ID A0A1B8TWC9_9FLAO Unreviewed; 546 AA.
AC A0A1B8TWC9;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Mechanosensitive ion channel protein MscS {ECO:0000313|EMBL:OBY63799.1};
GN ORFNames=LPB301_13475 {ECO:0000313|EMBL:OBY63799.1};
OS Polaribacter reichenbachii.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae.
OX NCBI_TaxID=996801 {ECO:0000313|EMBL:OBY63799.1, ECO:0000313|Proteomes:UP000092612};
RN [1] {ECO:0000313|Proteomes:UP000092612}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KCTC 23969 {ECO:0000313|Proteomes:UP000092612};
RA Shin S.-K., Yi H.;
RT "Paenibacillus sp. LPB0068, isolated from Crassostrea gigas.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the MscS (TC 1.A.23) family.
CC {ECO:0000256|ARBA:ARBA00008017}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBY63799.1}.
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DR EMBL; LSFL01000035; OBY63799.1; -; Genomic_DNA.
DR RefSeq; WP_068362921.1; NZ_VRMM01000052.1.
DR AlphaFoldDB; A0A1B8TWC9; -.
DR STRING; 996801.BW723_02225; -.
DR KEGG; prn:BW723_02225; -.
DR OrthoDB; 9809206at2; -.
DR Proteomes; UP000092612; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.10.287.1260; -; 1.
DR Gene3D; 2.30.30.60; -; 1.
DR Gene3D; 3.30.70.100; -; 1.
DR InterPro; IPR010920; LSM_dom_sf.
DR InterPro; IPR049278; MS_channel_C.
DR InterPro; IPR023408; MscS_beta-dom_sf.
DR InterPro; IPR006685; MscS_channel_2nd.
DR InterPro; IPR011066; MscS_channel_C_sf.
DR InterPro; IPR011014; MscS_channel_TM-2.
DR InterPro; IPR045042; YnaI-like.
DR PANTHER; PTHR43634:SF2; MECHANOSENSITIVE ION CHANNEL PROTEIN 2, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43634; OW CONDUCTANCE MECHANOSENSITIVE CHANNEL; 1.
DR Pfam; PF00924; MS_channel_2nd; 1.
DR Pfam; PF21082; MS_channel_3rd; 1.
DR SUPFAM; SSF82689; Mechanosensitive channel protein MscS (YggB), C-terminal domain; 1.
DR SUPFAM; SSF82861; Mechanosensitive channel protein MscS (YggB), transmembrane region; 1.
DR SUPFAM; SSF50182; Sm-like ribonucleoproteins; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092612};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..546
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5008615664"
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 243..264
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 334..398
FT /note="Mechanosensitive ion channel MscS"
FT /evidence="ECO:0000259|Pfam:PF00924"
FT DOMAIN 409..494
FT /note="Mechanosensitive ion channel MscS C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21082"
SQ SEQUENCE 546 AA; 62282 MW; 7C0A1288EF868344 CRC64;
MKKLLVLIYF LSFLVNAQEI VKVDLSSPKS TVYTHIYFLQ NDSYEPKKAA KTILGLPEKK
AIEKAIKIKK VLDGKGLFID FNRLPTNANY KDTLDYNSKE RYVLFPQRMP SIYVEKVENS
WYYSSETVAS IDRIYKEVFP WYVNKFQDFI PNSGYTKVLG VELWQFAAVI IMFILAILIF
IIFKKITYTI LQKLQHYITK SNSSLAINTV LKKLAHPISL LVAVKFIDNI FPSLQFSLTV
NKWVFLAINI AETVFWIYVF LKLVKVIMKI YEEFTSKTDN RLDDQLVPIL NNLLTGVVLI
FGFFKVLQLF GVDTTTILAG ATIGGLAFAL ASQDTVKNFI GTVAIFLDKP FHIDDWISAG
EVTGTVEEVG FRSTRVRAAD TTVYQIPNSK LAEMVINNSG LRLYRRYNTN LGLRYDTPPE
LIEAFVNGVR IIIKEHPETK SDSYNVEFTG FGDSALLVMM NVYFKSLAWG TEQSSKHRLH
MAILKLAAEL GVEFAFPSTT VTIEQFPDKS NLSPKYNTDK EKIKKSLDKV LENFRNDTPP
ENTPES
//
