO:0000313|Proteomes:UP000092096}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05NY08 {ECO:0000313|EMBL:OBT73546.1,
RC   ECO:0000313|Proteomes:UP000092096};
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT   white-nose syndrome of bats.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000092096}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=05NY08 {ECO:0000313|Proteomes:UP000092096};
RX   PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT   white-nose syndrome of bats.";
RL   Nat. Commun. 9:35-35(2018).
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DR   EMBL; KV458861; OBT73546.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1B8EQ96; -.
DR   STRING; 1622149.A0A1B8EQ96; -.
DR   OrthoDB; 5486426at2759; -.
DR   Proteomes; UP000092096; Unassembled WGS sequence.
DR   CDD; cd05254; dTDP_HR_like_SDR_e; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR005913; dTDP_dehydrorham_reduct.
DR   InterPro; IPR001509; Epimerase_deHydtase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR10491; DTDP-4-DEHYDRORHAMNOSE REDUCTASE; 1.
DR   PANTHER; PTHR10491:SF4; METHIONINE ADENOSYLTRANSFERASE 2 SUBUNIT BETA; 1.
DR   Pfam; PF01370; Epimerase; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000092096}.
FT   DOMAIN          13..154
FT                   /note="NAD-dependent epimerase/dehydratase"
FT                   /evidence="ECO:0000259|Pfam:PF01370"
SQ   SEQUENCE   298 AA;  33582 MW;  AA03B705D161DD68 CRC64;
     MATTTATEKP SYLIWGGAGW VAGHLKTLLE SQGKTVTTTT VRMQNREAVI AELQRVKPTH
     VLNCAGCTGR PNVDWCEDNK EDTIRSNVIG TLNLADCCFL EKVHLTVFAT GCIYTYDEKH
     PIGGPGYLET DKANFDGSFY SETKAHVEEV MKTYPNVLIL RLRMPVSDDL HSRNFVTKIS
     KYERVVDIPN SNTLLHDLLP ASILLAEHQE TGIYNFTNPG AISHNEVLTL FKQYVRPDFT
     WKNFSLEEQS KVIKAGRSNC KLDTTKLITK LKEYDFEVPE VHEAYAQCFQ RMAKAGVQ
//