ID A0A1B9EKZ3_9ACTN Unreviewed; 483 AA.
AC A0A1B9EKZ3;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Guanine/hypoxanthine permease PbuG {ECO:0000313|EMBL:OCC08402.1};
GN Name=pbuG_2 {ECO:0000313|EMBL:OCC08402.1};
GN ORFNames=A3Q37_05800 {ECO:0000313|EMBL:OCC08402.1};
OS Streptomyces sp. PTY087I2.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1819298 {ECO:0000313|EMBL:OCC08402.1, ECO:0000313|Proteomes:UP000093256};
RN [1] {ECO:0000313|EMBL:OCC08402.1, ECO:0000313|Proteomes:UP000093256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PTY087I2 {ECO:0000313|EMBL:OCC08402.1,
RC ECO:0000313|Proteomes:UP000093256};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCC08402.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LZRD01000029; OCC08402.1; -; Genomic_DNA.
DR RefSeq; WP_065488738.1; NZ_LZRD01000029.1.
DR AlphaFoldDB; A0A1B9EKZ3; -.
DR PATRIC; fig|1819298.4.peg.6020; -.
DR Proteomes; UP000093256; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000093256};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 41..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 73..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..118
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..143
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 155..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..217
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 224..243
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 370..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..444
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 483 AA; 50584 MW; F48AF6C468B10AA3 CRC64;
MHASPTSPPP PDAKPAASGG AVDRFFRISE RGSSYIREIR GGFATFFTMA YILVLNPIIL
GGAEDKFGEQ LDSVQLVTAT ALVAAVMTLI MGVGGNLPLA LAAGLGINAV VAFQIAPLMS
WEDAMGLIVL EGLLICVLVM TGLREAIMHA IPQPLKQAIS VGIGLFIAFI GFVDAGFVTR
IPDAANSTVP VQLGTGTLTG WPMLVFCLGV LLTIVLVTRK VKGAILISIV LMTAIAIVIN
EIADIKAWGL TSPSIPGNPV AAPDFGLLWH FDLLGSFGQV SVLTVVLLIF TLILSDFFDT
MGTVVGVTAE AGLLDERGQV PGLGRVLLID GAAAVVGGAT SSSSATTYIE SAAGVGEGAR
TGFANLITGG LFALALFLTP VLTIVPMQAA APALVVVGFL MMTQVKHIDW DRYDVAIPAF
LTIVVMPFTY SITNGIGAGF VAYVIIKSCL GKAREVHWLL WGTAVLFLIY FLIDPLEQVL
GMK
//
