ID   A0A1B8FTX2_9PEZI        Unreviewed;       433 AA.
AC   A0A1B8FTX2;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Saccharopine dehydrogenase {ECO:0000313|EMBL:OBT87035.1};
GN   ORFNames=VE02_03687 {ECO:0000313|EMBL:OBT87035.1};
OS   Pseudogymnoascus sp. 03VT05.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1622148 {ECO:0000313|EMBL:OBT87035.1};
RN   [1] {ECO:0000313|EMBL:OBT87035.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=03VT05 {ECO:0000313|EMBL:OBT87035.1};
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT   white-nose syndrome of bats.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the saccharopine dehydrogenase family.
CC       {ECO:0000256|ARBA:ARBA00038048}.
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DR   EMBL; KV459410; OBT87035.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1B8FTX2; -.
DR   Proteomes; UP000091872; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR005097; Sacchrp_dh_NADP.
DR   PANTHER; PTHR12286:SF5; SACCHAROPINE DEHYDROGENASE-LIKE OXIDOREDUCTASE; 1.
DR   PANTHER; PTHR12286; UNCHARACTERIZED; 1.
DR   Pfam; PF03435; Sacchrp_dh_NADP; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        281..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        372..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          8..137
FT                   /note="Saccharopine dehydrogenase NADP binding"
FT                   /evidence="ECO:0000259|Pfam:PF03435"
SQ   SEQUENCE   433 AA;  47727 MW;  D2F25F582BB10262 CRC64;
     MSTRQYDIVL WGATGYTGWW TAKHIARSYP TDIRWAIAGR SESKLKAVAE SCAKINPDRV
     QPSIEICNLD EAELADLARK TTVLIATVGP FCVYGEPALK ACAENGTHYL DITGEIPWVM
     SMVKKYEKVA KSTGAVLISQ SAVESLPSDL VAYAIVKRIH QELSTTTREV IFSVEDIKST
     FSGGTLHSIL EVVDRFSIPD LRRIKKPFIH SPIPGPTAPT TQSAWTNILG VREHPDLGIL
     TTYFGASSDV PIVERSWGLI GNGKVYGPNF RFSEYARARS IFLALFIHFV LTVGTILLKF
     PFATSAMRKV IPPRGYGASE EETKSHFVEY RAVGRPNADT LTRAHARVRY TGGLYESKHS
     NLASFVLRTR RIMAIMLMSG LLVSQAALTL LKDDVTAKKL GGGFMTPATL GQPLIDRLAD
     LGFKIEVKMV ETE
//