ID A0A1B8W0D0_9BACI Unreviewed; 1071 AA.
AC A0A1B8W0D0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Membrane transport protein MMPL domain-containing protein {ECO:0000259|Pfam:PF03176};
GN ORFNames=A7975_22260 {ECO:0000313|EMBL:OBZ10091.1};
OS Bacillus sp. FJAT-26390.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1743142 {ECO:0000313|EMBL:OBZ10091.1, ECO:0000313|Proteomes:UP000092623};
RN [1] {ECO:0000313|EMBL:OBZ10091.1, ECO:0000313|Proteomes:UP000092623}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FJAT-26390 {ECO:0000313|EMBL:OBZ10091.1,
RC ECO:0000313|Proteomes:UP000092623};
RA Liu X., Pan Z., Shi H., Ge C., Che J., Lan J., Chen Z., Chen Q., Liu B.,
RA Zhu Y., Wang J., Liu G.;
RT "Bacillus sp. FJAT-26390.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBZ10091.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; MAQX01000033; OBZ10091.1; -; Genomic_DNA.
DR RefSeq; WP_065387010.1; NZ_MAQX01000033.1.
DR AlphaFoldDB; A0A1B8W0D0; -.
DR Proteomes; UP000092623; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.10.287.950; Methyl-accepting chemotaxis protein; 2.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR011049; Serralysin-like_metalloprot_C.
DR InterPro; IPR023908; xxxLxxG_rpt.
DR NCBIfam; TIGR03057; xxxLxxG_by_4; 1.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF101967; Adhesin YadA, collagen-binding domain; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092623};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 183..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..337
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 369..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 875..894
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 901..927
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 933..955
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 976..996
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1002..1026
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 63..369
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT DOMAIN 718..1044
FT /note="Membrane transport protein MMPL"
FT /evidence="ECO:0000259|Pfam:PF03176"
FT REGION 1049..1071
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1071 AA; 113977 MW; 6F581AD370053C3D CRC64;
MRTVLKFRWV VLALWLVAAV GLMLSAPGME ELVRTKGQIN VPDGYSSTMA NELEKAIGEK
DGASSSSGMA TVLVFHKEGG LSDTDLAEVK SGINKLKSEG EGIGVLSVTT HFDTKELEEQ
MVSKDGSTVL ALVNVEAGDR ELVELRDGLY EAISDVKVEH YYTGNWIISE DVVQSSQEGL
KKTEFITLGF ILIILFVVFR SAIAPLVPLV AVGFTYLISQ SIIAYLVEYF DFPLSNFTQI
FLVAVLFGIG TDYCILLISR FKEELTHSGG DKTEAIIQTY RTAGRTVLFS GLAVLVGFAA
IGFSTFMLYR SAVAVAVGVA VLLIALFTIV PFFMAVLGTK LFWPAKGSLE HKPSKLWGTV
GKFSLKRPLW ALIILAVIIV PFLTAYKGTI SFNSLDEIGD KYDSVKAFNM ISDSFGPGDS
LPTTVIVKAD KPMDTPEGLA TLEQVSRELA NTGGVKAVRS ATRPTGDVME QFLVSDQVVT
LEDGLGQSGE GLGKIGDGLT EASTALSKNA PKLNEAVDGA GQLVDGTNEL KAGIVQLGTG
LKQIQQGLKD GSVGAGELSE GLKQAQSSAE QLAGASRKLL GSYEQLGGGL GQLTGAYSAI
ASEQAKLADG LSGVEQGLTG LQESYPELQN DEKFKQALST LGQLQQGAAG ISGQLSQLNE
QLSGLSSGMT QANAGFLQAS EGQSALASGL GKLAAGLGEL QKGISQAAAG QGQIISKLPS
VTQGFNELSD GQKELQAGFA SLNDQLGELT NGLDQSVDGL SQVTEGLNSA GGYLNGLAGS
PNKQMTGWYI PEEAIANKEF QAALDVYMSE DRQTAKFDVV FSGNPYAQET MAEIDGLEAA
VNRAIQGTDY SGAQVAIGGV TSMNHDLSNI SKADYSRTVI LMLIGISIIL IILFRSIVMP
LYMIASLLVT FYSSMAIAEV IFVRLLGQSG ISWAVPFFGF VMLVALGIDY SIFLMDRFKE
YRHLSPMEAI LEAMKNMGTV IMSAAVILGG TFAAMLPSGV MSLLQIATIV LCGLFMYALL
MLPLFIPVMV RTFGPANWWP FMARKQAGEQ GNRVHDGQSL KGHRVSPDST H
//
