ID A0A1B8WKS4_9BACI Unreviewed; 579 AA.
AC A0A1B8WKS4;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Two-component sensor histidine kinase {ECO:0000313|EMBL:OBZ17211.1};
GN ORFNames=A7975_04830 {ECO:0000313|EMBL:OBZ17211.1};
OS Bacillus sp. FJAT-26390.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=1743142 {ECO:0000313|EMBL:OBZ17211.1, ECO:0000313|Proteomes:UP000092623};
RN [1] {ECO:0000313|EMBL:OBZ17211.1, ECO:0000313|Proteomes:UP000092623}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FJAT-26390 {ECO:0000313|EMBL:OBZ17211.1,
RC ECO:0000313|Proteomes:UP000092623};
RA Liu X., Pan Z., Shi H., Ge C., Che J., Lan J., Chen Z., Chen Q., Liu B.,
RA Zhu Y., Wang J., Liu G.;
RT "Bacillus sp. FJAT-26390.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OBZ17211.1}.
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DR EMBL; MAQX01000001; OBZ17211.1; -; Genomic_DNA.
DR RefSeq; WP_065384327.1; NZ_MAQX01000001.1.
DR AlphaFoldDB; A0A1B8WKS4; -.
DR Proteomes; UP000092623; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd06225; HAMP; 1.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR010559; Sig_transdc_His_kin_internal.
DR PANTHER; PTHR34220; SENSOR HISTIDINE KINASE YPDA; 1.
DR PANTHER; PTHR34220:SF7; SENSOR HISTIDINE KINASE YPDA; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF06580; His_kinase; 1.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF158472; HAMP domain-like; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:OBZ17211.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000092623};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 306..358
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
SQ SEQUENCE 579 AA; 66167 MW; 34A739F094670AFD CRC64;
MRRRISLPLK LFFIVFAFVL SCIILISQLS YRYVQKEIRT TDIYYTNQIL DKVDQYFTVN
FSSFQTILFS VETSVKANID NTEVIKKQLR ELYELNSNYV SNIYLIKSDL SILGGSTPTR
IFDEPLSERE PLFDAADKNR RTTFVSDPYK SKYSGWTVTM VRYLNDAPYP MAIAVDLDLN
AIEETLFKIN KKEQMNLALI TASGKIIAGF SENKGPLNIQ DHTFSIGETS AEQILNTTET
SLQLHTKDGI PVSLLKKPTE KFNWTIISIN DESRLKAALS RLETYYIELL AAGLLLSLFI
SFFIAKYIRN PLYALKTKMK RVEQGFLTTT ITINRNDEFG DLSRAFDRML QQIVELIRRA
ELHNELERKL EIQVLQSQIN PHFLYNTLGS ISNVIRLGQI EKVDVVIGSL ISLLEYGIDD
ASEKVSLHQE LRNVSDYIEI QNIRYNRNFQ LIENIEAGLI DFPVFRMLLQ PLVENSIFHG
YNGGGIEGPI TIHAYREGGI VIIEVVDQGE GIPADKIKHI LFSEPSNVEV KRKRIGLNNI
HGRIRLHYGE QFGLQIISIP KEITRVRAFF PAGLLKGDA
//
