ID A0A1B8Y387_XENTR Unreviewed; 661 AA.
AC A0A1B8Y387;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=CUB domain-containing protein {ECO:0000259|PROSITE:PS01180};
DE Flags: Fragment;
GN ORFNames=XENTR_v900271992mg {ECO:0000313|EMBL:OCA17400.1};
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364 {ECO:0000313|EMBL:OCA17400.1};
RN [1] {ECO:0000313|EMBL:OCA17400.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Nigerian {ECO:0000313|EMBL:OCA17400.1};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Ottilar R., Schmutz J., Salamov A., Cheng J.F., Lucas S., Pitluck S.,
RA Gundlach H., Guo Y., Haberer G., Nasrallah J., Mayer K.F.X.,
RA van de Peer Y., Weigel D., Grigoriev I.V.;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OCA17400.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nigerian {ECO:0000313|EMBL:OCA17400.1};
RX PubMed=20431018; DOI=10.1126/science.1183670;
RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J.,
RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., Blitz I.L.,
RA Blumberg B., Dichmann D.S., Dubchak I., Amaya E., Detter J.C., Fletcher R.,
RA Gerhard D.S., Goodstein D., Graves T., Grigoriev I.V., Grimwood J.,
RA Kawashima T., Lindquist E., Lucas S.M., Mead P.E., Mitros T., Ogino H.,
RA Ohta Y., Poliakov A.V., Pollet N., Robert J., Salamov A., Sater A.K.,
RA Schmutz J., Terry A., Vize P.D., Warren W.C., Wells D., Wills A.,
RA Wilson R.K., Zimmerman L.B., Zorn A.M., Grainger R., Grammer T.,
RA Khokha M.K., Richardson P.M., Rokhsar D.S.;
RT "The genome of the Western clawed frog Xenopus tropicalis.";
RL Science 328:633-636(2010).
RN [3] {ECO:0000313|EMBL:OCA17400.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=Nigerian {ECO:0000313|EMBL:OCA17400.1};
RA Sessions A., Jenkins J., Mitros T., Lyons J.T., Dichmann D.S., Robert J.,
RA Harland R.M., Rokhsar D.S.;
RT "WGS assembly of Xenopus tropicalis.";
RL Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR EMBL; KV460501; OCA17400.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B8Y387; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00041; CUB; 1.
DR CDD; cd00054; EGF_CA; 2.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 2.60.120.290; Spermadhesin, CUB domain; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 3.
DR InterPro; IPR000859; CUB_dom.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR035914; Sperma_CUB_dom_sf.
DR InterPro; IPR011641; Tyr-kin_ephrin_A/B_rcpt-like.
DR PANTHER; PTHR24046; SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR24046:SF4; SIGNAL PEPTIDE, CUB AND EGF-LIKE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00431; CUB; 1.
DR Pfam; PF07645; EGF_CA; 2.
DR Pfam; PF07699; Ephrin_rec_like; 3.
DR SMART; SM00042; CUB; 1.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM01411; Ephrin_rec_like; 3.
DR SUPFAM; SSF57184; Growth factor receptor domain; 3.
DR SUPFAM; SSF49854; Spermadhesin, CUB domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS01180; CUB; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS01187; EGF_CA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 472..584
FT /note="CUB"
FT /evidence="ECO:0000259|PROSITE:PS01180"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OCA17400.1"
SQ SEQUENCE 661 AA; 73738 MW; C5427FCD00752379 CRC64;
VDECSFERTC DHICINYPGS YECLCHKGYT LYGMTHCGDI NECSINNGSC DYGCVNTPGS
YECVCPPGKR LHWNKKDCIE MVKCLPNSKP PPRAQLICSK AGGIDSCFLS CPSNTLFVPD
SESSYTLSCG VPVQQGKSVQ KRNATVPSSC GDSLGPPITQ KARFKIKDAK CHLRPRSKEK
IRESGRQSPT DNCHVTFVNL KCDSSKKKRR GRNSPAKEVS HITAEFELEI KREEVTDSCN
SDCVRRRMEQ KLQTAIKTLR KSINKQQFYI QFSGAEYEVA QKPAKVSEVQ EPCSAGQILL
DGKCVFCPAG TFYNGEHNQC IPCSPGTYQD TRGQLTCEPC PSNDGSGIGG ARNVSECGGQ
CAPGYFSLDG FKPCRSCPLG TYQPESGRTL CFPCGGGLVT KYESAVSFQD CETKVHCSPG
HYYNSTTHRC IRCPIGTYQP EFGLNFCITC PGNTSTDFDG STNVTHCKNQ HCGGELGDYT
GYIESPNYPG DYPAHVECIW NINPPPKRRI LIVVPEIFLP IEDECGDVLV MRKSASPASI
TTYETCQTYE RPIAFTSRSR KLWIQFKSNE GNSGKGFQVP YVTYDEDYQQ LIEDIVRDGR
LYASDNHQEI LKDKKLIKAL FSVLAHPQNY FKYAEESKKM FPMSFIKLLR SKVSRFLRPY
K
//
