ID A0A1B9GX21_9TREE Unreviewed; 1868 AA.
AC A0A1B9GX21;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN ORFNames=I316_02636 {ECO:0000313|EMBL:OCF35581.1};
OS Kwoniella heveanensis BCC8398.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296120 {ECO:0000313|EMBL:OCF35581.1, ECO:0000313|Proteomes:UP000092666};
RN [1] {ECO:0000313|EMBL:OCF35581.1, ECO:0000313|Proteomes:UP000092666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCC8398 {ECO:0000313|EMBL:OCF35581.1,
RC ECO:0000313|Proteomes:UP000092666};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus heveanensis BCC8398.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCC8398 {ECO:0000313|Proteomes:UP000092666};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI669498; OCF35581.1; -; Genomic_DNA.
DR STRING; 1296120.A0A1B9GX21; -.
DR Proteomes; UP000092666; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd13246; PH_Scd1; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR033511; Cdc24/Scd1_PH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR036465; vWFA_dom_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR10579; CALCIUM-ACTIVATED CHLORIDE CHANNEL REGULATOR; 1.
DR PANTHER; PTHR10579:SF43; LOW QUALITY PROTEIN: EPITHELIAL CHLORIDE CHANNEL PROTEIN-LIKE ISOFORM X1-RELATED; 1.
DR Pfam; PF15411; PH_10; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF53300; vWA-like; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Reference proteome {ECO:0000313|Proteomes:UP000092666};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00175};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00175}.
FT DOMAIN 885..941
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT REGION 1..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 165..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 346..400
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 415..463
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 563..585
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 598..698
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 710..867
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 961..1025
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1056..1111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1605..1639
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1801..1828
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 120..137
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 165..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 622..694
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 725..752
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..807
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 826..867
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 967..987
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1010..1024
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1074..1109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1868 AA; 202027 MW; 45D2CFFDE936E5F2 CRC64;
MVPGQSSFDF GDGSSSSHST SPSAAWRGLR RALSLNSGSS SHASASRRSS KATTASTIRM
SRQLMGVTSG QQQHGRGVTG TDNDHRQSIT STPLSGGSSS QGSESDVRLS GVVAVAEDLG
AGRHGEKSAK IRSDNDGRGC GGRPVAIGLN TSAFASVGSF GTTSTMLSRD RDQEAPSGPS
SPCDTDRFSL SDWSNIPFPK PPSLTPPRSS SAGAAWEEDQ EANGDNDTTN QGDGLSTQDE
LEHELIITIQ SPFAPFAHAH DGILSREREL AVDSPPSHVD ESPTDPLFPF HSKSEYNRPI
SVSGSIDSEL SKPTTPVSVS VSVCAGVSTC SDSPYCPPSP ALTPSPHLSS ANSPVLTTPG
VRPSPSQPST PILNGQDEDN SNVTTPSSSH ADIRTHTPTT KHTTVLLLGS LNLSPLTPET
VKSSTPAITP KSSYSHTHPS NQYQHENGNE NEHGQSIPPS SSTAAPLFEI QQTETSTSNR
IEQSPLVLLS TASKTIATDS NLISPRQRTI STPSYTTSPS LLTSLDDPIV LRDTQHQHCP
KPQSVHNHDR APTKDNHIGE RQLQVAQDDS MVYSEQESRQ GRERDWAYDN QVTRDRHPAQ
GAANQVPPPP QSFHHHHKAQ PSVPYSTRTI SSLGHNSRLS VDPTDSLSPP PSYGHFSNSS
SSRRNSKYTA FSGSSSSSIH SYSTTDSSSY RGHNQHWHLG ERPDISTVFE ENSGDADADP
EYEEDEHVHD SNKDQYEFVV PLKSREHSAS GDSRYPTLHT QTSSNTLVNR PSSRSTPGYF
SRERSSTINS ANGTITSTGS GKTTSKPVHP FANAVVRPTS PPPLPSSKSH NKFLSPQHPR
RPSSPTLQSS RSSPNLAESY KMSNQPTHQV TLVSTEDDRD DEETCPVCVE SLSFTYRLPG
EKPHIVPECG HALHEECFVT VYGDVPPEGS KKVLGVCGVC RQPMKMADGA TKRDKLAMLM
GRPGQNAGRK PSQSAPSVRS TSGRGQPSSP PPVDPNADDP LEDRTISSSR SMHSEGSQPK
VVVPSISIRS EFPSIAKGHR KGKQVITAMV TVEVPPAENK GRYPPKARPN GMSRTASHED
QFSPQLPPSP RSASDSSVVP STARSAPASA STPDPFAHVV YDLRHRVVDY KTSGLDQLGS
LKLFDLLCVR KGQLIREFHV YLFQEALICV SEEKKSGLRN IFSSSASIRS DHSSGSHHGR
GVLKLKGRIY VRHVRKVIDT SVPGELSLTI TMEDESLDSF ILCFKDRSSH ETWRSTINRL
LEDVKGGSQN KVQKMIGSAA PRSANASSSA NGSALGMSFG DLASPSTAGF AVTPASSTFT
HTEPTPGDLA YEQPLAPIHT PIDLVIVLSL PAPSSNSQLP LKVKLMKSSL SFILALLGPK
DRISLVTCEM GVNGLVRKTP FLSPCRHESR KRLEAFVETL GTGRTAKDEF EASVGREERF
DVVTAVNVAL DVVLQRKVKN PISGMVLISD TSDVIKRAQM DLVTARLDAA NVPVHALGYG
RSHDPSPLWM ISNHTHGTYT FVKEWYHLRD SLAGVVGGLM SIAMDNMKLH LSCQENDFHV
TKVSGTTSAI VSKNGKDVDI ELRELRHGEI REILVELDLE VEDGSNEQRY SGDGSSESGR
LSERRADGSQ NGSSIRKAPS FNVDRGLGLD TLSVGDANAL RDVVYEDALI DEVPVVEVDC
SFHDPGAGRS VARLAHPVLL TVAILPSNAP PSSSPADPMI VRRRMELLAS DMITRALLIA
SRKNFTHASR ILRETKRIIE TIVDGLRAHV SQQHVNANGQ GGRSKREAQT LFAVEGLMGT
VQDLDMLLDG LEEHKEMFER DHRNYSAQQA GVLRAQRSWT TRTPTERTYA TKEVQYIIAL
SGEWQGRV
//
