ID   A0A1B8TXJ5_9FLAO        Unreviewed;       984 AA.
AC   A0A1B8TXJ5;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE            EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
GN   ORFNames=LPB3_07500 {ECO:0000313|EMBL:OBY64229.1};
OS   Polaribacter vadi.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae.
OX   NCBI_TaxID=1774273 {ECO:0000313|EMBL:OBY64229.1, ECO:0000313|Proteomes:UP000092584};
RN   [1] {ECO:0000313|Proteomes:UP000092584}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LPB0003 {ECO:0000313|Proteomes:UP000092584};
RA   Shin S.-K., Yi H., Kim E.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC         diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC         Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC         ChEBI:CHEBI:173112; EC=2.7.7.7;
CC         Evidence={ECO:0000256|ARBA:ARBA00024632};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OBY64229.1}.
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DR   EMBL; LSFM01000022; OBY64229.1; -; Genomic_DNA.
DR   RefSeq; WP_065318979.1; NZ_LSFM01000022.1.
DR   AlphaFoldDB; A0A1B8TXJ5; -.
DR   STRING; 1774273.LPB03_04995; -.
DR   KEGG; pob:LPB03_04995; -.
DR   OrthoDB; 9803237at2; -.
DR   Proteomes; UP000092584; Unassembled WGS sequence.
DR   GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd07431; PHP_PolIIIA; 1.
DR   Gene3D; 1.10.150.870; -; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 2.
DR   InterPro; IPR011708; DNA_pol3_alpha_NTPase_dom.
DR   InterPro; IPR040982; DNA_pol3_finger.
DR   InterPro; IPR004805; DnaE2/DnaE/PolC.
DR   InterPro; IPR029460; DNAPol_HHH.
DR   InterPro; IPR004013; PHP_dom.
DR   InterPro; IPR003141; Pol/His_phosphatase_N.
DR   InterPro; IPR016195; Pol/histidinol_Pase-like.
DR   NCBIfam; TIGR00594; polc; 1.
DR   PANTHER; PTHR32294; DNA POLYMERASE III SUBUNIT ALPHA; 1.
DR   Pfam; PF07733; DNA_pol3_alpha; 1.
DR   Pfam; PF17657; DNA_pol3_finger; 1.
DR   Pfam; PF14579; HHH_6; 1.
DR   Pfam; PF02811; PHP; 1.
DR   SMART; SM00481; POLIIIAc; 1.
DR   SUPFAM; SSF89550; PHP domain-like; 1.
PE   4: Predicted;
KW   DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW   DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          1..68
FT                   /note="Polymerase/histidinol phosphatase N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00481"
SQ   SEQUENCE   984 AA;  113040 MW;  7E49262BED5E84EC CRC64;
     MYLNCHTYYS LRYGTFSETE LLQLALENNV HTLALTDINN TSACMNFVQQ AKKANIKPVV
     GVDFRNGNTQ QFVALAKTNL GFQNINRFLS SFLESKTSIP EQPPFLEEVI IIYPFEKVLE
     LNITNFKENE FIGISLAEVN KLRFSYLNEF TDKIVIQQQV TIRNKKDFNA HRILRAIDKN
     TLLSKLEASE QCLETDKMYQ VDDLQNHFKD FPNAIKNTQV ILNQCNINFG FGKERTNQNL
     QRYNNSFEED CKQLNQLCQS KIAKRYKEIT EEVNNRLQKE LKVIIDLKFV SFFLINYDII
     QHANSNNFFH VGRGSGANSI VAYILGITDV DPIELDLYFE RFINPFRASP PDFDIDFSWK
     DRDIMTQYIF DRFKNVALLA TYVTFKYKAV VRELGKVFGL PKEEIDKLSK GIVVGQLDEM
     ANLVLKYGKL IEGFPNYVSV HAAGVLILDK PIHYYSATNL PPKNFPTVQF DMNIADDVGI
     FKFDILGQRG LAKIKDALEI IKENNPDAPK IDITDVATFK KDKNINNLLK TGGAIGAYYV
     ESPAMRGLMQ KLQTQDYLGL VAASSIIRPG VSSSGMKEEF IKRHRFPEKR KEANPILLKI
     MPETYGVMVY QEDVMKVANQ FADLKLGEAD VLRRGMSGKY RSLKEFKAVE EKFIANCRKK
     GHKDELIFKV WDQIKSFAGY AFAKGHSASY AVESYQSLFL KCYYPIEFMV AVLNNGGGFY
     TAEHYIHEAK MCGAKIELPC INQSDHANRV KGKTIFLGFG YLKSLEQLTI QRILNERQLV
     GTFSSLDDFL ERVRISIEQL SILIRMDAFR FTNKAKTTLL WEATFKLNVS KNRKNQQAAL
     FRIQQKKFQI PELQSNWVEN FYDEIELLGF TIQNYFSLVI DEFHPHIKAK EMAQFPDQNV
     LLYGQLVTTR FNQTSQGKLM RLSTFIDAEG NYFDAVHFTN VVHQYPINGM GVYACYGKIT
     NRFGFCSMNI IQSKKMSIAT DPRS
//