ID A0A1B9I5D4_9TREE Unreviewed; 708 AA.
AC A0A1B9I5D4;
DT 02-NOV-2016, integrated into UniProtKB/TrEMBL.
DT 02-NOV-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Translocation protein SEC63 {ECO:0000313|EMBL:OCF50701.1};
GN ORFNames=I206_02757 {ECO:0000313|EMBL:OCF50701.1};
OS Kwoniella pini CBS 10737.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Tremellomycetes;
OC Tremellales; Cryptococcaceae; Kwoniella.
OX NCBI_TaxID=1296096 {ECO:0000313|EMBL:OCF50701.1, ECO:0000313|Proteomes:UP000094020};
RN [1] {ECO:0000313|EMBL:OCF50701.1, ECO:0000313|Proteomes:UP000094020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10737 {ECO:0000313|EMBL:OCF50701.1,
RC ECO:0000313|Proteomes:UP000094020};
RG The Broad Institute Genome Sequencing Platform;
RA Cuomo C., Litvintseva A., Chen Y., Heitman J., Sun S., Springer D.,
RA Dromer F., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A.,
RA Alvarado L., Berlin A.M., Chapman S.B., Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., McCowan C.,
RA Murphy C., Pearson M., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Cryptococcus pinus CBS10737.";
RL Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000094020}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 10737 {ECO:0000313|Proteomes:UP000094020};
RA Cuomo C., Litvintseva A., Heitman J., Chen Y., Sun S., Springer D.,
RA Dromer F., Young S., Zeng Q., Chapman S., Gujja S., Saif S., Birren B.;
RT "Evolution of pathogenesis and genome organization in the Tremellales.";
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KI894009; OCF50701.1; -; Genomic_DNA.
DR RefSeq; XP_019011920.1; XM_019154517.1.
DR AlphaFoldDB; A0A1B9I5D4; -.
DR STRING; 1296096.A0A1B9I5D4; -.
DR GeneID; 30171126; -.
DR OrthoDB; 1605at2759; -.
DR Proteomes; UP000094020; Unassembled WGS sequence.
DR GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR CDD; cd06257; DnaJ; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.10.287.110; DnaJ domain; 1.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR001623; DnaJ_domain.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR036869; J_dom_sf.
DR InterPro; IPR004179; Sec63-dom.
DR PANTHER; PTHR24075; SEC63 DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR24075:SF0; TRANSLOCATION PROTEIN SEC63 HOMOLOG; 1.
DR Pfam; PF00226; DnaJ; 1.
DR Pfam; PF02889; Sec63; 1.
DR PRINTS; PR00625; JDOMAIN.
DR SMART; SM00271; DnaJ; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF46565; Chaperone J-domain; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
DR PROSITE; PS50076; DNAJ_2; 1.
PE 4: Predicted;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000094020};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 13..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..92
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 250..269
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 104..174
FT /note="J"
FT /evidence="ECO:0000259|PROSITE:PS50076"
FT REGION 626..708
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 278..305
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 629..647
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 686..708
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 708 AA; 79710 MW; 026995DCDF2A4309 CRC64;
MAPGISYDES GSLASYFGVT FLAIILIPWT LSSTKSEKKK LLKPLCPCPQ CTSSPRRVHS
IKSTKRKRKF LKKTIPLVIG WTIFAYLCYS LSQAPRLEGE TIYNPFEILG LSDSTNEKQI
KKHYKKLSLQ YHPDKIKLAE NQTKEDAEQK FVELTKAYKS LTDEVTRENL AKYGNPDGPQ
QREDKIAIPQ WVVEGKNSIW VLGAYGLVLG GGIPWAVGRW WFAQRKLTRD GILNPTAELF
FHQLRDDTDF FSLISLLASA LEFGAVLGFK KRGSKKARKE RQSKIDELEK VIEARKAEIG
LEENALMRRE NRINVTTAVA KRARALLWAH LLRIDLNDHQ LESEKLAVLR VTPPLLSALL
NISLAHNWLT TSLLVIKLQP ALVQALPTDL SPLAQLPDVT PEQGQELQII NKAEGLRWLE
KWIKTEKKSV SEQAVNVAKY WPRLEIIDAE FKVGDETLVT PSSIVELTYK ARYVYPTTPL
SLLSKPKSLL PNGQLKEEVA DSVADVEDSV TQVAEEKEKP AEIGEKKALE VPPNGFAHAP
YWPQQLRKPH FYVLLGDSKL DKVIVPPVKI TDIPLPKPDG SPTEPKEFTL QFQAPPQANL
YSFVAHWRSD TFLGSDVQVP IMLKVEDIPQ EEEIEDDDDD DISEPEEDTL AGQMAMMRGG
KVKPSAVHGT PDDDDDSEEE YESSSDEETP AKNKRVRAYN EDSDTDSD
//
