ID   A0A1B8FQA1_9PEZI        Unreviewed;       958 AA.
AC   A0A1B8FQA1;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=alpha-L-rhamnosidase {ECO:0000256|ARBA:ARBA00012652};
DE            EC=3.2.1.40 {ECO:0000256|ARBA:ARBA00012652};
GN   ORFNames=VE02_05223 {ECO:0000313|EMBL:OBT85730.1};
OS   Pseudogymnoascus sp. 03VT05.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1622148 {ECO:0000313|EMBL:OBT85730.1};
RN   [1] {ECO:0000313|EMBL:OBT85730.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=03VT05 {ECO:0000313|EMBL:OBT85730.1};
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT   white-nose syndrome of bats.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal non-reducing alpha-L-rhamnose residues
CC         in alpha-L-rhamnosides.; EC=3.2.1.40;
CC         Evidence={ECO:0000256|ARBA:ARBA00001445};
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DR   EMBL; KV459439; OBT85730.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1B8FQA1; -.
DR   Proteomes; UP000091872; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 1.50.10.10; -; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 2.60.420.10; Maltose phosphorylase, domain 3; 1.
DR   InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR   InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR   InterPro; IPR035396; Bac_rhamnosid6H.
DR   InterPro; IPR035398; Bac_rhamnosid_C.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   PANTHER; PTHR34987:SF5; ALPHA-RHAMNOSIDASE; 1.
DR   PANTHER; PTHR34987; C, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G02880)-RELATED; 1.
DR   Pfam; PF17389; Bac_rhamnosid6H; 1.
DR   Pfam; PF17390; Bac_rhamnosid_C; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          218..331
FT                   /note="F5/8 type C"
FT                   /evidence="ECO:0000259|Pfam:PF00754"
FT   DOMAIN          524..732
FT                   /note="Alpha-L-rhamnosidase six-hairpin glycosidase"
FT                   /evidence="ECO:0000259|Pfam:PF17389"
FT   DOMAIN          846..920
FT                   /note="Alpha-L-rhamnosidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17390"
FT   REGION          18..41
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          191..226
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        201..226
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   958 AA;  103962 MW;  0EF1F04C0B3AA496 CRC64;
     MGHNRRYHRC FYRRRTVSSK VPRDSAPSKY APSRRHRPSR PKNLELEGLD YAYDHAASQC
     LSITPSKPAI VTVEWADCDM DLKSHVNIPV GYQVIKEEDP ALRVESRGPV RKAMAQIALQ
     RWWALALLVL INAVPYIQGQ QSPSWAQYII SPQSLTVLPT AILEDRTVGD VTNPSALLAS
     GGDVTTLKRA APVAPPSWPE GTTADASSFH PENQNNGQTR TYTPSNAIDG NEATFWNDDT
     VSAYPDILTL TIPTASTLSG ITILSSSDGV PVKFTVEALQ GGSWGAVATV SDNAAVLIQV
     PFAAPVNAEG IRITVTQAQA TGQGEYTRIA EVWPGIVPGQ AAPAVVLDFG KVVVGKLSIK
     FAGASTNNPG IRLAFSETTQ YLTDLSDFSR SNNGDTITPG SDQIAIKADP YTWTDNHGCE
     DGTKVCADGL HGFRYVKIYL DALAADAPNT EASGSVSIDS VSLAFSAYLG TEDTYSGNFE
     CSDAALNEFW YAAVYTNDLC TDTFRLEDTE PRNAGSPTLV GKEVLFDGAK RDRDPYVGDL
     AVAARTLYLT HNFSIAAENV LADLADHQRS DGWIPPASIN DYQLQLLDYP LHWVTCTYDL
     IVYTSSDAYA AKYYPTIIKV LDNFYPSMTD SATGLINKPD DSPYGDYAFL NRHGLITYYN
     ALYVQALRNA ASIATFYNHP DDAKRWTERA QTVSDAINAH LWDASVGAYF DSSKNNNHGQ
     DGNGLAVLNG IADSTRSASA LKYWASLALP YGNPFFDSDV IGGGFSKRVY AFISYFELQA
     RFASGAGDSA IEEIKRLYGW MATHDPKSTF WEGIGTDGSM YEAGYTSATH GWSTGIVPLM
     SNYVLGILPT APAFTEWTVK PMLVGGITWA KGQVDTPHGP LVVDWTTENA SSQFQITVTV
     PKGTKGTVSV PVTSEKVMVA VDSKLVYAVG RRAFNPKYKD GHVTVQLEDG KHVITASK
//