ID A0A1B8GH78_9PEZI Unreviewed; 625 AA.
AC A0A1B8GH78;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE RecName: Full=DNA polymerase kappa {ECO:0000256|ARBA:ARBA00016178};
GN ORFNames=VE01_07561 {ECO:0000313|EMBL:OBT95175.1};
OS Pseudogymnoascus verrucosus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=342668 {ECO:0000313|EMBL:OBT95175.1, ECO:0000313|Proteomes:UP000091956};
RN [1] {ECO:0000313|EMBL:OBT95175.1, ECO:0000313|Proteomes:UP000091956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 10579 {ECO:0000313|EMBL:OBT95175.1,
RC ECO:0000313|Proteomes:UP000091956};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 10579 {ECO:0000313|Proteomes:UP000091956};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
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DR EMBL; KV460237; OBT95175.1; -; Genomic_DNA.
DR RefSeq; XP_018128908.1; XM_018276995.1.
DR AlphaFoldDB; A0A1B8GH78; -.
DR STRING; 342668.A0A1B8GH78; -.
DR GeneID; 28840947; -.
DR OrthoDB; 146204at2759; -.
DR Proteomes; UP000091956; Unassembled WGS sequence.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0070987; P:error-free translesion synthesis; IEA:UniProt.
DR CDD; cd03586; PolY_Pol_IV_kappa; 1.
DR Gene3D; 1.10.150.810; -; 1.
DR Gene3D; 3.30.70.270; -; 2.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR022880; DNApol_IV.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076:SF33; DNA POLYMERASE KAPPA; 1.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000091956}.
FT DOMAIN 110..289
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 459..497
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 524..543
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 582..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 358..385
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 596..617
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 625 AA; 70165 MW; 51CF5F24CD41F75F CRC64;
MTANPNTLEH DDQETNLHDT LKYSLLGPSL TKSGQDSVDQ KKVSDIIYDA SKGSKFFTHE
ENRDKLLTVK IEKILEKKAR LEKLNLTRDQ KKADEYVAEL ELSRDLSQTI VHVDCDAFYA
AVEELDRPEL KQVPFAVGKG VLTTCNYHAR KFGCRSGMAG FVARKLCPEL IQLPLNFEKY
TAKAREVREI IARYDPRFES ASIDEAYLNI TSYCESNNIV PDEAVEQLRQ EVHDKTKITI
SAGIAANTKL AKICSNMNKP NGQYRLQNDR GAIMAFMDTL PTRKVNGVGR VFERELDAVG
VKTCGDIYQY RQYLSKLFGE KAFNFLIHCY LGLGRTDTQP AEEYERKSVG TESTFGDLSS
HKGLRDKLEK TAQDLEKDMI KAQVKGRTLV LKVKLHTYEV LTRQIIPPKA VYLAPDLYRY
SLPMLSKLEQ EFKGLTLRLM GLRCTHLITM KKPDSLAFFG HPKMRNSPAS SGPASGTNES
KEEPLEAGGT SSLGAWPGED FEEAAKDEYQ EELEELEILS QLEELGNQQP SGGSLDTETK
PESEDRWWDC PICLRPQMGD CNEHIDMCLS RPTILGLVKE AAREASSASA SAEKGKGLSK
RGRQDSGKSR TGLKDDPKQT RLSFN
//
