ID A0A1B9EU72_9ACTN Unreviewed; 722 AA.
AC A0A1B9EU72;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Serine/threonine-protein kinase PknB {ECO:0000313|EMBL:OCC11051.1};
DE EC=2.7.11.1 {ECO:0000313|EMBL:OCC11051.1};
GN Name=pknB_5 {ECO:0000313|EMBL:OCC11051.1};
GN ORFNames=A3Q37_03169 {ECO:0000313|EMBL:OCC11051.1};
OS Streptomyces sp. PTY087I2.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1819298 {ECO:0000313|EMBL:OCC11051.1, ECO:0000313|Proteomes:UP000093256};
RN [1] {ECO:0000313|EMBL:OCC11051.1, ECO:0000313|Proteomes:UP000093256}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PTY087I2 {ECO:0000313|EMBL:OCC11051.1,
RC ECO:0000313|Proteomes:UP000093256};
RA Kjaerup R.B., Dalgaard T.S., Juul-Madsen H.R.;
RL Submitted (JUN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OCC11051.1}.
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DR EMBL; LZRD01000012; OCC11051.1; -; Genomic_DNA.
DR RefSeq; WP_065484609.1; NZ_LZRD01000012.1.
DR AlphaFoldDB; A0A1B9EU72; -.
DR PATRIC; fig|1819298.4.peg.3301; -.
DR Proteomes; UP000093256; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR46082:SF12; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR46082; ATP/GTP-BINDING PROTEIN-RELATED; 1.
DR Pfam; PF00069; Pkinase; 1.
DR Pfam; PF13374; TPR_10; 3.
DR Pfam; PF13424; TPR_12; 2.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Kinase {ECO:0000313|EMBL:OCC11051.1};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU10141};
KW Reference proteome {ECO:0000313|Proteomes:UP000093256};
KW Transferase {ECO:0000313|EMBL:OCC11051.1}.
FT DOMAIN 11..280
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT BINDING 40
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 722 AA; 79381 MW; 0EC8DB4F2B4CCC2E CRC64;
MADTRLIQSR YRLLELIGRG GMGEVWRALD ESLGRQVAVK CLKPMGPQHD QAFTRILRER
FRREARVAAS LQHRGVTVVH DFGEYEGVLY LVMELLDGQN LSQLLEENQQ HPLPVEHVVD
IAEQVADALG YTHRQGIVHR DLKPANIMRL TDGTVKICDF GIARLGHDIG MTSRLTTTGL
AMGTPHYMSP EQISGKEVDH RSDLYSLGCV LYEIATGVPP FDQEDAWAVL VGHRDTPPEP
LRTHRAELPG FFDRVVLDLL AKAPEERPVD AGDLRRRIVL GRTGEQPALG PGPLAHSGAL
PLPAPRERAL PAWTRSMTAG HRATGPHAEL PDPAAGLTGQ WTTARATVPH TGSFVSVSAG
PPAPDLLARL EGRHSAGIDL GRLGRWEEAG EVHRQVAEQR DRVLGPDHPD TLASHYEIGL
TLSRTGRAEE ALRAFTRVAE GRERTLGPDH PQTLAARQGT AHALGRLGRH AEAHQVYGTV
LAVRERVMGP DHPDTLRCRH NLAFNLCRLG RPEESCRIAR EVADARARVL GPDHPDTLVT
RYEVAYTLGR LGRWAEALAT YQEVARARAD VLGADHPDTF AARYEAGISL GRLGRDEEAL
ELYRSLVADR TRTAGAADPE TLRARHGLGV NLGRLGRWDE ALAEAREVCA LREHALGPDH
PDTVISRREV AAGLGWLGRW SEALVAYRQV AEARTRTLGP DHPQTLAARD DEAHCLERLA
QA
//
