ID   A0A1B8FF46_9PEZI        Unreviewed;       908 AA.
AC   A0A1B8FF46;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN   ORFNames=VE02_09185 {ECO:0000313|EMBL:OBT82169.1};
OS   Pseudogymnoascus sp. 03VT05.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1622148 {ECO:0000313|EMBL:OBT82169.1};
RN   [1] {ECO:0000313|EMBL:OBT82169.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=03VT05 {ECO:0000313|EMBL:OBT82169.1};
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT   white-nose syndrome of bats.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KV459599; OBT82169.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1B8FF46; -.
DR   Proteomes; UP000091872; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR   Gene3D; 2.30.30.60; -; 1.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR010920; LSM_dom_sf.
DR   InterPro; IPR023408; MscS_beta-dom_sf.
DR   InterPro; IPR006685; MscS_channel_2nd.
DR   PANTHER; PTHR31323; MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2; 1.
DR   PANTHER; PTHR31323:SF1; MECHANOSENSITIVE ION CHANNEL PROTEIN MSY2; 1.
DR   Pfam; PF00924; MS_channel_2nd; 1.
DR   SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        153..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        235..253
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        465..486
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        498..520
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          409..444
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   REGION          58..96
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          702..737
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          751..777
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          808..908
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        845..880
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   908 AA;  98879 MW;  7A65244E1650DDA9 CRC64;
     MSYQSGITSA RQGGFIPLSN AASKETLRNN DAMNFEDIPM TKVKSNASSA WQQRDGQSIY
     GNDADATGSR LAPPDDHGHH GRRKLKKMNS RQSNATNQQS VLTGMGKFYD KIVNFSIVTR
     YLVYVLPIAA LIAIPIVIGA TVAPDAKIGG IRLLWFFVWI ECVWLSIWIA KLFAKTVPYC
     FVFLCGVISP GTRKYALILR RLEIPLSLVG WAVASIATFE ALIKRPDNSP QHWTAIMKKI
     LAAALIAACI YLVEKLIIQL ISISYHSRSF DLRIQESKHQ THLLGLLYDA SRALFPLYCP
     EFAEEDYRIT GNVDIIRVGK KASGAATPMR LMGNVNRIGD KITSAFGNVA SEITGKKVFN
     PNSAHSIVLH ALEKKKSSEA LAKRLWMSFV IEGKEALGIE DIREVLGPAH KDEADEAFAY
     IDADDNGDIS LDEMIVKVVA MSRERKAIAN SMHDIGDAIS VLDSVLVAVA FVIIIFIFVA
     FLNASFVTTL ATAGTTLLSL SFIFMVTCQE FLGSCVFLFI KHPYDVGDRV DINNEPLIVE
     RISLLYTIFK RIDYMKMVQV PNIVLNNMWI ENVTRSKAMK EQIELSISFD TSLEDIELLR
     TELEAFVRHP DNSRDFQEDV VLECAGVGTM DKLVLKAEIR HKSNWANESI RASRRSKFMC
     ALVLAVRKVP IYGPGGGGPA LGEPGNPSYS VAVSDDLAAE ARAKAAEANE AKRLVPTSKP
     DAGKSTEPGA TAPESGVLGA THETAAAAAM NARRPTDTGL DTQQRGRGDT LGRARSSDIE
     DLRNDLLHRA STRGRRRADM TAFPLQVGTS GASIGLTPSS PLRDSADEDE EAKVGGYGGY
     SASPGYPVQA QQQQGVGFPA QAQGMQGQTY PTQQQGPGGS YAQFPAGAAG QGQLGQQPAP
     PRKDGARF
//