ID A0A1B8F2F5_9PEZI Unreviewed; 779 AA.
AC A0A1B8F2F5;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=SAM and PH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=VF21_03198 {ECO:0000313|EMBL:OBT77799.1};
OS Pseudogymnoascus sp. 05NY08.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622149 {ECO:0000313|EMBL:OBT77799.1, ECO:0000313|Proteomes:UP000092096};
RN [1] {ECO:0000313|EMBL:OBT77799.1, ECO:0000313|Proteomes:UP000092096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05NY08 {ECO:0000313|EMBL:OBT77799.1,
RC ECO:0000313|Proteomes:UP000092096};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05NY08 {ECO:0000313|Proteomes:UP000092096};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KV458800; OBT77799.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8F2F5; -.
DR STRING; 1622149.A0A1B8F2F5; -.
DR OrthoDB; 1405875at2759; -.
DR Proteomes; UP000092096; Unassembled WGS sequence.
DR CDD; cd09535; SAM_BOI-like_fungal; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR PANTHER; PTHR12844; CONNECTOR ENCHANCER OF KINASE SUPPRESSOR OF RAS; 1.
DR PANTHER; PTHR12844:SF42; CONNECTOR ENHANCER OF KSR PROTEIN CNK; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF07647; SAM_2; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50105; SAM_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000092096}.
FT DOMAIN 201..265
FT /note="SAM"
FT /evidence="ECO:0000259|PROSITE:PS50105"
FT DOMAIN 620..762
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..34
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 266..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..597
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 779 AA; 86741 MW; 280754F9875F3D81 CRC64;
MATRQQASSS RRASQLSQQR TAVLPPLDTR GEMFQKGQHG SFFDMKALAP RPMSSSTEMY
DTDFEDDGSE IEEGEYSPRI SINSAGRRSQ TTLSSFEELP TPKSNSLHGF DFQLQQAQAP
RKSVEGPKGP HLFRISQEVA PEEEYYLTMS PVTPRYAPSS RPDTAFRVPS MPYPQPELKH
RPISTLTAAV TKLNKMEVAM WTPRQVARWM YHAGFEPAIV EKFEENDISG EILTTLKFED
LRELDIQSFG QRHKLWAEIH TLRGDAVGAP TSPTEIDCGS SDDDERTHKK SKPRRKHKKS
SFEDIISPLE SVSIVGIEQL MPKPHKCSKG DNCSRWKKQQ RLIQQFKMGH PVSPDGGMIL
IAGDPGNPFT AEAVRPFSEA QPSVVASSDL LGPGEIPSFS HLDPAQLAAL ASRDPQDNVK
QFLNFQHVEQ NWSSEEPATP PYEMFPSLPA SLQHTAQPTH PLPNLRNLPK LAIPPPRPPR
SASAMAFSPG PMDRAEALSP DLRSARQPYR FGTPASDMDV PVTAINLGPI SRDASQSVPP
NMSYRNNVPA AGPPLSRSAS RSSRRPSYQA GLPRLDEDPV VAPPRPHRSS VLGPISPPRP
VVASNAYSPV RAPAERSTDD LGHQGWMRKR KTRMLRHEWH EHHFTLRGTR LAMHKDERAR
EVLESIDVDD YAVACSSLAS SKINTAFKAM NIKLGKKEEE GAFAFQLIPA AVEKAEKLKK
NRESGIFGSS SVEKDKVKTH HFAVKSRDER IDWMRELMLA KALKQKGEGF EINVNGNMI
//
