ID A0A1B8F2Y4_9PEZI Unreviewed; 770 AA.
AC A0A1B8F2Y4;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=polynucleotide adenylyltransferase {ECO:0000256|ARBA:ARBA00012388};
DE EC=2.7.7.19 {ECO:0000256|ARBA:ARBA00012388};
GN ORFNames=VF21_04298 {ECO:0000313|EMBL:OBT77948.1};
OS Pseudogymnoascus sp. 05NY08.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1622149 {ECO:0000313|EMBL:OBT77948.1, ECO:0000313|Proteomes:UP000092096};
RN [1] {ECO:0000313|EMBL:OBT77948.1, ECO:0000313|Proteomes:UP000092096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05NY08 {ECO:0000313|EMBL:OBT77948.1,
RC ECO:0000313|Proteomes:UP000092096};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092096}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=05NY08 {ECO:0000313|Proteomes:UP000092096};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- SIMILARITY: Belongs to the DNA polymerase type-B-like family.
CC {ECO:0000256|ARBA:ARBA00008593}.
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DR EMBL; KV458799; OBT77948.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8F2Y4; -.
DR STRING; 1622149.A0A1B8F2Y4; -.
DR OrthoDB; 21395at2759; -.
DR Proteomes; UP000092096; Unassembled WGS sequence.
DR GO; GO:1990817; F:poly(A) RNA polymerase activity; IEA:UniProtKB-EC.
DR GO; GO:0016070; P:RNA metabolic process; IEA:UniProt.
DR CDD; cd05402; NT_PAP_TUTase; 1.
DR Gene3D; 1.10.1410.10; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002058; PAP_assoc.
DR InterPro; IPR002934; Polymerase_NTP_transf_dom.
DR InterPro; IPR045862; Trf4-like.
DR PANTHER; PTHR23092:SF15; INACTIVE NON-CANONICAL POLY(A) RNA POLYMERASE PROTEIN TRF4-2-RELATED; 1.
DR PANTHER; PTHR23092; POLY(A) RNA POLYMERASE; 1.
DR Pfam; PF01909; NTP_transf_2; 1.
DR Pfam; PF03828; PAP_assoc; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81631; PAP/OAS1 substrate-binding domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000092096}.
FT DOMAIN 446..548
FT /note="Polymerase nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF01909"
FT DOMAIN 620..697
FT /note="PAP-associated"
FT /evidence="ECO:0000259|Pfam:PF03828"
FT REGION 1..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 278..388
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..68
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 98..138
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..213
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..229
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..310
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 343..357
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 358..373
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 770 AA; 85881 MW; AF74CA9CDCDEA436 CRC64;
MSRPAGLPPR PVTAAYDLRS GNSYRPLPPP PKLSYDNQNR GDSSHRNDDT YRPRDSGHHR
HDENRAPGTS AYRGDPPSFP RGGADSYRPP SSDFSFRRDA PETIDVARTH DSYRPSGATR
HGQDRGPRHR DSRQDSSRQG ARGRGGYRGR GGFSKKAAER PFLQTNRAPT PELMPGMDET
VGTAPKYLAV EDMSDSEEAD MDVSDDEDYK PEDDEEEQPK KKQVRTEVKA SADGDSVPRW
SNPDPYTALP PPDESSVKKK DVVKLIRKAR VSAGLNDAAK TTAETDDFIS FDFGDDNLGG
DEDESDDESV VEVPGAPTGP RNGNYSHREE VLGPRDAAKA QEVTTPTGKS RPIDTSTDPD
LGNRKRTYDD KIKGPSLVPK PTPKGPATGN IVKEWKAKAG IDDTPWLANH YPSSKMGSWL
HMEIMDFFHR FKPAEVEENM RGALISDLRR AVQKVWHDAD ILPFGSYPAG LYLPTADMDL
VFVSRGYMDG GYGKYTNKNA LFRFRDFLDR EKIAAPYSIE VISKAKVPLV KYIDYYTGLR
VDVSFENDTG LIANKTFQNW KDTFPAMPIL VTIVKQFLAM RGLNEPVNGG IGGFTVTCLV
VSLLQHMPQI QSGNMIPEHH LGEILMEFFD LYGNEFNVTS TAIQLKPPAY VSKASTHHSN
PLLLHKSNAP QNNARQIVYR AGNLDRFSII DPNNSSNDIS GGSHNTQAIR KAFSRAFDDL
FKHMSDLSTK SIEERRGQSV LGVILGGNYS SFEVQRNHLE RIWQKEHDRR
//
