ID A0A1B9G179_9TREE Unreviewed; 3085 AA.
AC A0A1B9G179;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=FMP27 GFWDK domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=I302_06231 {ECO:0000313|EMBL:OCF24770.1};
OS Kwoniella bestiolae CBS 10118.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296100 {ECO:0000313|EMBL:OCF24770.1, ECO:0000313|Proteomes:UP000092730};
RN [1] {ECO:0000313|EMBL:OCF24770.1, ECO:0000313|Proteomes:UP000092730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10118 {ECO:0000313|EMBL:OCF24770.1,
RC ECO:0000313|Proteomes:UP000092730};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus bestiolae CBS10118.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10118 {ECO:0000313|Proteomes:UP000092730};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI894022; OCF24770.1; -; Genomic_DNA.
DR RefSeq; XP_019045840.1; XM_019192843.1.
DR STRING; 1296100.A0A1B9G179; -.
DR GeneID; 30210630; -.
DR VEuPathDB; FungiDB:I302_06231; -.
DR OrthoDB; 607689at2759; -.
DR Proteomes; UP000092730; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR019443; BLTP2/FMP27/Hobbit_C.
DR InterPro; IPR019441; FMP27/BLTP2/Hobbit_GFWDK_RBG.
DR InterPro; IPR019409; FMP27_sixth_RBG.
DR InterPro; IPR019415; FMP27_SW_RBG.
DR InterPro; IPR019449; FMP27_WPPW_RBG.
DR InterPro; IPR045167; Hobbit.
DR PANTHER; PTHR15678; ANTIGEN MLAA-22-RELATED; 1.
DR PANTHER; PTHR15678:SF6; PROTEIN KIAA0100; 1.
DR Pfam; PF10293; DUF2405; 1.
DR Pfam; PF10351; FMP27-BLTP2_C; 1.
DR Pfam; PF10347; Fmp27_GFWDK; 1.
DR Pfam; PF10305; Fmp27_SW; 1.
DR Pfam; PF10359; Fmp27_WPPW; 2.
DR SMART; SM01214; Fmp27_GFWDK; 1.
DR SMART; SM01215; Fmp27_SW; 1.
DR SMART; SM01216; Fmp27_WPPW; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092730};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1408..1507
FT /note="FMP27 SW motif-containing RBG unit"
FT /evidence="ECO:0000259|SMART:SM01215"
FT DOMAIN 1525..1683
FT /note="FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit"
FT /evidence="ECO:0000259|SMART:SM01214"
FT DOMAIN 1965..2412
FT /note="FMP27 WPPW motif-containing RBG unit"
FT /evidence="ECO:0000259|SMART:SM01216"
FT REGION 272..294
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 888..908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1378..1405
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1732..1762
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2088..2110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2738..2773
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2931..3085
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..293
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..908
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1378..1396
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2743..2773
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2931..2963
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2964..2983
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2984..3019
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3020..3040
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3061..3085
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3085 AA; 347405 MW; 652B5EBCEBBD96E1 CRC64;
MSLSTQLAHP QIYLTSTILV LLLLIWTRGF SSPFYLLFSI LSIWWKITRF SIKWTFYLVI
PSLLPQYYIL WPWVIRHKIP QARASRFSIV GAFRGLEWKK DNVNVRAESG AWRWGGRKAE
GVGYFVYRVE DVVVRARSSA GRTPQSNGPT GTTLPLRSRL PPLLRSMFQA DGVLVKNFIW
IVQVVIHYIP GFARLLSLEL KNCRIILEDF DNIELVFDEF SFGAMINFQG VAEAEATNAY
QANTPTPSPQ AGCQEFMRQN PLIYSPSIAE RGRKSPLTFS PPSSPPWSPV SSPPMSPTFG
SLAVPDPILA GIPDRQRSTS RLADARRRAS VFSSSTSATA GYVWNRVTGR LYGSIVGTAS
VVNVRLVQPK SSSTHHSQHV SSQPLSNSTS FRSIHALLRH NTAAHLPSIS SDGYECFMGI
SGRTKASLGL GFGPKKGLWG EDTLEGQVQA GEITGKIEGV QKLLDMAKRH KRKAEKRPVQ
IKSSRWSSRG WSRTVLRAIK SVNVNLQKFT VVHYLSSPSN SSKHFGSPPS SPDRYTVSVD
LTHLDLTLIA ADSSNNERAR NAFGTNSNPD SKIRGVGFAI SWESINLDCL APQETSEEKS
QLFVIQNGTL DGFSSWRPAG WKREELLFSS DPNLALIVLR GEVGSINTAI DLQLLHELAA
AWRLTHPKEK AQEAVDHVQQ QSQHNLPPRL RMVFDVGHIS AHLADRLSEN TTAVTFDSDG
VHLGCFTAFS DLIGRRRDKA TTKKAFEDEE KIRESRNKLK CPSLAVASAD LPPEARRSPD
RPTAFLYEDY STCLRGDAQM NIEPIRIKIK LSDDRFSELA TVGRMHGMVG GDVFGRREVI
DGRGFLESTS FDWSSLSSSL DLGIDEGIHI NLWRKDVIDA LIAMGKAHQQ GSPSHSSSST
TSNKSPLARL PSGMSARVSL GNINLFVGHE DINPSLDTKN GPPVRGTWIQ TSAVFEYALY
RHYAQAFPWR HQLTAPTRVK LHLPEDITVQ ALAFASRYRP NDGSAALTSL VVEDLVVQPI
YNGQRFTARG GTRQKLVVKA IPPNDVKDDK CHWGSQRLWA RLKALRDKDI QSWPEDRRRE
TSLPSLESYI PRLDYNVPPI EATGTEQAQR PWLRIKNTRL HLTIQQTKAD VDTEFKVTAR
FDNVGVISNY SHLYSNLHTA LTLRKLVNGW KRPKGIDNTP RQPSNFSISI LIPNLTAHFA
FPLKEQIYVY SSHVSITKPP SKGLSVSADQ ALVYVPSPTV IGDWEELGRI KKLAVHLSDP
GAPLVINPKI EAIRVRIPHK YLMNSLILDI NVTIKALKVI LRNFFKSNEF ITRHTSLAEE
PKHVPNICLE IGYMSFEAKD DAADTNLNLI WRAGFLEQAK RNSLEDAFAK KIALMNSSNS
SSEDSLHNSG SNRPEPKLTK KATVDAEDAR QRLDAYLANN WIKRMRAAKH EQRRREAITL
KPMHGCGPNI KLPINIVPSS QTAPLFRATF QNVNFSVSDP GLDRKEIIEY MGKVSSPFDE
GTEFSLMVPL KLDWTMSEAK CTLRDYPLPM LKIQPSPCVP SQNGTISPTF QMTSTIIIAE
EFANDDSTVY VPVEILPKEC GGPNLEGFSI DVAKTIMPVK MYGEPRFKVN SKKTTEFTWG
MSYQFGVQDF VKVIETFSHP PRDPSPKLGA VDKMRLICHL KPIVEFEGPV HLHLKGTFDP
YQLTGLGAGF ALAWKGNTKL LINQPNEDRE AVQIVADNLL VAIPDLTALN DSAATGSPTR
SDDTPSPGST ITPGTDESES SLINRRYTKP CAKFVNGTKV GFGFGRERTC RPWDCACGCG
DEDNHLHRKC RMFDFLPHQK VILRSPEAIR KEEERPVDSY EGFRSDYTHF SVSVIAPTHP
FTEQRLESED PAHVNSFHCT PKAMHHFLRW WRLFNHVTWL PTREGPYEGG SPGSLYIGSR
RKSKKESKPL ATLKYRFDLK PLYVSHIYPQ VTKELWAQGK SESLGIKVRA GRLLFDAHQR
LQEKMEYKEK LQEFRANTHR PLYAADVVAD DLTIKGIRAH FIERVRLDPQ LRESLPRASE
LPQETKVWFD LTDYIDADRK PLDEDPQVEI VDFGDCPHVY FCRRTNTNDL NENGKHGNNS
NGTSRSHGIE SSKFGFEKTH HCYLDEAETR AEVDERIVKK RIAELQARLD SYPTTNTAEY
RNDQAITQNA INLLQKNLID IERDNPDQYD DSGKRKSLER PFQDTIEVHS PRLFYNDLSR
PLLWAYMYSV SDRRKEEYHV SHVSLRNYRE QFIRRRKRFL EALDNSETHE NNVPEDMVGE
LAHSLVEKPL DSIFQCLNID NNPAAYRTAS LGLPAECTLK PKLQISIFKP QIALRSNATE
SAIVLLAVQE ASIKRFSVED PETGDDMTSD VLTRTYALLK EVQAFYPTTE ALNRERSGSI
SRGLDFVPLE IFLDAKSQAT DYDRILLRTN LAGSYDKFNR LRIPRQLKWP KAINENGDPI
EHLRIHQDLM TIITPQIKLF ATSKHYDALY TIITDLLIYS DPDHQHRNQA VKDFSRQFDS
SDRDTNRLLV DIHTLQQTMR HLMELQRGYE TNLEKLEEAG KDELFKIRAD LAEGYESLYT
INAMIANTLA KDDARAFLKN ALRLDIRLRE VSWRMLKEDC ISSLAQVTMS SALCSYSNNK
NGSTDCALVL GSVQVNNLAP DAKFEGMIVS QDNSSWKKKA KSVFAKVYWS SYPPIGGIPV
FPEVDVELAS VRFGIEEKMG HQVVDYIFSD RIRRRRDKAK LAQQQLSHTN GSSTPNANAS
PLNGKADTRS ISSRATLSTD DLSVASSTRN ELYPLSRSRS QVSINSHNDV ETISTYGNSR
SNDDAKEMRE RASTNRYFGK ISFHRMNLTL SYTRDDTRKH STLSMPECAN FSFKAPDLVY
TGKYWVPEEI FEHVKKDLKS AAFAQWSELI PQIFKQTSLF RSKRTLRNLT ERTTKAVGNN
LPSPLKHITT HTSTSTSQPF SEDETGVERI KSGSVRSHHS PSHSHETSPP MMIPQDQVDT
PSTFSTNGSG SGSRSVRSNG GVKSDEEEDE HEHREKGLKG LLGKFGVGKH HNHSTDELSR
SRSRVTSNSS LDRKHPTQTP SVSFG
//
