ID A0A1B9I073_9TREE Unreviewed; 628 AA.
AC A0A1B9I073;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Xanthine/uracil permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=I206_05659 {ECO:0000313|EMBL:OCF48878.1};
OS Kwoniella pini CBS 10737.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296096 {ECO:0000313|EMBL:OCF48878.1, ECO:0000313|Proteomes:UP000094020};
RN [1] {ECO:0000313|EMBL:OCF48878.1, ECO:0000313|Proteomes:UP000094020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10737 {ECO:0000313|EMBL:OCF48878.1,
RC ECO:0000313|Proteomes:UP000094020};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus pinus CBS10737.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000094020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10737 {ECO:0000313|Proteomes:UP000094020};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
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DR EMBL; KI894013; OCF48878.1; -; Genomic_DNA.
DR RefSeq; XP_019010097.1; XM_019157379.1.
DR AlphaFoldDB; A0A1B9I073; -.
DR STRING; 1296096.A0A1B9I073; -.
DR GeneID; 30174028; -.
DR OrthoDB; 35157at2759; -.
DR Proteomes; UP000094020; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000094020};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 98..117
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 151..170
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..207
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 413..440
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 460..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 565..628
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..610
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 628 AA; 68003 MW; D1A44BCF2A788631 CRC64;
MVSFSPHRIN EAVAKTFIGR WFRLEGSGHP LARPGSKFLT ELRAGTVTAA AMLYIISVNS
SILSDSGGPC VCEGTADDPI CADNNDYALC KNELRRDYVT ATSAISLIST FLMGLLANMP
LGLAPGLGVN AYFAYSQVGF NGTGPISYSE ALAAVFLEGL IFFALTILGL RQWVVRLIPR
SITTAIGCGI GLFLTIIGLS SSGLNVISGG ISTPLQLGGC ASEYADATTG FCNSHVLQDP
RMWLGIFVGG VLTAFLLLYR VKGALLWPIL LVAIISWPRP TSVTAFPHTE LGDSNFDFFK
NVVAARGFKL LGPSNVDWKA YANGKVWVAL ISFLYVDLLD TTGTMVAMSK QAGLYDARDG
DFEGSSVAFL VDSACIAASG LFFGTSPCTP FVESASGISE GGKTGLTAVT TAFWFFISIF
FAPILSNIPA WATGSVLIVV GAMMMENATK VNWDYMGDAI PAFVVIAVIP FTYNVAYGII
AGLILFILLH NVPKVLGMIS PRLLPPGWRD LKEPYNSTAF LKQPNGKGRV SFLALLPPWL
RKLVSGEKRF WEYTHEEMER ILEGRKISQE SDDAAAKMRQ EERDEMRKRM GEEVVSTEER
KSEDHSDDVN ALEQGIMASG SAYETERK
//
