ID A0A1B9I2R1_9TREE Unreviewed; 1612 AA.
AC A0A1B9I2R1;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 03-MAY-2023, entry version 28.
DE RecName: Full=Kinesin motor domain-containing protein {ECO:0000259|PROSITE:PS50067};
GN ORFNames=I206_04331 {ECO:0000313|EMBL:OCF49804.1};
OS Kwoniella pini CBS 10737.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296096 {ECO:0000313|EMBL:OCF49804.1, ECO:0000313|Proteomes:UP000094020};
RN [1] {ECO:0000313|EMBL:OCF49804.1, ECO:0000313|Proteomes:UP000094020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10737 {ECO:0000313|EMBL:OCF49804.1,
RC ECO:0000313|Proteomes:UP000094020};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus pinus CBS10737.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000094020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10737 {ECO:0000313|Proteomes:UP000094020};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Kinesin family. {ECO:0000256|PROSITE-ProRule:PRU00283}.
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DR EMBL; KI894011; OCF49804.1; -; Genomic_DNA.
DR RefSeq; XP_019011023.1; XM_019156065.1.
DR STRING; 1296096.A0A1B9I2R1; -.
DR GeneID; 30172700; -.
DR OrthoDB; 1466272at2759; -.
DR Proteomes; UP000094020; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0003777; F:microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR InterPro; IPR027640; Kinesin-like_fam.
DR InterPro; IPR001752; Kinesin_motor_dom.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR47968; CENTROMERE PROTEIN E; 1.
DR PANTHER; PTHR47968:SF36; CENTROMERE-ASSOCIATED PROTEIN E; 1.
DR Pfam; PF00225; Kinesin; 1.
DR PRINTS; PR00380; KINESINHEAVY.
DR SMART; SM00129; KISc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50067; KINESIN_MOTOR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Nucleotide-binding {ECO:0000256|PROSITE-ProRule:PRU00283};
KW Reference proteome {ECO:0000313|Proteomes:UP000094020}.
FT DOMAIN 173..511
FT /note="Kinesin motor"
FT /evidence="ECO:0000259|PROSITE:PS50067"
FT REGION 1..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 727..749
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 946..969
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1048..1074
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1481..1521
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1533..1554
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1580..1612
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 528..580
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1324..1379
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 262..269
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00283"
SQ SEQUENCE 1612 AA; 178917 MW; 885FD5F17B9E2CBD CRC64;
MSLSPSKHRT LSRQPSSPSL AVGLPPALPE SNIMQPSSPS KLAKSRSRKR IHRGDVSSSA
ASSDNEEEGL TQITPKRKII NPIEAPLPLS TGKKPKKKMT LQERLAAAAS AKAGTSEGGI
KAKVNSIADF SSFISEATQI SESSSTSKVS MTPQTRSELL SSRSIASSSS SDKVVVCVRI
KPTSHPFANI AYEISPTSLT LSDDHPKVKQ RGGKAGREDG YTYTFDKLLQ FPSTTPDLYG
AKVAPLVDKA MNGFNSTIFA YGQTGSGKSF TMTGTADELG IIPCAIDGVF DAITADTERA
FLLRVSYIEI YNETLRDLLN FKKGPLKDDE KPAIHYAKGK VYVDPLVEEI VSTPQDVIDL
LEKGNAQRRV GATDWAIKLT YRIQNERSSR SHCVFTIVVE SRPRDGDGDD DIRLSRLDLA
GSEKAVSDSE RRGEGKHINQ SLLALREVIN KLTEKTKASH VPYRNSKLTH LLENALGGDS
NICVICTMSA EEEHCGETLE TLKFAGRCSQ VKTNAKKNVL QSSERALIKA KDQEIEDLRL
RLATFTKKDV NPISDLAESV AAMEARKSKL VAQLSKLNGE ILTSELPRSG SGLPLSPPKP
KRRRISDFSA MISTGSGRTG IGLGTPKKTV DRRAISGMSR LTEESEEMAG IMGTLEQAAG
GGVAKSFEQD RALAAARRNL ATKEEELSLA NRNLASALAR ASQLSERDAK ISTLETELRQ
ALDALSSTQQ KLQRTESDMG DQNAQLESTR SEMVAKIEER SKRIDELENK VIDLRNSREE
LVLEDQGRLE EVQKRSEELS KEKEGLECTL KRLQHEALEQ GGEVERLKGE IATLVDRGAE
TKAQTEISSL QIAQLEDSMT QLKKQLEENQ YSQASREATL QTEKAIAERQ VEEARADLDR
FQREAMSNEA NVLGQLRDEI GNLRKARDED KLAFEKMRLE LEREIEEGKE RSKDELTQAK
NEAEERERKL REQVAEALKT LQEAAKANDT LQQTIRLETE SKATIQQEKA DIVMKLVRAT
QDMEDIATSN KDLEERLQSA LNIKTTLENE RDEARNRLSA SDGAADQLKS ETNARQDAEV
RLELAINKLH EMEDRLGAMQ KDLEVQEKRL EAEAASRQDA ENRIQDIALA RDQAVAAERE
KEKAADEEKK CRIAAEKRIE ELSMQREANL EGVKEMRRKM DLESSSRKEV EAELEKLKAR
QSAENSGQDK LRAKLLETIN AKEELSRQLS ELVQSVKKKD EELRSVLATR NDMSNTIANL
EEVHKALVEQ NEKAESCLKT AENKIATHSA LERSVLDLRH QLEAERTGRI AAESQVTKVS
QELITKHESA QQVLENELIS LRQALKVAQK EKSDAQSEAE LERVKADELC SELNELKSRS
EVTITTSVSS RLRHSAPGPG WGTDKDMSAT ALDSLRSRRG VSAGTHVLDA SLSMLKARDD
DEIERLERII EVQKEIIDEQ REKIERWAKE MEKQREIVRL LTNDNSQPSP IPARTRSPRG
HGKSHSISHS PAPTPLPNAK GLVSSFTARN LALPTSPSPL PMHPSQFTNS SARKARRVTI
EHDMDKLTES SKVIKAKAIF ESPEKNAAPA TPPKIPLRAT QSIRSVPRQR RP
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