ID   A0A1B8G5J5_9PEZI        Unreviewed;      1008 AA.
AC   A0A1B8G5J5;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=SPX domain-containing protein {ECO:0000259|PROSITE:PS51382};
GN   ORFNames=VE02_00107 {ECO:0000313|EMBL:OBT91109.1};
OS   Pseudogymnoascus sp. 03VT05.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1622148 {ECO:0000313|EMBL:OBT91109.1};
RN   [1] {ECO:0000313|EMBL:OBT91109.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=03VT05 {ECO:0000313|EMBL:OBT91109.1};
RA   Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT   "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT   white-nose syndrome of bats.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; KV459351; OBT91109.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A1B8G5J5; -.
DR   Proteomes; UP000091872; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd01115; SLC13_permease; 1.
DR   CDD; cd14478; SPX_PHO87_PHO90_like; 1.
DR   InterPro; IPR004680; Cit_transptr-like_dom.
DR   InterPro; IPR001898; SLC13A/DASS.
DR   InterPro; IPR004331; SPX_dom.
DR   NCBIfam; TIGR00785; dass; 1.
DR   PANTHER; PTHR10283:SF92; LOW-AFFINITY PHOSPHATE TRANSPORTER PHO91; 1.
DR   PANTHER; PTHR10283; SOLUTE CARRIER FAMILY 13 MEMBER; 1.
DR   Pfam; PF03600; CitMHS; 1.
DR   Pfam; PF03105; SPX; 2.
DR   PROSITE; PS51382; SPX; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        538..561
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        573..606
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        626..651
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        672..700
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        712..731
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        752..778
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        798..816
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        823..845
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        851..870
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        890..919
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        939..963
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        984..1005
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          158..421
FT                   /note="SPX"
FT                   /evidence="ECO:0000259|PROSITE:PS51382"
FT   REGION          26..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          87..110
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          260..341
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        260..279
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        280..298
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        312..326
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1008 AA;  111468 MW;  93B309A5C8E092AF CRC64;
     MSDSRKVTAT STITQSRTSD ALIYSNRQIL KSPPPCPIPD TGLQRIIPAD SSTGKKATSR
     LREHETEALD PLSPKIAKLA TGGIVPPLSA RTYTEKNNSG DRNENQRHND EGQSDVYELT
     DFNNPPNHTT DDDFEAREAR RLAKRVEKLA RREEEFEMKF SHSIQFNAVP DWSSHYIAYS
     NLKKLIYQLE KNQNRQNAPT TDAEASPLLA GNVDPDQIFT RALDVELEKI SSFYQIKELE
     IFSEISELLS RREEYDAELQ ENGMEGSSEV HDHPRRPSSF YRGNTRNVRP ASTTTRSMTD
     DVDDSDEDDD EETALNRRKP EVRRSMTAPS DVDGSHGGEE MWNSTAELNR RSSVAAYDDY
     ADEAFSLYYS SGISLKKNTV SLYVQLCELK SFIQLNQTGF RKVLKKYDKI LDRNLREKYM
     SQTVAASYVF RPSTIKHVEE NIGRMENIYA DVVTAGDLTL AKKELRLHLR EHVVWERNTV
     WREMIGIERK AQAANMGIRR TLLGADTDPT HARLQGDDEG VADLKGINTP VGRMYYPAWL
     FSSTMLVLLL IITIFTLLLI IPIMANPEQQ NCLAMLVFVS LLWATEVIPL FVTSLLIPFL
     CVLLRVVRSD DAPHHRLGAK PAAAYIFAAM WTPVIMLLLG GFTIAAALSK YDIAKRIATI
     VLSKAGTRPR TVLVTNMFVA AFASMWISNV AAPVLCFSII QPMLRNLPSD SNMSKALILG
     IALASNVGGM LSPIASPQNI IALAIMSPQP SWAVWFFIAI PVGIISILLI WILLLVSFKP
     GKGTTIVPVR TVRDPFSGIQ WFISLVTLAT IILWCVSHQL EHVLGDMGVV AIIPLVLFFG
     TGILTKEDFN NFLWTIIILA AGGLALGKAV NSSGLLHTIA ASITDAVEGL SLYSVLVVFA
     SLILVVATFI SHTVAALIIL PLVHSVGVGM ENPHPNLLVM GGALMCSAAM GLPTSGFPNM
     TAIMMEDSQT GQRYLQVKHF ISRGVPSSVL TLLVVITVGY GAMLISNI
//