ID A0A1B8GPF3_9PEZI Unreviewed; 1542 AA.
AC A0A1B8GPF3;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=ABC transporter domain-containing protein {ECO:0000259|PROSITE:PS50893};
GN ORFNames=VE01_05043 {ECO:0000313|EMBL:OBT97725.1};
OS Pseudogymnoascus verrucosus.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=342668 {ECO:0000313|EMBL:OBT97725.1, ECO:0000313|Proteomes:UP000091956};
RN [1] {ECO:0000313|EMBL:OBT97725.1, ECO:0000313|Proteomes:UP000091956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 10579 {ECO:0000313|EMBL:OBT97725.1,
RC ECO:0000313|Proteomes:UP000091956};
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Comparative genomics of Pseudogymnoascus destructans, the fungus causing
RT white-nose syndrome of bats.";
RL Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000091956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UAMH 10579 {ECO:0000313|Proteomes:UP000091956};
RX PubMed=29295979; DOI=10.1038/s41467-017-02441-z;
RA Palmer J.M., Drees K.P., Foster J.T., Lindner D.L.;
RT "Extreme sensitivity to ultraviolet light in the fungal pathogen causing
RT white-nose syndrome of bats.";
RL Nat. Commun. 9:35-35(2018).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
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DR EMBL; KV460220; OBT97725.1; -; Genomic_DNA.
DR RefSeq; XP_018131458.1; XM_018274509.1.
DR STRING; 342668.A0A1B8GPF3; -.
DR GeneID; 28838429; -.
DR OrthoDB; 5473955at2759; -.
DR Proteomes; UP000091956; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03233; ABCG_PDR_domain1; 1.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR029481; ABC_trans_N.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034001; ABCG_PDR_1.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010929; PDR_CDR_ABC.
DR PANTHER; PTHR19241; ATP-BINDING CASSETTE TRANSPORTER; 1.
DR PANTHER; PTHR19241:SF625; ATP-DEPENDENT PERMEASE PDR10-RELATED; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF14510; ABC_trans_N; 1.
DR Pfam; PF06422; PDR_CDR; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000091956};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 508..531
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 543..565
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 619..639
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 651..670
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 756..777
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1181..1200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1212..1235
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1255..1281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1301..1321
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1333..1354
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1452..1473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 144..398
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 844..1086
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 25..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1479..1542
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1480..1494
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1512..1526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1542 AA; 171609 MW; 7C872293A9B485A8 CRC64;
MATAPVPGAF GVLPEAQGVT TNAIGHSIES ERPVTEDTLH DETDTSSSEN NEKHITDLAR
TFTQASIRNE QGEHDNPFTS ADPTLDPHNE KFNARAWTKT LVGITSRDPE RYPTRTAGIA
YKNLNVHGFG NPMDYQKTFG NYPLEIGGLF NKLRGKGQRK IQILRNFEGL VRSGEMLVVL
GRPGSGCSTL LKTISGETNG FFIDQESTIN YQGIAAQQMH NDFRGECIYQ AEVDVHFPQL
TVGQTLKFAA LARAPNNRIP GVSREQYAEH MRDVVMAMFG LSHTINTNVG NDYIRGVSGG
ERKRVSIAEC CVGQSPLQCW DNSTRGLDSA TALEFVKTLR LSTNISGATA IVAIYQASQS
IYDVFDKVAV LYEGRQIYFG HKHKAKEFFV NMGFDCPERQ TTADFLTSLT SPLERIVRPG
FEHSTPKTPD EFADAWQKSA DRAQLLREIE EFEAEYPIGG AHLEKFKEGR RAQQARGQRI
KSPYTISVPM QVKLCVTRGF QRLRGDMSLL FAGIFGNTVM ALVIASVFFN LQDNTETLFS
KGALLFFAIL INAFSSALEI LTLFAQRPIV EKHTKYAFYH PFAEAIASMI CDMPNKIGSS
IFFNITLYFM TNLKRTPSAF FTFILFGFSC VMAMSMFFRS IGSMARSLPE ALGPAAVIIL
SLIIYTGFTI PTVDMHPWFR WINYIDPVAY AFESLMVNEF SGRKIPCTSF VPRGGDYDLL
TLANKVCVTT GAEAGSDVLD GDVWLRVNYG YERSHMWRNL GILWALVVFG CAVHLLATEW
ISAKKSKGEV LLFPRGKVPE LASASNDEEG AQDNRIDTNT LEATATHAAA GEAPPSIQRQ
TAVFHWQGVN YDIKIKKEPR RLLDDVDGWV KPGTLTALMG VSGAGKTTLL DVLASRVTMG
VVTGQMLVDG RQRDSGFQRK TGYVQQQDLH LATSTVREAL TFSALLRQPK ATPRAEKIAY
VDEVIKVLEM ETYAEAVVGV PGEGLNVEQR KRLTIGVELA AKPALLLFLD EPTSGLDSQT
AWSIIALLRK LANNGQAILC TIHQPSAILF QEFDRLLFLA KGGRTVYFGD VGQNSSILTD
YFVRNGARPC GVEENPAEWM LEVIGAAPGS TTTVDWPVAW NESDEKAEVR AQLADMRRQL
IEKEVETDPT SLDEYAAPMG QQLGTVTQRV FQQFWRTPSY LYSKTFLCVS TGLFIGFSFW
DAPTSMQGIQ NQLFSIFMLL TIFGNLVQQM MPHFVTQRSL YEVRERPSKT YSWKVFIVSN
IIVELPWNSL MSVLLFATYY YPIGMYRNAQ HAGQFHERGG LMFLYIWSFL MFTSTFSTMI
IAGMETAEAG GNIANLLFSL CLIFCGVLAS PQVMPRFWIF MYHLSPFRYL VDGMLAVGIA
NVDVVCQARE ILHLNPTVGK TCTQFMGAFV ELAGGYLVNG DATTDCQYCS VGKSNDLLKV
FSSSYAHRWR NFGILQGYVF FNAGMAVFIY WLARVPKNSG KEEPPTEEEL ALQKSRTRNS
TTAAGGLEKT ATRDSARGKR RTWGSRGENK LATTEEIVAE KQ
//
