ID A0A1B9DAN2_MYCMA Unreviewed; 549 AA.
AC A0A1B9DAN2;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=A5677_01930 {ECO:0000313|EMBL:OCB57849.1};
OS Mycobacterium malmoense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1780 {ECO:0000313|EMBL:OCB57849.1, ECO:0000313|Proteomes:UP000092683};
RN [1] {ECO:0000313|EMBL:OCB57849.1, ECO:0000313|Proteomes:UP000092683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E3012 {ECO:0000313|EMBL:OCB57849.1,
RC ECO:0000313|Proteomes:UP000092683};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC {ECO:0000256|ARBA:ARBA00006637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCB57849.1}.
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DR EMBL; MBEE01000079; OCB57849.1; -; Genomic_DNA.
DR RefSeq; WP_065446207.1; NZ_MBEE01000079.1.
DR AlphaFoldDB; A0A1B9DAN2; -.
DR OrthoDB; 3713880at2; -.
DR Proteomes; UP000092683; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
DR Pfam; PF04851; ResIII; 1.
DR PRINTS; PR00851; XRODRMPGMNTB.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:OCB57849.1};
KW Helicase {ECO:0000313|EMBL:OCB57849.1};
KW Hydrolase {ECO:0000313|EMBL:OCB57849.1};
KW Nucleotide-binding {ECO:0000313|EMBL:OCB57849.1}.
FT DOMAIN 190..344
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 395..545
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
SQ SEQUENCE 549 AA; 60597 MW; B46B4E0B59753283 CRC64;
MTDGPLIVQS DKTVLLEVDH EQAGAARAAI APFAELERAP EHVHTYRITP LALWNARAAG
HDAEQVVDAL VSFSRYAVPQ PLLVDIVDTM ARYGRLQLVK HPAHGLTLVS LDRAVLEEVL
RNKKIAPMLG ARIDDDTVVV HPSERGRVKQ MLLKIGWPAE DLAGYVDGEA HPISLAQDGW
HLRDYQQMAT DSFWSGGSGV VVLPCGAGKT LVGAAAMAKA SATTLILVTN VVAARQWKRE
LVARTSLTED EVGEYSGERK EIRPVTISTY QMVTRRTKGE YRHLELFDSR DWGLIIYDEV
HLLPAPVFRM TADLQSKRRL GLTATLVRED GREGDVFSLI GPKRYDAPWK DIEAQGWIAP
AECVEVRVTM TDNERMMYAT AEPEERYKLC STAHSKIAVV KSVLGRHPGE QTLVIGAYLD
QLDELGAELN APVIQGSTRT KEREELFDAF RRGEVTTLVV SKVANFSIDL PEASVAVQVS
GTFGSRQEEA QRLGRLLRPK ADGGGAIFYS VVARDSLDAE YAAHRQRFLA EQGYGYIIRD
ADDLLGPAI
//
