ID   A0A1B8SJ64_9MYCO        Unreviewed;       691 AA.
AC   A0A1B8SJ64;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=VWA domain-containing protein {ECO:0000313|EMBL:NDJ87683.1};
GN   ORFNames=ACT18_04865 {ECO:0000313|EMBL:OBY32771.1}, BST28_11915
GN   {ECO:0000313|EMBL:ORA79534.1}, GWR20_00705
GN   {ECO:0000313|EMBL:NDJ87683.1};
OS   Mycolicibacter kumamotonensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC   Mycolicibacter.
OX   NCBI_TaxID=354243 {ECO:0000313|EMBL:OBY32771.1, ECO:0000313|Proteomes:UP000092668};
RN   [1] {ECO:0000313|EMBL:OBY32771.1, ECO:0000313|Proteomes:UP000092668}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Roo {ECO:0000313|EMBL:OBY32771.1,
RC   ECO:0000313|Proteomes:UP000092668};
RA   Greninger A.L., Cunningham G., Miller S.;
RT   "Genome sequence of Mycobacterium kumamotonense strain Roo.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ORA79534.1, ECO:0000313|Proteomes:UP000192713}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45093 {ECO:0000313|EMBL:ORA79534.1,
RC   ECO:0000313|Proteomes:UP000192713};
RA   Tortoli E., Trovato A., Cirillo D.M.;
RT   "The new phylogeny of genus Mycobacterium.";
RL   Submitted (FEB-2017) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:NDJ87683.1, ECO:0000313|Proteomes:UP000466523}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CST 7247 {ECO:0000313|EMBL:NDJ87683.1,
RC   ECO:0000313|Proteomes:UP000466523};
RA   Sanchez-Estrada R., Gonzalez-Y-Merchand J.A., Rivera-Gutierrez S.;
RL   Submitted (JAN-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OBY32771.1}.
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DR   EMBL; JAACYR010000002; NDJ87683.1; -; Genomic_DNA.
DR   EMBL; LFOE01000004; OBY32771.1; -; Genomic_DNA.
DR   EMBL; MVHU01000015; ORA79534.1; -; Genomic_DNA.
DR   RefSeq; WP_065287314.1; NZ_MVHU01000015.1.
DR   AlphaFoldDB; A0A1B8SJ64; -.
DR   STRING; 354243.BST28_11915; -.
DR   PATRIC; fig|354243.3.peg.1026; -.
DR   OrthoDB; 5171781at2; -.
DR   Proteomes; UP000092668; Unassembled WGS sequence.
DR   Proteomes; UP000192713; Unassembled WGS sequence.
DR   Proteomes; UP000466523; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF13531; SBP_bac_11; 1.
DR   SMART; SM00327; VWA; 1.
DR   SUPFAM; SSF53300; vWA-like; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        128..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          502..689
FT                   /note="VWFA"
FT                   /evidence="ECO:0000259|PROSITE:PS50234"
FT   REGION          1..122
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        71..85
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        99..122
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   691 AA;  72122 MW;  E763B964C97E07B7 CRC64;
     MGRHSLPGPD DFAEDPLGRD EPDYGDDDTA TPDPFGFGDP DDDEYVDDYH DALYDDSFGG
     GAGYDADPAQ YMRRGGHDDE ETRYRTGPFG AFGAHAGESP SAERDEPRGG HRNLDRWRRH
     RNDAGPRGVS VGVVAALVTV IVVVGAVILW RFFGNSLSHR SAVAAGACAE GDLTVAVVAD
     PSIADHVQGF ADRFNKTAKP VGDRCVSVQV KPVDSDAVVS GFIGDWPAQL GQRPALWIPG
     SSISAARLQA SAGQETVSDS RSLVTSPVLL AVRPELKPAL QKQTWASLPE LQTDPDGLGR
     LGLPGWGQLR LALPIGGNGD AAFLAGEAVA AGTAPKGAPA TDGTPAVHRL AGAQPQLADS
     SLAEAMNVLL RQGDPAAAPV HAVVTTEQQL FTRAQSLSDP SRSLGSWLPA GPVPVADYPT
     VLLAGSWLSQ EQVSAASEFA RFARKPDQLA ELAKAGFRVE GVASPSSEVT DFPAVSDTLS
     VGDDAMRATL ANALTTLPGS SAVTIMLDAS MTTDEGGKTR LAHVIAALDQ RIRALPPNSA
     VGLWTFDGVE GRNVVTAGPL DEQVNGGLRS ETLVGELDGL SSTSGGAVSF TTLRLVYNQA
     LSNYRAGQTN SVLVITAGPH TDRTLDGPGL QEFIRSNTDP ERPVAVNVID FGADADQATW
     QSVAQLSGGT YQNLRGANTP ELAGALNTLL G
//