ID A0A1B9CSS6_MYCMA Unreviewed; 1389 AA.
AC A0A1B9CSS6;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Type VII secretion protein EccC {ECO:0000313|EMBL:OCB45543.1};
GN ORFNames=A5677_05255 {ECO:0000313|EMBL:OCB45543.1};
OS Mycobacterium malmoense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1780 {ECO:0000313|EMBL:OCB45543.1, ECO:0000313|Proteomes:UP000092683};
RN [1] {ECO:0000313|EMBL:OCB45543.1, ECO:0000313|Proteomes:UP000092683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E3012 {ECO:0000313|EMBL:OCB45543.1,
RC ECO:0000313|Proteomes:UP000092683};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCB45543.1}.
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DR EMBL; MBEE01000232; OCB45543.1; -; Genomic_DNA.
DR RefSeq; WP_065483547.1; NZ_MBEE01000232.1.
DR OrthoDB; 9807790at2; -.
DR Proteomes; UP000092683; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR023836; EccCa-like_Actinobacteria.
DR InterPro; IPR023837; EccCb-like_Actinobacteria.
DR InterPro; IPR002543; FtsK_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR03924; T7SS_EccC_a; 1.
DR NCBIfam; TIGR03925; T7SS_EccC_b; 1.
DR PANTHER; PTHR22683; SPORULATION PROTEIN RELATED; 1.
DR PANTHER; PTHR22683:SF1; TYPE VII SECRETION SYSTEM PROTEIN ESSC; 1.
DR Pfam; PF01580; FtsK_SpoIIIE; 2.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50901; FTSK; 3.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Membrane {ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00289}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 476..678
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 856..1050
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT DOMAIN 1159..1352
FT /note="FtsK"
FT /evidence="ECO:0000259|PROSITE:PS50901"
FT BINDING 499..506
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 874..881
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
FT BINDING 1176..1183
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00289"
SQ SEQUENCE 1389 AA; 152538 MW; F3C612E230438A1E CRC64;
MKRGFARPTP EKPPVIKPEN IVLPTPLSIP PPEGKPWWLV VVGVLVVGLL IGMVGMTFAS
GSHVFGGAGA IFPIFMIGGV AMMMFGGRFG GQQQMSRPKL DSMRAQFMLM LDMLRETAHE
SADSMDANYR WFHPAPTTLS AAVGSPRMWE RKPDGKDLNF GVVRVGVGMT RPEVTWGEPQ
NMPTDIELEP VTGKALQEFG RYQSVVYNLP KMISLLVEPW YSLDGEREQV LGLMRAIICQ
LAFSHGPDHV QMVVVSSDLD EWDWVKWIPH FGDPRRQDAA GNARMVYSSV REFAAEQAEL
FAGRGSFTPR HASSSAQTPT PHTVIVADVV DPQWEYVISA EGVDGVTFFD LTGSSMWTSV
PERTLRFDDK GVIEALPRDR DTWMVIDEKP WFFALTDHIS IAEAEEFAQA LARWRLAEAY
EEIGQRVAHI GARDIMAYYG IDDPGRIDFQ ALWGARTDTM GRSRLRAPFG NRSDNGELLF
LDMKSLDEGG DGPHGVMSGT TGSGKSTLVR TVIESLMLSH PPEELQFVLA DLKGGSAVKP
FAGVPHVSRI ITDLEEDQAL MERFLDALWG EIARRKAICD SAGVDDAKEY NSVRLRMQAR
GQDMAPLPML VVVIDEFYEW FRIMPTAVDV LDSIGRQGRA YWIHLMMASQ TIESRAEKLM
ENMGYRLVLK ARTAGAAQAA GVPNAVNLPA QAGLGYFRRS LEDIVRFQAE FLWRDYFPRG
LTDDGEEAPT LVHSIDYVRP QLFTNSFTPL EVSVGGPELT PAALTNGETL EADGAPTEDD
DVEGIRVPKV GTVIIDQLRK IDFEPYRLWQ PPLNQPVAID ELVDRFLGHP WQEDYGTARD
LVFPIGIIDR PFKHDQPPWT VDTSGPGANV LILGAGGSGK TTALQTLICS AALTHTPEQV
QFYCLAYSST ALTTVARLPH VGEVAGPTDP YGVRRTVAEL LALVRQRKST FLEYGIASME
VFRRRKFGGE PGPVPNDGFG DVYLVVDNYR ALAEENEVLI EQVNLIINQG PSFGVHVVVT
ADRESELRPP VRSGFGSRVE LRLAAVEDAK LVRSRFAKDV PVKPGRGMVA VNYVRLDSDP
QAGLHTLVAR PALGTTPDYV FESDSIIDAV SRLTSSQAPP VRRLPARFDL EQLREVAARD
TRQGVGAGGI AWAISELDLS PVYLNFAENA HLMVTGRREC GRTTTLATIM SEIGRLYAPG
ASSAPTPPAG QPSAQVWLVD PRRQLLTTLG SEYVEKFAYN LDGVQAMMGE LAAVLAGREP
PPGLSAEELL SRSWWSGPEI FLIVDDIQQL PAGFDSPLHK AAPWVTRAAD VGLHVIVTRT
FGGWSSAGSD PMLRALAQAN APLLVMDADP DEGFIRGKMK GGPLPRGRGL LMAEDTGVFV
QVAATELRK
//
