ID A0A1B9GDU0_9TREE Unreviewed; 757 AA.
AC A0A1B9GDU0;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Polyadenylation factor subunit 2 {ECO:0000256|ARBA:ARBA00026154, ECO:0000256|RuleBase:RU369034};
GN ORFNames=I302_00699 {ECO:0000313|EMBL:OCF29203.1};
OS Kwoniella bestiolae CBS 10118.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296100 {ECO:0000313|EMBL:OCF29203.1, ECO:0000313|Proteomes:UP000092730};
RN [1] {ECO:0000313|EMBL:OCF29203.1, ECO:0000313|Proteomes:UP000092730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10118 {ECO:0000313|EMBL:OCF29203.1,
RC ECO:0000313|Proteomes:UP000092730};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus bestiolae CBS10118.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092730}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10118 {ECO:0000313|Proteomes:UP000092730};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for 3'-end cleavage and polyadenylation of pre-
CC mRNAs. {ECO:0000256|RuleBase:RU369034}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU369034}.
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DR EMBL; KI894018; OCF29203.1; -; Genomic_DNA.
DR RefSeq; XP_019050273.1; XM_019187395.1.
DR AlphaFoldDB; A0A1B9GDU0; -.
DR STRING; 1296100.A0A1B9GDU0; -.
DR GeneID; 30205098; -.
DR VEuPathDB; FungiDB:I302_00699; -.
DR OrthoDB; 5487329at2759; -.
DR Proteomes; UP000092730; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0031124; P:mRNA 3'-end processing; IEA:UniProtKB-UniRule.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 3.
DR InterPro; IPR045245; Pfs2-like.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR22836:SF0; PRE-MRNA 3' END PROCESSING PROTEIN WDR33; 1.
DR PANTHER; PTHR22836; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF00400; WD40; 5.
DR SMART; SM00320; WD40; 7.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 4.
PE 4: Predicted;
KW mRNA processing {ECO:0000256|RuleBase:RU369034};
KW Nucleus {ECO:0000256|RuleBase:RU369034};
KW Reference proteome {ECO:0000313|Proteomes:UP000092730};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT REPEAT 204..245
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 246..287
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 288..329
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 377..409
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 507..757
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 507..526
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 649..674
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 689..721
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 723..738
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 757 AA; 80444 MW; 0FA6B0B9AC974ABA CRC64;
MVSTNSIAGP SRSRGQDTWA PTKYLEPLHP DNEEVHEQAA YQAAVTRQGG DDRKRKIKPR
RAVDYQGGVI KWRMLTKMKG IKDYRPAIHP NPSDIVNLLP PVALRLNPST SICDQWVHTS
INKERSPTRV VQWTPDARRL LTGNDKGQFT LWNGASFNYE SITQVHDDSI RSFTYSHNGQ
ALVSTDKLGM IKYFTPHLTN IHGFQGHREA CHGVSWSPND ERFVSGGDDG LVKIWSYREA
REEKVLSGHG WDVRCVDWHP TKGLIVSGSK DMLVKFWDPR TGKDLSTLHS HKSTINTCVW
SPEGHLVATA GGDAVIRLFD IRTFRELEAM KGHTKEINCL EWHPIHHSLF TSGDSAGTIN
HYSLTSPTPS EPITSLASAH EDAVFSLSYH PLGHLLCSGS KDFTARFWQR ARPAGGHEKD
RWHLGEERAM NAKFEEKDAG WGGMATTTTT SGVEKEKEGE VGLPGLSNLV AAVNAKVGPG
VGIAANGSGS NTPEPPFLSG TGLPGLGAYT NNRESSTTTS PLNIPHMDQN GPPPGMAGGG
RGRAPLPSQG DMLRQNNMGE GGFDAGNRRG GDNRRGGGSA GGGGRYGGQR GGNGTGNGFN
NGPGGGAGGQ GGYGGGSAAP GGYNQNGAPG GYGPPQGYGG GQAQAQSGYG GPPPLQSYGS
QSQNQNQNQV QFSGYAPPGA AGGYNQPPGP GPSSGQVQGQ GYGPPQGYGA PSQNQNQYGP
PAQGYGAPPP PPQQQGRAPL PQGYPQHGFD GRGNGWR
//
