ID A0A1B9FVN3_9TREE Unreviewed; 830 AA.
AC A0A1B9FVN3;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Magnesium transporter NIPA2 {ECO:0008006|Google:ProtNLM};
GN ORFNames=I302_07177 {ECO:0000313|EMBL:OCF22832.1};
OS Kwoniella bestiolae CBS 10118.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296100 {ECO:0000313|EMBL:OCF22832.1, ECO:0000313|Proteomes:UP000092730};
RN [1] {ECO:0000313|EMBL:OCF22832.1, ECO:0000313|Proteomes:UP000092730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10118 {ECO:0000313|EMBL:OCF22832.1,
RC ECO:0000313|Proteomes:UP000092730};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus bestiolae CBS10118.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10118 {ECO:0000313|Proteomes:UP000092730};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KI894024; OCF22832.1; -; Genomic_DNA.
DR RefSeq; XP_019043902.1; XM_019193779.1.
DR AlphaFoldDB; A0A1B9FVN3; -.
DR GeneID; 30211576; -.
DR VEuPathDB; FungiDB:I302_07177; -.
DR OrthoDB; 53219at2759; -.
DR Proteomes; UP000092730; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.3730.20; -; 1.
DR InterPro; IPR008521; Mg_trans_NIPA.
DR PANTHER; PTHR12570:SF98; DUF803 DOMAIN MEMBRANE PROTEIN (AFU_ORTHOLOGUE AFUA_2G07880); 1.
DR PANTHER; PTHR12570; UNCHARACTERIZED; 1.
DR Pfam; PF05653; Mg_trans_NIPA; 1.
DR SUPFAM; SSF103481; Multidrug resistance efflux transporter EmrE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092730};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 32..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 104..125
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 167..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 270..290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 296..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 439..470
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 556..600
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 608..627
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 637..830
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 578..600
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 609..623
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 688..717
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 760..805
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 830 AA; 89095 MW; BDA55A8526CC20C4 CRC64;
MSSSITSSAT SSISASASAA SGLIDKSRNP NFKIVGICLA VGSGLLIGSS FVIKKKGLLN
STKKYGNVAG EGHGYLKSWL WWAGMITMIV GEICNFVAYA FTEAILVTPM GALSVVVAAI
LSHFLLKEKL TFFGWIGCTL CIMGAVILAL NAPEEQSVTT INEFKKLFLS VGFLVWASLL
IAGSLVTIFF VAPRWGKKSM LPYISICSLI GGISVSCTQG LGASIVTSIQ GNNQVKNWFF
WFLFVFVVIT LLTEINYLNK ALELFNTSMV VPVYFCFFSS ATLITSFILY QGLKASAVTL
ITMVLGFLVT CLGITLLQLS KVDPETLDTK LDRKSTILMQ AAKHQTEDAE KGELTSAEDP
GMDALRGGFG AVGSIIRARS VSRRMSTSSS GTGLGGGKGM YGYSTGNLST HGLGHLERFQ
LSDNPMPADA MDQISLHSAK SPSALSPSGG FPHHHNQYFP SPQRSKSQLK ASQNPFEYIP
LDIITSPNIK FNSNSYKVLN SPLRRVSNSI ATLSTLNTSI STSEKAQAND QILFSPLSKQ
FEEADVVHQY HYGSQPDDAA VHSYRPHPPP HSQGSIPPPS PSASASGMPT MGNRQPSSGS
VYPVIEEADE EDISSKEKEK ASSSRVYTNP VIVRDQAYLP NSNSDYLDPY THPQPADLPT
PQKLNPGHRG FSGLFHFPSG PDLSLGSHGR RSKSKDRSEK FPSTKKGEKD ELDKQERTAL
VPSTSYDDEI TYESDDDLDG DGRTTTENAH EAEAQIGVGH RVNLSTSTST TATSDALPAS
SRTTTTFGTN PGDRSRESSS GSGSGPMGPR ALPSKGRKDP PGFAGPRYGL
//
