ID A0A1B8J6H9_9HELI Unreviewed; 425 AA.
AC A0A1B8J6H9;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Sodium:proton antiporter {ECO:0000313|EMBL:OBV28560.1};
GN ORFNames=BA723_09000 {ECO:0000313|EMBL:OBV28560.1}, BKN38_01165
GN {ECO:0000313|EMBL:OHU85677.1};
OS Helicobacter sp. CLO-3.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=211 {ECO:0000313|EMBL:OBV28560.1, ECO:0000313|Proteomes:UP000092701};
RN [1] {ECO:0000313|EMBL:OBV28560.1, ECO:0000313|Proteomes:UP000092701}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HMC1 {ECO:0000313|EMBL:OBV28560.1,
RC ECO:0000313|Proteomes:UP000092701};
RA Greninger A.L., Bateman A., Jerome K., Fang F.;
RT "Genome sequence of Helicobacter sp. CLO-3.";
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OHU85677.1, ECO:0000313|Proteomes:UP000179541}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLO-3 {ECO:0000313|EMBL:OHU85677.1,
RC ECO:0000313|Proteomes:UP000179541};
RA Greninger A.L., Bateman A.C., Fang F., Jerome K.;
RT "Genome sequence of Helicobacter sp. CLO-3 Fennel-37 strain.";
RL Submitted (OCT-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBV28560.1}.
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DR EMBL; MAMQ01000110; OBV28560.1; -; Genomic_DNA.
DR EMBL; MLQN01000002; OHU85677.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8J6H9; -.
DR STRING; 211.BKN38_01165; -.
DR Proteomes; UP000092701; Unassembled WGS sequence.
DR Proteomes; UP000179541; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR InterPro; IPR018461; Na/H_Antiport_NhaC-like_C.
DR InterPro; IPR032813; Na_H_antiport_N.
DR PANTHER; PTHR37821; AMINO ACID TRANSPORTER YUIF-RELATED; 1.
DR PANTHER; PTHR37821:SF1; AMINO ACID TRANSPORTER YUIF-RELATED; 1.
DR Pfam; PF13726; Na_H_antiport_2; 1.
DR Pfam; PF03553; Na_H_antiporter; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092701};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..425
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5010465129"
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..97
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..241
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 247..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 342..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..77
FT /note="Putative Na+/H+ antiporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13726"
FT DOMAIN 136..418
FT /note="Na+/H+ antiporter NhaC-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03553"
SQ SEQUENCE 425 AA; 44826 MW; EB906EF9F53343C0 CRC64;
MCALCLVRCN VLIALFASAL IAGVISGASV DDTLNTLIKG MSSNLEIALS YILLGFLAAA
IAKSNIIALA IHKLTHILSH RLFGSSVLFC LIIAAFACLS QNLIPVHIAF IPILIPPLLG
IMNMMKLDRR AIACALTFGL KAPYITLPVG YGLFFHQTII KEMNKNGFSI TLDDTSGVLW
IGGVAMLLGL IIAVVAFCAR PREYRERAIE MQENRIKHTK IGFSDISIIV GAFVAFGIQI
YTSSMPLGAF AGIVIMLLGR GILWRDMDNI VDDGIKLMGF IAFVMLLAAG FGEVLKSSGA
VDELIRICSL VVGGKLGGAV LMLVLGLLIT MGIGSSFGTI SIIATFYCPL CMELGFGVES
SILLVGIAAA LGDAGSPASD STMGPTSGLN ADGEHDHIWD TCVPTFLAFN VPLLIAGVIG
AMILG
//
