ID A0A1B9G6S1_9TREE Unreviewed; 542 AA.
AC A0A1B9G6S1;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 22-FEB-2023, entry version 22.
DE RecName: Full=DNA polymerase epsilon subunit {ECO:0000256|PIRNR:PIRNR000799};
DE AltName: Full=DNA polymerase II subunit 2 {ECO:0000256|PIRNR:PIRNR000799};
GN ORFNames=I302_04414 {ECO:0000313|EMBL:OCF26727.1};
OS Kwoniella bestiolae CBS 10118.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296100 {ECO:0000313|EMBL:OCF26727.1, ECO:0000313|Proteomes:UP000092730};
RN [1] {ECO:0000313|EMBL:OCF26727.1, ECO:0000313|Proteomes:UP000092730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10118 {ECO:0000313|EMBL:OCF26727.1,
RC ECO:0000313|Proteomes:UP000092730};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus bestiolae CBS10118.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10118 {ECO:0000313|Proteomes:UP000092730};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Participates in DNA repair and in chromosomal DNA
CC replication. {ECO:0000256|PIRNR:PIRNR000799}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR000799}.
CC -!- SIMILARITY: Belongs to the DNA polymerase epsilon subunit B family.
CC {ECO:0000256|ARBA:ARBA00009560, ECO:0000256|PIRNR:PIRNR000799}.
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DR EMBL; KI894020; OCF26727.1; -; Genomic_DNA.
DR RefSeq; XP_019047797.1; XM_019191049.1.
DR AlphaFoldDB; A0A1B9G6S1; -.
DR STRING; 1296100.A0A1B9G6S1; -.
DR GeneID; 30208813; -.
DR VEuPathDB; FungiDB:I302_04414; -.
DR OrthoDB; 166885at2759; -.
DR Proteomes; UP000092730; Unassembled WGS sequence.
DR GO; GO:0008622; C:epsilon DNA polymerase complex; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006261; P:DNA-templated DNA replication; IEA:InterPro.
DR InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR InterPro; IPR016266; POLE2.
DR PANTHER; PTHR12708:SF0; DNA POLYMERASE EPSILON SUBUNIT 2; 1.
DR PANTHER; PTHR12708; DNA POLYMERASE EPSILON SUBUNIT B; 1.
DR Pfam; PF04042; DNA_pol_E_B; 1.
DR PIRSF; PIRSF000799; DNA_pol_eps_2; 1.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR000799};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR000799};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR000799};
KW Reference proteome {ECO:0000313|Proteomes:UP000092730}.
FT DOMAIN 291..493
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
SQ SEQUENCE 542 AA; 60610 MW; FF5666D67E9B4A9A CRC64;
MVKLMRAAIV KVFSTKHSLT LPAAALGYIE QVLLENEIPE DEWIVGLEFW AREYLKGEDS
SSLVSLPALK RAYESLQLGT TDDTAQADPS EVNVESHFSV IDSFDMPPVH FDAVRGGFTT
SKPKPSIAGQ ASSRSAFLRE RWGIIKEIIL RNENFTPPAI GGHDRSNYLK LTSTRNLLGR
AGQLFLLFGM LSRDPEGRLC LEDGEGRVVL DMEDAVPGEG LFTEGCMVLI EGEYTIDETV
RVLAMGHPPS EKRDVARGLH GHVDFLGGGA MSLKEEQKYQ PSILANTQVS FVVLSDVWLD
HPRTMPALRR MLEGYAEAVE YRPMAFVFCG NFSQKGWEGE GGLKRYTNGF NALTDLLLEF
PLLHSSHFVF VPGPLDPWSS TTLPRPAIPS VFASRLTQRV PKARFVSNPC RLRYFGMELV
ICREDLMGKM VRNLVGVKKE GEADMKRYLV QTILDQTHLS PLPISIRPTL WEYDHALRLY
PMPSALVLAD KYERYELTYE GCHVFNPGRF VGSGGEGGGE FEWSMYYPAT GRSERSALTL
DQ
//
