ID   A0A1B8FE44_9PEZI        Unreviewed;       593 AA.
AC   A0A1B8FE44;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   RecName: Full=Uric acid-xanthine permease {ECO:0008006|Google:ProtNLM};
GN   ORFNames=VE02_10101 {ECO:0000313|EMBL:OBT81804.1};
OS   Pseudogymnoascus sp. 03VT05.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1622148 {ECO:0000313|EMBL:OBT81804.1};
RN   [1] {ECO:0000313|EMBL:OBT81804.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=03VT05 {ECO:0000313|EMBL:OBT81804.1};
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT   white-nose syndrome of bats.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC       2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR   EMBL; KV459640; OBT81804.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1B8FE44; -.
DR   Proteomes; UP000091872; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   InterPro; IPR006042; Xan_ur_permease.
DR   NCBIfam; TIGR00801; ncs2; 1.
DR   PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR   Pfam; PF00860; Xan_ur_permease; 2.
DR   PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        76..95
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        115..131
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        191..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        219..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        283..301
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        310..328
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        340..366
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        435..457
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        463..483
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        495..514
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        526..552
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..22
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   593 AA;  62851 MW;  553A1936C18FCABD CRC64;
     MDEYLGPDTI TSQNASPSSF GQRVKGRLRN LGRAFTTRDG LIGDYDYGFL LRPNLPFMKK
     SPYQAPFFGL NDKMPVALGM LLGLQHALAM LAGVITPPLI LSGTGGANLS GPEQQYLVST
     ALIISGIMSI VQINRFRIPK TNYFVGTGVL SVVGVSFAII PIAQGAFKQM YANGYCPTSD
     NGAPLPCPRG YGALIGTSSV CALTTVLISF IPPKMLQRLF PSIVTGPTVM LIGVKLIETG
     FKNWMGGSGP CFDPASNGKQ ADLFALCPDI NAPHALPWGS PEYLGLGFSV FITILFCERF
     GSPIMKSTSV VWGLLVGCII AAATGYFPKG GIDSAPAVSF VWLYTFPLSI YGPLVLPLIA
     VFVIIATEAI GDITASCDVS RIPFEGDVYE SRIQGGLLTD GLISVAAGLM TMTPTSRFAQ
     NNGVIALTRC ANRKAGYACC FFLIMMGIFA KFAASLVAIP SSVLGGMTTF LFAAVAVSGM
     AIIYRGNSFD RRTRFILTAG LAMGYGATLV PNWFSNVFSY AGDNTALLGL LDAITLIMQT
     GFAVAAAVCM ALNLTLPDEV DDDVVTTEHI SSDSSCKQQG VVINELEEST TVT
//