ID A0A1B9GL16_9TREE Unreviewed; 902 AA.
AC A0A1B9GL16;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=DNA (cytosine-5-)-methyltransferase {ECO:0000256|ARBA:ARBA00011975};
DE EC=2.1.1.37 {ECO:0000256|ARBA:ARBA00011975};
GN ORFNames=I316_06668 {ECO:0000313|EMBL:OCF31663.1};
OS Kwoniella heveanensis BCC8398.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296120 {ECO:0000313|EMBL:OCF31663.1, ECO:0000313|Proteomes:UP000092666};
RN [1] {ECO:0000313|EMBL:OCF31663.1, ECO:0000313|Proteomes:UP000092666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCC8398 {ECO:0000313|EMBL:OCF31663.1,
RC ECO:0000313|Proteomes:UP000092666};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus heveanensis BCC8398.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCC8398 {ECO:0000313|Proteomes:UP000092666};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01016}.
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DR EMBL; KV700132; OCF31663.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B9GL16; -.
DR STRING; 1296120.A0A1B9GL16; -.
DR Proteomes; UP000092666; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 2.30.30.490; -; 1.
DR Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR043151; BAH_sf.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR10629; CYTOSINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR10629:SF52; DNA (CYTOSINE-5)-METHYLTRANSFERASE 1; 1.
DR Pfam; PF00145; DNA_methylase; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51679; SAM_MT_C5; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01016}; Reference proteome {ECO:0000313|Proteomes:UP000092666};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01016};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01016}.
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 26..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 514..538
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 712..735
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 79..111
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..538
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 513
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ SEQUENCE 902 AA; 100131 MW; 278E305700EF182B CRC64;
MSDPRRSSRP STSLGKRMRA LSVISVISEE DEEESAGADT SKRDSKARSS EQALPPSPTD
RVKRARSDTS RVAKAPIKAT ETPSTTPWTS TSNQTHHSRV TGRSDNRAVW STDRNPIHPG
EEVAVKVDGV DDAIRLSSAP YDLILIRSIY TLKFHDSGIP SKSYVHAQYL DKPTSIDGRS
ARSYRQGELF LKHANCQDFA LKLIIEGTKL DFELIKSSAT RRRDTKHFAQ FVDEWTASTI
RVPSPALDFH GCDACHSRDK KQYAEVVTIE KDAVRVGEER YHLFDFVFID PGVQGAPYMI
GHLISWTEKK GSVEVNLRMM ERIQEVPGMS AYVSERHLVA SHKHLFFPAT RIVGTAFVFG
SEDALRKGAP GCKSAFWCTH RLIENDRGRE VSLPLQTPLK SCSSCLNLQC HYRHDIKSCL
EAARFPAADC YSGAGGFLLP GLDIFDWQSA CDIDVVACET LRRLKPKVPK LKIHHGSVEE
LLHRSLDRDA HDTSSRRFPA RGSTFLLTGG PPCQGHSRAS HANNNTNGEN SSKAGPTDDR
NSEMFVFLAL VAHTLPYVVI LENVGAFKDD KAELSQENAD GNFARRAMRE LTSMGSVQLM
LSSLQTLLTD STYRVARRYA VRLAVINSRA YGSPQDRHRC FILAVQRGLP LPELPAPTHA
VPSPMATVFK DKNGRAMPFY LGDRRATRGT GIHPPVTISD AISDLPVFEY HSRGTDQRPR
RPIFSGSRDP AKGNGTKCGF AKPVAYASPP LNDFQRAKRG SNTQVNDHYT SYCTPGALDI
IFNRSKLPNA RGCERRAVSN EGFSTLLTNS APGGKSTAVI HPSQERKFTT AERKRAMGWP
DCFKLAGTPL DQDRLTGNGV CFESVEAIYQ SIVETIILPW WIKAGKPKER VYEKFVADYP
IL
//
