ID   A0A1B9G253_9TREE        Unreviewed;      1180 AA.
AC   A0A1B9G253;
DT   02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=CNH domain-containing protein {ECO:0000259|PROSITE:PS50219};
GN   ORFNames=I302_04922 {ECO:0000313|EMBL:OCF25112.1};
OS   Kwoniella bestiolae CBS 10118.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC   Tremellales; Cryptococcaceae; Kwoniella.
OX   NCBI_TaxID=1296100 {ECO:0000313|EMBL:OCF25112.1, ECO:0000313|Proteomes:UP000092730};
RN   [1] {ECO:0000313|EMBL:OCF25112.1, ECO:0000313|Proteomes:UP000092730}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 10118 {ECO:0000313|EMBL:OCF25112.1,
RC   ECO:0000313|Proteomes:UP000092730};
RG   The Broad Institute Genome Sequencing Platform;
RA   Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA   Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA   Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA   Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA   Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Cryptococcus bestiolae CBS10118.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000092730}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 10118 {ECO:0000313|Proteomes:UP000092730};
RA   Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA   Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT   "Evolution of pathogenesis and genome organization in the Tremellales.";
RL   Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KI894021; OCF25112.1; -; Genomic_DNA.
DR   RefSeq; XP_019046182.1; XM_019191552.1.
DR   AlphaFoldDB; A0A1B9G253; -.
DR   STRING; 1296100.A0A1B9G253; -.
DR   GeneID; 30209321; -.
DR   VEuPathDB; FungiDB:I302_04922; -.
DR   OrthoDB; 198927at2759; -.
DR   Proteomes; UP000092730; Unassembled WGS sequence.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   InterPro; IPR001180; CNH_dom.
DR   InterPro; IPR032914; Vam6/VPS39/TRAP1.
DR   InterPro; IPR019453; VPS39/TGF_beta_rcpt-assoc_2.
DR   PANTHER; PTHR12894; CNH DOMAIN CONTAINING; 1.
DR   PANTHER; PTHR12894:SF34; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 3; 1.
DR   Pfam; PF00780; CNH; 1.
DR   Pfam; PF10367; Vps39_2; 1.
DR   PROSITE; PS50219; CNH; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000092730}.
FT   DOMAIN          82..380
FT                   /note="CNH"
FT                   /evidence="ECO:0000259|PROSITE:PS50219"
FT   REGION          24..48
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          406..479
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1109..1133
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        407..421
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        464..479
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1180 AA;  129601 MW;  F2DF403EC22F071E CRC64;
     MINDTPHFTT QPVLSDLYQS KDLLDFSGPS TPPRASTSSP SASPSTTSLF SSATSIASAA
     TRRAAAAGLT SSPSDPSSSS TAKEVRCVEG YGQNLYIGNS DGTVEWWICE AASAGNGMNG
     WGMKHRHTLF PRRPVNRVYI LPKISKILMI SDGTLHALSL PNLEPLPSSH VPPLRGVVSV
     ILDDEELEWG GPGSEDPNAQ MTVVVVRRKG LGVYKLGNRM NSVKEIPLPS SPTHHALFSS
     FLCAAITSGQ EDTQQTLYSI IDLSDASLTE VLPVSQIDPA VAEFEPNPNI VVIPGENEFL
     VTSYTGSSTM GVFLNGQGDP VRGTMEWPSH PISIAVESEY IIALLRDQTI TIHSLADLEK
     PTQVISLDPS LNAVSLTYSP YGISVRDIFR DERLVPYKLK LLGGKLAPKK PTEEPKEALP
     QVEDLPNDPL PVEEPLSPEV ISPVNEDPPS GSGLTPPSSP KPHHRHPTTL QNATSSTSTI
     GPFSTAVSET LIVCPHSIVS LLPTSTIMKL QSLCSERQFD EAISLVDDER RRGRRGEIDV
     DKATHHNTMK FLHLYLALHL FEEALFDKAL DYFTRSKVDP RILVRCFGGL RGKLIGSEEG
     VEVYEGVREV LERMGGVEDI ISTSLKRNYS PHVQPNTATA PETSVLRLAM MEEAKDMLTE
     FLRKTRASRR KGGGARGVDS RKIDIVIDST LAKLLADKGT TNELLALLAA PNDCVSSELE
     PFLAQTPYVL ATVMRTQGRV DRVLELLKDI AESDTPDPIC EDPVEELAQQ LESIKDPEVF
     LEYALWLVKK KPSRGLSILM AQNTKNGIKL DDLSLVKQLG DIDRDTANRY LEFAVVTKKS
     PSRALHEQLL GVLLDEVEEL CRDEGVKYHL EELDAEYRLE PSPRPFITFL ADIAPDTPIK
     RNRLKLMLFL QGSPFFDLEG AAKRLDGVGE LKFELAVVYG RLLRHRQSLS LLAITIGDSI
     SAQTYCQTKG EIIPPKISKA VAKQVRGLDP WASLIEVGRK KSQGQVKEDE MRGLVRELLG
     VYMSDSKGTS KQAAALLNAQ SVHLDVLEVL GQMPNDWPLD EVSSFLKRSF RRGLHERSTW
     GVLKAISAGQ NMEVSEEYLD RIRRIPPIIR TSSTDGHDDN GLTPPDEGSI PETEWGTFEE
     KSMVEGVLGE KDGVIRRIEG EVGSKEGYIV DREDGEEGLV
//