ID A0A1B9H4D1_9TREE Unreviewed; 1072 AA.
AC A0A1B9H4D1;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 13-SEP-2023, entry version 17.
DE RecName: Full=Signal transduction-related protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=I316_00343 {ECO:0000313|EMBL:OCF38119.1};
OS Kwoniella heveanensis BCC8398.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296120 {ECO:0000313|EMBL:OCF38119.1, ECO:0000313|Proteomes:UP000092666};
RN [1] {ECO:0000313|EMBL:OCF38119.1, ECO:0000313|Proteomes:UP000092666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCC8398 {ECO:0000313|EMBL:OCF38119.1,
RC ECO:0000313|Proteomes:UP000092666};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus heveanensis BCC8398.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000092666}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCC8398 {ECO:0000313|Proteomes:UP000092666};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SYG1 (TC 2.A.94) family.
CC {ECO:0000256|ARBA:ARBA00009665}.
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DR EMBL; KI669492; OCF38119.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A1B9H4D1; -.
DR STRING; 1296120.A0A1B9H4D1; -.
DR Proteomes; UP000092666; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd14475; SPX_SYG1_like; 1.
DR InterPro; IPR004342; EXS_C.
DR InterPro; IPR004331; SPX_dom.
DR PANTHER; PTHR10783:SF103; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1; 1.
DR PANTHER; PTHR10783; XENOTROPIC AND POLYTROPIC RETROVIRUS RECEPTOR 1-RELATED; 1.
DR Pfam; PF03124; EXS; 1.
DR Pfam; PF03105; SPX; 1.
DR PROSITE; PS51380; EXS; 1.
DR PROSITE; PS51382; SPX; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000092666};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 611..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 654..674
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 686..706
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 835..859
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 879..899
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..518
FT /note="SPX"
FT /evidence="ECO:0000259|PROSITE:PS51382"
FT DOMAIN 768..960
FT /note="EXS"
FT /evidence="ECO:0000259|PROSITE:PS51380"
FT REGION 36..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..436
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 951..1072
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..124
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..186
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..239
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 256..276
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 409..423
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 991..1005
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1042..1060
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1072 AA; 120068 MW; 22D17B99B25CA6F1 CRC64;
MKFGRYLAEN QTPEWKRAYI DYRACKKAIK VVARRLGQVK ESGGEGGAGD GDGDGDDSSG
ADDDHGPSAP PRDRSTPDTI KGSLTRRLTR TISQGATPRL TRFSSRPSET RSPRYGSTGT
SPRPPTSAPR VPPPLDLGAP GVDDQDHESH SRPSPNPEEV LNADKSQTQD EDRVGGRDKA
RSRKGVAFSP KADAVVQATI EESSGESGRS SDVGMAQSDS NEPLTGGLDR DKESPKKIGQ
SPKRTPGALW SPRLGGASRN NDSPRTAESS RVTRSPRLGA RSLRSMTLPS PALPMKSPGP
PVRTADNFDE LYKQLEDDEK AFFDLLESEL DKVEKFYVAR ETEATRRAHA LRDQLRELAE
HRKIYHELYP QGIPEWEAKV GRILPIPAVT QGSAPGLAKL RARLGFSSND EGENGTSTSK
PDGSYADGGA IGRTQSPVMN ENERRSLREA MAADKDHQTY SPERYQKYKK DLRNALLEFY
RQLELIKNYR IMNLTGFRKA LKKFEKTTKI VCLEMYTDER ISKATFSKSG VIDGLIKQIE
DLYTAHFEHG DSKKARERLR KQTHEKTHYS SVFRSGIMLG IAAPAAIAAL VECDKPQTRA
ELPAWGGLLQ VYAGLYLPVV FAILFELNLG AYVSARINYE FVMELSRPTI DYRSFLEIPA
FLFLTLSYCF YFTFARVGAE NIAPTTWPAA WLVFVAVFFL NPLPVLRRGT RYWLLRVFFR
VCTPGYSRVE FIAFFLADEL NSLIYSIQNI YFLSCGYAHK WPSDVFGVCK SGKTWPYALL
LCLPAASRFV QCVKRYHDSQ LKIHLINAGK YLSVILQQCL FVYWRSRGSI LNDKAFIVWI
IVAMVSSSYT CTWDFVIDWS LFRPQAGLLR KDLGYSHRYV YYLAMFTNLL IRFVFVWYIP
YSTKHVRLRS FFFALAEMLR RWQWNFFRVE TEHLGNADAY RVTREIPLPY RRLDHDSDDD
DEDGPSSSSG GLAEKSKGGS RGGGSRKSFS VQLDRIRHRL RERRSTSGNG GGGGSGTILG
HEDGESGLSG GRGPDAIDAG PRGHAPQREY EARRPGDSMR SESEIGPGSN LV
//
