ID A0A1B8EUQ6_9PEZI Unreviewed; 1014 AA.
AC A0A1B8EUQ6;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=RING-type domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=VF21_06531 {ECO:0000313|EMBL:OBT75089.1};
OS Pseudogymnoascus sp. 05NY08.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622149 {ECO:0000313|EMBL:OBT75089.1, ECO:0000313|Proteomes:UP000092096};
RN [1] {ECO:0000313|EMBL:OBT75089.1, ECO:0000313|Proteomes:UP000092096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05NY08 {ECO:0000313|EMBL:OBT75089.1,
RC ECO:0000313|Proteomes:UP000092096};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05NY08 {ECO:0000313|Proteomes:UP000092096};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- SIMILARITY: Belongs to the SH3RF family.
CC {ECO:0000256|ARBA:ARBA00008649}.
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DR EMBL; KV458834; OBT75089.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8EUQ6; -.
DR STRING; 1622149.A0A1B8EUQ6; -.
DR OrthoDB; 1462937at2759; -.
DR Proteomes; UP000092096; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.60.90; -; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR InterPro; IPR043145; Znf_ZZ_sf.
DR PANTHER; PTHR16079:SF4; E3 UBIQUITIN-PROTEIN LIGASE CHFR; 1.
DR PANTHER; PTHR16079; UBIQUITIN LIGASE PROTEIN CHFR; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF57850; RING/U-box; 2.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50002; SH3; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000092096};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}; Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 23..78
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 950..1012
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 104..130
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 158..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 339..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 532..578
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..182
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 198..230
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..277
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 339..369
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..418
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 435..490
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..578
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1014 AA; 112418 MW; 71D5B2EA47008E9B CRC64;
MEAANQGLDL ERELTCSVRK PQPICTEVLY QPLTLLDCLH TFCGACLKEW FAFQLNSARA
SGASSSSGSN PVTCPSCRAV VRATKNNATV TTLLEMFLAA NPDKGRTAEE KDDVKNKYSP
GDDVMPKPEE REKTLRERMA EDDDGRLIQQ VQMASLREVG VELPEERRER RRRREERARA
SGRTSSRTAS REASSDPAGS GPDRERRRAE EDSGSESRRR REERREERAS ASASSPTTLH
PESTRALERR RRRSEEAARR TQDESRTRND DANRTAVRQI EHQSSLRSLI SSSDVDSREM
EEEILRQIRE EGLLDGIDLE NIDVNQEDQI SERIAEAFRR RQRERAEQVV APEPRNRSPS
DRSEHRSATS SRTRQTMTTA PPMATARRLP HSRSLSAASQ ADEATRASPR TSATRLEPQS
SDEGRRRRRT ASGGHRSTRS ATSPAPSSSP ITRPAARSAT DLTERSTSSQ IVPTRPLMSV
DTRSTTEPVP TSLTTVADVV ELATGRRRLP TLSPRSQVAG EAEIAASPLE LQSSHTRTAS
QAPAYPPPPV PAATTPQDSQ PGLIPAGTLS HHSTATERAS ALQAVSRPTS SESTASQRVS
LPRFPEPSIQ CNRCHKSHIE YELHYSCSIC ARGEWNLCLG CYRSGCGCEH WFGFGYAAWA
KWDKARAAGH IPPNAEKPHM LFAERYVPPR ITPGGAEGRR TLTTEDPARR LQSGAFCASC
QEWANECYWR CDSCNEGDWG FCNNCVNQGR CCTHPLLPLL YKPDNRDAEP MSPTHDHQTP
RTATLLTGPG VVELGSFKPL SFRVECDACH YPIQPTQTRF HCFQCTSALP GREAGDYDLC
TTCYHSMVNK KRISNENGHL GWRRCLQGHR MIIVGFEDAR GGQRRVIVQD RVGGRGLFEE
PAKTQDAVDA GLQQWSWAEG ARARLVTNNV SSTAPTGNPA MTREFPPDGG VGMRAVALWS
WYPKEGEGAN ELLFPRGAEV REVVDVNGDW FHGSFMGAKG LFPAPYVRVL DSAS
//
