ID A0A1B9DBJ5_MYCMA Unreviewed; 452 AA.
AC A0A1B9DBJ5;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=GABA permease {ECO:0000313|EMBL:OCB58986.1};
GN ORFNames=A5677_15750 {ECO:0000313|EMBL:OCB58986.1};
OS Mycobacterium malmoense.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium.
OX NCBI_TaxID=1780 {ECO:0000313|EMBL:OCB58986.1, ECO:0000313|Proteomes:UP000092683};
RN [1] {ECO:0000313|EMBL:OCB58986.1, ECO:0000313|Proteomes:UP000092683}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=E3012 {ECO:0000313|EMBL:OCB58986.1,
RC ECO:0000313|Proteomes:UP000092683};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family.
CC {ECO:0000256|ARBA:ARBA00008583}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCB58986.1}.
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DR EMBL; MBEE01000064; OCB58986.1; -; Genomic_DNA.
DR RefSeq; WP_065472027.1; NZ_MBEE01000064.1.
DR AlphaFoldDB; A0A1B9DBJ5; -.
DR OrthoDB; 5297508at2; -.
DR Proteomes; UP000092683; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006865; P:amino acid transport; IEA:InterPro.
DR GO; GO:0055085; P:transmembrane transport; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR004840; Amoino_acid_permease_CS.
DR PANTHER; PTHR43495; GABA PERMEASE; 1.
DR PANTHER; PTHR43495:SF5; GAMMA-AMINOBUTYRIC ACID PERMEASE; 1.
DR Pfam; PF00324; AA_permease; 1.
DR PIRSF; PIRSF006060; AA_transporter; 1.
DR PROSITE; PS00218; AMINO_ACID_PERMEASE_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 16..37
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 43..62
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 122..142
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 149..174
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 330..348
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..438
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
SQ SEQUENCE 452 AA; 48021 MW; CB13186C36F52E71 CRC64;
MASTKQLRQG LSQRQLSMIA LGGVIGAGLF VGSGVVIKDT GPAAFLSYAL CGLLIVLVMR
MLGEMAAADP STGSFADYAA KALGGWAGFS VAWLYWYFWV IVVGFEAVAG GKVLGYWFHA
PLWLLSLCLM LLMTATNLFS VTSFGEFEFW FAGIKVATIA IFLGVGAAFV LGLVPGRPGG
LANLTAHGGF FPKGVGAVFA AIVVVIFSMV GAEIVTVAAA ESRDPHLAVQ KATRSVVTRI
GVFFVGSIFL LVVILPWDSV ELGASPYVAA LHHLGLRGAD QVMNAVVLTA VLSCLNSGLY
TASRMLFVLA ERGEAPMRLV SLSGRGVPHI AILCSSAVGF GCVVMARVAP DTVFLFLLNS
SGAIILFVYW LIALSQIILR RRTPAENLRV KMWFFPVLSI LTLAAITAVL VQMAFDRSAR
SQLWLSLLSW AVVIGLYLAA RARGRLPARP GA
//
