ID A0A1B9FWC7_9TREE Unreviewed; 811 AA.
AC A0A1B9FWC7;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Protein SDA1 {ECO:0000256|RuleBase:RU365057};
GN ORFNames=I302_07420 {ECO:0000313|EMBL:OCF23069.1};
OS Kwoniella bestiolae CBS 10118.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296100 {ECO:0000313|EMBL:OCF23069.1, ECO:0000313|Proteomes:UP000092730};
RN [1] {ECO:0000313|EMBL:OCF23069.1, ECO:0000313|Proteomes:UP000092730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10118 {ECO:0000313|EMBL:OCF23069.1,
RC ECO:0000313|Proteomes:UP000092730};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus bestiolae CBS10118.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10118 {ECO:0000313|Proteomes:UP000092730};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for 60S pre-ribosomal subunits export to the
CC cytoplasm. {ECO:0000256|RuleBase:RU365057}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|RuleBase:RU365057}.
CC -!- SIMILARITY: Belongs to the SDA1 family. {ECO:0000256|ARBA:ARBA00005783,
CC ECO:0000256|RuleBase:RU365057}.
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DR EMBL; KI894024; OCF23069.1; -; Genomic_DNA.
DR RefSeq; XP_019044139.1; XM_019194016.1.
DR AlphaFoldDB; A0A1B9FWC7; -.
DR STRING; 1296100.A0A1B9FWC7; -.
DR GeneID; 30211819; -.
DR VEuPathDB; FungiDB:I302_07420; -.
DR OrthoDB; 5482564at2759; -.
DR Proteomes; UP000092730; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0042273; P:ribosomal large subunit biogenesis; IEA:UniProtKB-UniRule.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IEA:UniProtKB-UniRule.
DR InterPro; IPR027312; Sda1.
DR InterPro; IPR048292; SDA1_C.
DR InterPro; IPR007949; SDA1_MD.
DR InterPro; IPR012977; SDA1_N.
DR PANTHER; PTHR12730; HSDA/SDA1-RELATED; 1.
DR PANTHER; PTHR12730:SF0; PROTEIN SDA1 HOMOLOG; 1.
DR Pfam; PF21638; SDA1_C; 1.
DR Pfam; PF05285; SDA1_dom; 1.
DR Pfam; PF08158; SDA1_HEAT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365057};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|RuleBase:RU365057};
KW Reference proteome {ECO:0000313|Proteomes:UP000092730};
KW Ribosome biogenesis {ECO:0000256|ARBA:ARBA00022517,
KW ECO:0000256|RuleBase:RU365057};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365057}.
FT DOMAIN 75..463
FT /note="SDA1 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08158"
FT DOMAIN 573..742
FT /note="SDA1 middle"
FT /evidence="ECO:0000259|Pfam:PF05285"
FT DOMAIN 762..808
FT /note="SDA1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF21638"
FT REGION 535..651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 739..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 543..559
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..574
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 616..636
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 739..766
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 811 AA; 90733 MW; B17537AD8040D0E0 CRC64;
MVKSRASRGI LLTSNLPQLQ NLIKRDPEGY KEEFLTQYNH YLSLLKLQQV SSVTSTSTNS
TTDKSNELFG DLITFISQVA QCYPVETKEL PLQLKGLLLG AEGGQTVKGD LRRTVVKNLV
MLRNKEIIDS IELLQILLPL LPQVPSALRG VIRHTILTDI KTSNQKTKNH RLNRVVQSLL
FGMVESGMGA EVVGDKGKGK GKEKGGEAMW AVMMVKELWK KGVWNDAKTV SIVALAAFHP
NTKVQSAALH FFLGSDNEDA EDTDSDEEDI REARRGVKKM EHRMEVGKSG RKKEKMLAQM
KRETNKKRAK HAAGLGHTPN FPALELLHDP QTFGEKLYDN LHKHDKIYSL DHKILIMQLL
SRVMGTHKLC VLGFYSYIIK YLTYHQLQVT LILVSLAQSV HELTPPDVLT PVIRKLAQEF
VHPGVGAEVI AAGLNAIREV CRRQPWCMEE DLLSDLIEYR KSKDKGVVTA SRGLLQLFRE
VNPGMLKKRE RGKAASMGLI GSQVLAYGHS KDAAEGIEGL ELLEEHFAQM RKEANGGEFD
DNSDVEMGVD EDDEQGWENW DVNSESGSES SGWEDVSSGE EDLEISDSDD EEDRKRDRKE
KKLKKKGKAV VKNEDEEDSD SEDEKDDGDE DVDMDDDAKS TVSAATTAVS QDTKKLSLLA
QQKILTPADF ALLNELRLKA AKSLAESGGG SGAKRKLAAL EASKRHVDAD ESERFLTEAE
ILGPRKKVKA TWEERMELVQ KGREGREKFG SLKGKKKKET PSSSTNREKA RNKPIMMALH
SNKVMQKKKA SLRDKQIKLR AAIDKQKKLK H
//
