ID   A0A1B8FJV0_9PEZI        Unreviewed;       520 AA.
AC   A0A1B8FJV0;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=sphingolipid C(9)-methyltransferase {ECO:0000256|ARBA:ARBA00039020};
DE            EC=2.1.1.317 {ECO:0000256|ARBA:ARBA00039020};
GN   ORFNames=VE02_06133 {ECO:0000313|EMBL:OBT83874.1};
OS   Pseudogymnoascus sp. 03VT05.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1622148 {ECO:0000313|EMBL:OBT83874.1};
RN   [1] {ECO:0000313|EMBL:OBT83874.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=03VT05 {ECO:0000313|EMBL:OBT83874.1};
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT   white-nose syndrome of bats.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Lipid metabolism; sphingolipid metabolism.
CC       {ECO:0000256|ARBA:ARBA00004760}.
CC   -!- PATHWAY: Sphingolipid metabolism. {ECO:0000256|ARBA:ARBA00004991}.
CC   -!- SIMILARITY: Belongs to the CFA/CMAS family.
CC       {ECO:0000256|ARBA:ARBA00010815}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KV459498; OBT83874.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1B8FJV0; -.
DR   Proteomes; UP000091872; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR45197:SF1; SPHINGOLIPID C9-METHYLTRANSFERASE A-RELATED; 1.
DR   PANTHER; PTHR45197; SYNTHASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_7G04190)-RELATED; 1.
DR   Pfam; PF02353; CMAS; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        59..78
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        87..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   520 AA;  59016 MW;  07E94E0EBF9E7E94 CRC64;
     MASKPPQTTS SSESDFEFIE TPKVHTPTFE KFEECGVKTT AYPAIKNAPL PADGPGSESF
     SNIALFSLLF IVPAYTAWKV GGGLKTTIFF GLFTSIPLLI SFWYLNSTLG PRKNEKVRLP
     GRPIEHYLTF KNDADKLKYR GRTKIPMETF HNMYFEGDVE FNGDCLEVLE YRADWASFTF
     TISLFKFIFF QFAPEVIMHT RSQDEEQVRD HYDRGDDFYG WFLGPRMIYT SGIISDITKE
     ETLEELQDNK LAIVCEKIDL QKDERMLDIG CGWGTLAKFA SVNFGAQVTG ITLGRNQTAW
     GNNGLRKAGI TEEQSRILCM DYRDIPVPEG KYNKITCLEM AEHVGVRHFK TFLKQVNDML
     DDDGVFFLQI AGLRKSWQYE DLMWGLFMNR YVFPGADAST PLGFFVDSLE GAGFEVKSVD
     TVGVHYSATL WRWYRNWLGN RDKVEAKYGS RWFKIWEFFL AYSTIISREG GATCYQLTLV
     KNINSTHRVE GIATQFALTA ALAKGRADIE ANAAANGVKA
//