ID A0A1B8GD53_9PEZI Unreviewed; 518 AA.
AC A0A1B8GD53;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 23-MAY-2018, sequence version 2.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=G-protein coupled receptors family 2 profile 2 domain-containing protein {ECO:0000259|PROSITE:PS50261};
GN ORFNames=VE01_08171 {ECO:0000313|EMBL:OBT93764.2};
OS Pseudogymnoascus verrucosus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=342668 {ECO:0000313|EMBL:OBT93764.2, ECO:0000313|Proteomes:UP000091956};
RN [1] {ECO:0000313|EMBL:OBT93764.2, ECO:0000313|Proteomes:UP000091956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 10579 {ECO:0000313|EMBL:OBT93764.2,
RC ECO:0000313|Proteomes:UP000091956};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 10579 {ECO:0000313|Proteomes:UP000091956};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KV460250; OBT93764.2; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8GD53; -.
DR STRING; 342668.A0A1B8GD53; -.
DR OrthoDB; 20196at2759; -.
DR Proteomes; UP000091956; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR GO; GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR017981; GPCR_2-like_7TM.
DR InterPro; IPR000832; GPCR_2_secretin-like.
DR PANTHER; PTHR42058:SF1; -; 1.
DR PANTHER; PTHR42058; G_PROTEIN_RECEP_F2_4 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00002; 7tm_2; 1.
DR PROSITE; PS50261; G_PROTEIN_RECEP_F2_4; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000091956};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT DOMAIN 62..226
FT /note="G-protein coupled receptors family 2 profile 2"
FT /evidence="ECO:0000259|PROSITE:PS50261"
FT REGION 439..518
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 449..463
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 518 AA; 56333 MW; 2983C572A7C767A8 CRC64;
MVYNATLDAA FRGNCFAPFL QEELYVNITT GYIPGRICTE LAPNITCCLP CPSTDWLYPD
SFQTVTNASS WLNVVGLVCT VFLLLSFAVL PVEKTHRHYL SICLVIAVVI MQLGFVIPLG
AKPEQCANAI TPHGMESSIT CALSGAFLLA GGWCGIMWVF MRALALHLQI CWQVVIGKAF
MWGALAGGWG VPAVALAIAM VFSGVSFRFG ETCHINHTNS LADFWIPLLI FAGLTVIIQF
TTFGYCIKVY LASLSDSSST TNSSALPSYS GSVVTLTPRQ AYRRVQRVVE LQWRGIAIVL
IIITDVIFFA VVFVVMDNNQ IKAANVSLLD ATAGGETSPS VEWLLCLVTN AGKKGPCLEK
SADLIMNQAT ITAVLVLLSC NGIWLLLLMS RLSMFTGWYD LVRSKAKPSG EFISADAARA
YSKDPSTYEM LASNGRDVEY PSKPDLPLTQ LSPAVTSPVG RSGRQTPDYF GREAKYQNPT
HSFSSPRPPP GGRDWNSATT HAPSAHQPHL DPLSMNKF
//
