ID   A0A1B8FU08_9PEZI        Unreviewed;       735 AA.
AC   A0A1B8FU08;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=beta-glucosidase {ECO:0000256|ARBA:ARBA00012744};
DE            EC=3.2.1.21 {ECO:0000256|ARBA:ARBA00012744};
GN   ORFNames=VE02_05029 {ECO:0000313|EMBL:OBT87077.1};
OS   Pseudogymnoascus sp. 03VT05.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1622148 {ECO:0000313|EMBL:OBT87077.1};
RN   [1] {ECO:0000313|EMBL:OBT87077.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=03VT05 {ECO:0000313|EMBL:OBT87077.1};
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT   white-nose syndrome of bats.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of terminal, non-reducing beta-D-glucosyl residues
CC         with release of beta-D-glucose.; EC=3.2.1.21;
CC         Evidence={ECO:0000256|ARBA:ARBA00000448};
CC   -!- PATHWAY: Glycan metabolism; cellulose degradation.
CC       {ECO:0000256|ARBA:ARBA00004987}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 3 family.
CC       {ECO:0000256|ARBA:ARBA00005336}.
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DR   EMBL; KV459409; OBT87077.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1B8FU08; -.
DR   Proteomes; UP000091872; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1700; Glycoside hydrolase family 3 C-terminal domain; 1.
DR   Gene3D; 3.20.20.300; Glycoside hydrolase, family 3, N-terminal domain; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR026891; Fn3-like.
DR   InterPro; IPR002772; Glyco_hydro_3_C.
DR   InterPro; IPR036881; Glyco_hydro_3_C_sf.
DR   InterPro; IPR001764; Glyco_hydro_3_N.
DR   InterPro; IPR036962; Glyco_hydro_3_N_sf.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR42715; BETA-GLUCOSIDASE; 1.
DR   PANTHER; PTHR42715:SF29; BETA-GLUCOSIDASE L-RELATED; 1.
DR   Pfam; PF14310; Fn3-like; 1.
DR   Pfam; PF00933; Glyco_hydro_3; 1.
DR   Pfam; PF01915; Glyco_hydro_3_C; 1.
DR   PRINTS; PR00133; GLHYDRLASE3.
DR   SMART; SM01217; Fn3_like; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF52279; Beta-D-glucan exohydrolase, C-terminal domain; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           21..735
FT                   /note="beta-glucosidase"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5008608039"
FT   DOMAIN          656..726
FT                   /note="Fibronectin type III-like"
FT                   /evidence="ECO:0000259|SMART:SM01217"
SQ   SEQUENCE   735 AA;  77080 MW;  6185E46150157099 CRC64;
     MAFLKSATLA LAALLPLTSA VPTARADDGG WDAAHAKAVT ALAKLSLGDK VKMVTGEGWE
     KGPCVGTTAE ISSIGYPQLC LQDGPLGIRF AQGITAFPAG VQAASTWDIA LIKARGNALG
     TESKAMGVHV QLGPVGGPLG KIPHGGRNWE GFSPDPYLTG VAMAETITGM QNAGVQACAK
     HYIGNEQELN RDTMSSTIAD RVNHELYLWP FADSVKANVA AVMCSYNRLN GTYACESDLA
     LNGLLKGELD FRGYVVSDWN AQHTTVGSAK AGMDMSMPGD NFGDNNYLWG TALTNAVSGG
     QVDESRVDDM VERILASWYY LGQDAGYPKV GWSSWNGGVG GPEVQGEHKI VARDIARDGI
     VLLKNENNAL PLKKPASLAI IGNDAINNPN GPNACVDRGC DVGTLAMGWG SGAAEFPYLI
     SPLDAIQKQA TADGTTIVSS TTDSTSEGAA AAGKADTALV FINADSGEGY ITVEGQAGDR
     ADLDPWHNGN GLVEAVANVN KNTIVVIHSV GPLILEKILA LPNVVAVVWA GLPGQESGNG
     LVDILYGSKS PSGKLPYTIA KQASDYGTSV RSGDDDFSEG LYIDYRHFDQ AGIEPRYEFG
     FGLSYTTFGY SDLTTTYTDK TEGSTTTAPG GAEGLYDTVV TVTAKITNSG TVEGAEVAQL
     YIGLPSTAPP TPVRQLRGFS KINLAAGESG TVTFNLRRKD LSYWDTDAQK WVTPTGDFTV
     SVGASSRNLA LKGTM
//